Protein Alignment Qsox4 and QSOX2

DIOPT Version :10

• Sequence 1: NP_732891.1
• Gene: Qsox4 / 318720
• FlyBaseID: FBgn0051413
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: NP_859052.3
• Gene: QSOX2 / 169714
• HGNCID: 30249
• Length: 698
• Species: Homo sapiens
• Alignment Length: 601
• Identity: 164/601 - (27%)
• Similarity: 253/601 - (42%)
• Gaps: 135/601 - (22%)

  Fly    14 LCVLILSA-------GRGELLFNADDNVVQLDFASFESGLSEPTSGKLVQFFNGFCEESQNFIPA 71
            |.||:.:|       |...|....:|.|..||..|.....:..::..||||::.:|.....:.|.
Human    36 LLVLLAAAAVGPGAGGAARLYRAGEDAVWVLDSGSVRGATANSSAAWLVQFYSSWCGHCIGYAPT 100

  Fly    72 FKNLSRKLYKWHRLLKVHVLDCGKDENDMICSIYSIRKTPTLRYFPPSYK--------LAPDNLG 128
            ::.|:..:..|...::|..|||.:::|..:|..|.|...||.|||....|        ..||
Human   101 WRALAGDVRDWASAIRVAALDCMEEKNQAVCHDYDIHFYPTFRYFKAFTKEFTTGENFKGPD--- 162

  Fly   129 TEITHRNPKEIQSKLALNLQ------------KLDYFK---MFKRQDNVAHIFQTHKDIEYVAFV 178
                 |..:.::..:...||            :||..:   :....||        :...|||.|
Human   163 -----RELRTVRQTMIDFLQNHTEGSRPPACPRLDPIQPSDVLSLLDN--------RGSHYVAIV 214

  Fly   179 FQMCLDHFLPHLETGNSMEEKYASQGDCNEDNPIVSLIGRNTLLELLPYRKVVV-RIFDNHDVY- 241
            |:            .||                  |.:||..:|:|:||..:|| |..|....:
Human   215 FE------------SNS------------------SYLGREVILDLIPYESIVVTRALDGDKAFL 249

  Fly   242 NKFGISPVPN--LVVLVNKAGKLLFLTPEMDSSKAYVAAIKQFLIFVDLKPQKPLPKTP-PANIS 303
            .|.|:|.||:  |:......|.:..:.|......:|:.::...     .|...|||:.| ....|
Human   250 EKLGVSSVPSCYLIYPNGSHGLINVVKPLRAFFSSYLKSLPDV-----RKKSLPLPEKPHKEENS 309

  Fly   304 EALRYEIFEQHKHHPSRIYRADLERAIDQILNVKFPGTTHFAGAKIVVLRNFVKLIYNSSPLKPE 368
            |.:.:..|::     |::|..|||..:..:|.|:.......|||::..|::||.::....|.:|.
Human   310 EIVVWREFDK-----SKLYTVDLESGLHYLLRVELAAHKSLAGAELKTLKDFVTVLAKLFPGRPP 369

  Fly   369 AR-------EKLANL------YYS----LHVKKQLSGVGFKNLLLKSVKDYVFDGKQYVGCIASR 416
            .:       |.||:|      |.:    ::.|.::||:...|.:            ::|||..||
Human   370 VKKLLEMLQEWLASLPLDRIPYNAVLDLVNNKMRISGIFLTNHI------------KWVGCQGSR 422

  Fly   417 PSLRGFNCSLWVLFHYLSVESK-----------KLKPKSVLLVFLGYVRFFMNCKECDMKISEFK 470
            ..|||:.||||.|||.|:||:.           :..|::||.....||..|..||||.....|..
Human   423 SELRGYPCSLWKLFHTLTVEASTHPDALVGTGFEDDPQAVLQTMRRYVHTFFGCKECGEHFEEMA 487

  Fly   471 KLRPIANVTNDDEQILWLWEAHNYVNKQLAGDSTEDPKFPKIQFPSERDCPKCR---NNATEWRT 532
            | ..:.:|...|:.|||||:.||.||.:|||..:|||:|||:|:|:...||.|.   .....|..
Human   488 K-ESMDSVKTPDQAILWLWKKHNMVNGRLAGHLSEDPRFPKLQWPTPDLCPACHEEIKGLASWDE 551

  Fly   533 EEVLHYLKGIYTLKNL 548
            ..||.:||..|...||
Human   552 GHVLTFLKQHYGRDNL 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Qsox4	NP_732891.1	PDI_a_QSOX	32..145	CDD:239290	30/120 (25%)
		FAD_SOX	319..>376	CDD:465728	18/63 (29%)
		Evr1_Alr	424..515	CDD:461423	43/101 (43%)
QSOX2	NP_859052.3	PDI_a_QSOX	61..174	CDD:239290	30/120 (25%)
		QSOX_Trx1	185..292	CDD:465653	31/144 (22%)
		FAD_SOX	318..421	CDD:465728	27/119 (23%)
		Evr1_Alr	430..531	CDD:461423	43/101 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	570..624