Protein Alignment Gba1b and Gba1

DIOPT Version :10

• Sequence 1: NP_001097888.1
• Gene: Gba1b / 318721
• FlyBaseID: FBgn0051414
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_032120.1
• Gene: Gba1 / 14466
• MGIID: 95665
• Length: 515
• Species: Mus musculus
• Alignment Length: 572
• Identity: 188/572 - (32%)
• Similarity: 288/572 - (50%)
• Gaps: 68/572 - (11%)

  Fly     4 MKTPLLG-FLTTVIAISAGAPDWQLPCDLRETSHGS-VCVCNSTYCDYLEPPQLTDISQIVVISS 66
            |...|:| ||...::.:.||.    ||..:...:.| |||||::|||.|:|..|..:.......|
Mouse     1 MAARLIGFFLFQAVSWAYGAQ----PCIPKSFGYSSVVCVCNASYCDSLDPVTLPALGTFSRYES 61

  Fly    67 SKDGLRFKKTTGDLSKKKPITIDDKQFTDENFKADAIVVDQERAWLQLANIPQSLFINASIKTYR 131
            ::.|.|.:.:.|                       ||..::....|.|...|
Mouse    62 TRRGRRMELSVG-----------------------AIQANRTGTGLLLTLQP------------- 90

  Fly   132 IFVKREQSFQNVSIFGGAFTGTVSYLLKELPVELQDHVYRSYFHPVGIAYNTIRMSIGGSDFDME 196
                 |:.||.|..||||.|...:..:..|....|..:.||||...||.||.||:.:...||.:.
Mouse    91 -----EKKFQKVKGFGGAMTDATALNILALSPPTQKLLLRSYFSTNGIEYNIIRVPMASCDFSIR 150

  Fly   197 PWAYNELPLHDPKLSNFTELDPRDLQKVEQL-KRLKIIGKVDSLKIMGAAWSAPTWMKSNNRWTG 260
            .:.|.:.| :|.:||||:..:.....|:..: :.||:..:  .:.:..:.|::|||:|:|.|..|
Mouse   151 VYTYADTP-NDFQLSNFSLPEEDTKLKIPLIHQALKMSSR--PISLFASPWTSPTWLKTNGRVNG 212

  Fly   261 FGQLKSE----YYQTWALYHLKFLELMRSKNMPIWAISTGNEPLNGVIGFFFVHFMSMGWTPWQQ 321
            .|.||.:    ::||||.|.:|||:......:..||::..|||..|:  |....|..:|:||..|
Mouse   213 KGSLKGQPGDIFHQTWANYFVKFLDAYAKYGLRFWAVTAENEPTAGL--FTGYPFQCLGFTPEHQ 275

  Fly   322 AIWLNDNLGPTIRNSA-ESKVLIFGNDDQRYTYPTWFRKMRSSRNNSLNYLDGLAVHWYWDELI- 384
            ..:::.:|||.:.||: :.|:|:.  ||||...|.|...:.|. ..:..|:.|:|||||.|.|.
Mouse   276 RDFISRDLGPALANSSHDVKLLML--DDQRLLLPRWAEVVLSD-PEAAKYVHGIAVHWYMDFLAP 337

  Fly   385 GPQLIDQAHTDMPNKLLLNTESCIGDKPWQTHGPELGSWQRGESYMRAYTQDLTHNFNGWLDWNL 449
            ....:.:.|...||.:|..:|:|:|.|.|: ....||||.||..|..:...:|.::..||.||||
Mouse   338 AKATLGETHRLFPNTMLFASEACVGSKFWE-QSVRLGSWDRGMQYSHSIITNLLYHVTGWTDWNL 401

  Fly   450 VLDEQGGPNYVKNFVDAPIIVNATSRSEIYKQPIFYAIGHFSKFLPPDSVRIETRIENQSNPFTQ 514
            .|:.:||||:|:||||:||||: ..:...||||:||.:||||||:|..|.|: ..:.::|   |.
Mouse   402 ALNPEGGPNWVRNFVDSPIIVD-IPKDAFYKQPMFYHLGHFSKFIPEGSQRV-ALVASES---TD 461

  Fly   515 LSVVGFQRPDGSVALIIYNGQNLPVDVTLDDSQRGAIQLRLPPRSWHTVLYK 566
            |..|...|||||..:::.|..:..|.:|:.|...|.::...|..|.||.|::
Mouse   462 LETVALLRPDGSAVVVVLNRSSEDVPLTISDPDLGFLETVSPGYSIHTYLWR 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gba1b	NP_001097888.1	XynC	112..566	CDD:444271	161/460 (35%)
Gba1	NP_032120.1	Glyco_hydro_30	97..445	CDD:451560	132/357 (37%)
		Glyco_hydro_30C	448..510	CDD:465376	19/65 (29%)