Protein Alignment Dsor1 and OXSR1

DIOPT Version :10

• Sequence 1: NP_511098.1
• Gene: Dsor1 / 31872
• FlyBaseID: FBgn0010269
• Length: 396
• Species: Drosophila melanogaster
• Sequence 2: XP_011532633.1
• Gene: OXSR1 / 9943
• HGNCID: 8508
• Length: 580
• Species: Homo sapiens
• Alignment Length: 329
• Identity: 95/329 - (28%)
• Similarity: 152/329 - (46%)
• Gaps: 69/329 - (20%)

  Fly    94 GSGNGGVVMKVRHTHTHLIMARKLIHLEVKPAIKKQILRELKVLHECNFPHIVGFYGAFYSDGEI 158
            |||...||...........:|.|.|:||.......::|:|::.:.:|:.|:||.:|.:|....|:
Human    77 GSGATAVVQAAYCAPKKEKVAIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDEL 141

  Fly   159 SICMEYMDGGSLDLILK--------RAGRIPESILGRITLAVLKGLSYLRDNHAIIHRDVKPSNI 215
            .:.|:.:.|||:..|:|        ::|.:.||.:..|...||:||.||..| ..||||||..||
Human   142 WLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLEGLEYLHKN-GQIHRDVKAGNI 205

  Fly   216 LVNSSGEIKICDFGVSGQLI-------DSMANSFVGTRSYMSPERLQGTH-YSVQSDIWSLGLSL 272
            |:...|.::|.|||||..|.       :.:..:||||..:|:||.::... |..::||||.|::.
Human   206 LLGEDGSVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITA 270

  Fly   273 VEMAIGMYP---IPPPNTATLESIFADNAEESGQPTDEPRAMAIFELLDYIVNEPPPKLEH---- 330
            :|:|.|..|   .||                             .::|...:...||.||.
Human   271 IELATGAAPYHKYPP-----------------------------MKVLMLTLQNDPPSLETGVQD 306

  Fly   331 ----KIFSTEFKDFVDICLKKQPDERADLKTLLSHPWIRKAE----LEEVDISGWVCKTMDLPPS 387
                |.:...|:..:.:||:|.|::|.....||.|.:.:||:    |:|        ||:...|:
Human   307 KEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLRHKFFQKAKNKEFLQE--------KTLQRAPT 363

  Fly   388 TPKR 391
            ..:|
Human   364 ISER 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dsor1	NP_511098.1	PKc_MEK	85..382	CDD:132946	92/318 (29%)
OXSR1	XP_011532633.1	STKc_OSR1_SPAK	77..344	CDD:270787	87/296 (29%)
		OSR1_C	487..544	CDD:463491