DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Qsox4 and qsox2

DIOPT Version :9

Sequence 1:	NP_732891.1	Gene:	Qsox4 / 318720	FlyBaseID:	FBgn0051413	Length:	561	Species:	Drosophila melanogaster
Sequence 2:	NP_001121505.1	Gene:	qsox2 / 100158617	XenbaseID:	XB-GENE-986398	Length:	657	Species:	Xenopus tropicalis

Alignment Length:	591	Identity:	147/591 - (24%)
Similarity:	249/591 - (42%)	Gaps:	107/591 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 FSLLLCVLILSAGRG-ELLFNADDNVVQLDFASFESGLSEPTSGKLVQFFNGFCEESQNFIPAFK 73
            |..:|.||:|....| |.|:...|.:..|:..|....:...:|..|::|::.:|....|:.|.::
Frog     8 FRSVLAVLVLFGSVGAEALYGPADPLSILNKESVTRAVFNSSSAWLLEFYSSWCGHCINYAPTWR 72

  Fly    74 NLSRKLYKWHRLLKVHVLDCGKDENDMICSIYSIRKTPTLRYFPPSYKLAPDNLGTEITH----- 133
            .|:|.:..|...:|:.||||.:::|...|..:.:...||.|:|..        ..||.|.
Frog    73 ALARDVSDWDPAIKIGVLDCAEEDNYGTCKDFGVTLYPTFRFFKA--------FTTEFTQGENYK 129

  Fly   134 -RNPKEIQSKLALNLQKLDYFKMFKRQ--------------DNVAHIFQTHKDIEYVAFVFQMCL 183
             .|.:|||:   :....:|:.:....|              ..::.:. |.|...|.|.:|:
Frog   130 AGNDREIQT---VRQVIIDFLQTSPAQSKPQACPTLEPISSSEISSLL-TQKQSHYTAIIFE--- 187

  Fly   184 DHFLPHLETGNSMEEKYASQGDCNEDNPIVSLIGRNTLLELLPYRKVVVR--IFDNHDVYNKFGI 246
                        .||.|               :||..:|:|:.|..:|||  :..:..:..|.||
Frog   188 ------------SEESY---------------VGREVMLDLIRYSNMVVRRALPSDKAILEKLGI 225

  Fly   247 SPVPNLVVLVNKAGKLLFLTPEMDSSKAYVAAIK----QFLIFVDLKP--QKPLPK-TPPANISE 304
            ..||:..::            :.:.|...:..:|    |....:...|  :|.||. |..:.:::
Frog   226 GSVPSCYLI------------QPNGSHGLIKEVKCLRAQLSSHLKALPNVRKRLPSDTAHSGLNK 278

  Fly   305 ALRYEIFEQHKHHPSRIYRADLERAIDQILNVKFPGTTHFAGAKIVVLRNFVKLIYNSSPLKPEA 369
            ..:.......:...|::|.||||..:..:|..:........|.|:...::||.::|...|.:|..
Frog   279 DAQQGDVAMKEFDRSKLYMADLESGLHYVLRAELANHRTLEGEKLKTFKDFVTILYKLFPGRPHV 343

  Fly   370 REKLANLYYSLHVKKQLSGVGFKNLL------LKSVKDYVFDGKQYVGCIASRPSLRGFNCSLWV 428
            .:.|..|...| |...|..:.:..:|      ::....::.:..|:|||..|:..|||:.||||.
Frog   344 MKLLETLQEWL-VSMPLDKIPYDAILDLVNNRMRISGIFLTNHTQWVGCRGSKSHLRGYPCSLWK 407

  Fly   429 LFHYLSVESK-----------KLKPKSVLLVFLGYVRFFMNCKECDMKISEFKKLRPIANVTNDD 482
            |||.|:|::.           ...|::||.....|:|.|..|:||........| ..:.:|...|
Frog   408 LFHSLTVQASVKPDALANTALGADPQAVLQTMRSYIREFFGCRECAKHFEAMAK-ETMDSVRTPD 471

  Fly   483 EQILWLWEAHNYVNKQLAGDSTEDPKFPKIQFPSERDCPKCR----NNATEWRTEEVLHYLKGIY 543
            :.:||||..||.||.:|:|..:|||||||:|:|:...|..|.    .....|...|||.:||..|
Frog   472 QAVLWLWRKHNAVNNRLSGAPSEDPKFPKVQWPTSDLCSACHGQTGGGTQSWNENEVLSFLKRYY 536

  Fly   544 TLKNLS 549
            ..:.:|
Frog   537 GKQEIS 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Qsox4	NP_732891.1	PDI_a_QSOX	32..145	CDD:239290	30/118 (25%)
Qsox4	NP_732891.1	Evr1_Alr	425..512	CDD:282612	36/97 (37%)
qsox2	NP_001121505.1	PDI_a_QSOX	31..145	CDD:239290	30/124 (24%)
		QSOX_Trx1	156..263	CDD:375557	25/149 (17%)
		FAD_SOX	291..394	CDD:375797	24/103 (23%)
		Evr1_Alr	403..503	CDD:368111	38/100 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H65608
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D158783at33208
OrthoFinder	1	1.000	-	-		FOG0001506
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22897
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.110