DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dsor1 and MKK6

DIOPT Version :9

Sequence 1:	NP_511098.1	Gene:	Dsor1 / 31872	FlyBaseID:	FBgn0010269	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_200469.1	Gene:	MKK6 / 835759	AraportID:	AT5G56580	Length:	356	Species:	Arabidopsis thaliana

Alignment Length:	388	Identity:	150/388 - (38%)
Similarity:	211/388 - (54%)	Gaps:	53/388 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KLNLVLPPVNTEATVAAATVAPTPPFKTPSGT--DTHSLLGKPKTSIDALTETLEGLDMGDTERK 67
            :|.|.:|          |..:|...|.|.|||  |...||.:            :||.:...|::
plant    10 QLKLSVP----------AQESPISSFLTASGTFHDGDFLLNQ------------KGLRLTSDEKQ 52

  Fly    68 RIKMFLSQKEKIGELSDEDLEKLGELGSGNGGVVMKVRHTHTHLIMARKLIHLEVKPAIKKQILR 132
            ..:.  ..||...|::.||||.:..:|.|:||||..|||.......|.|:|.:.::..|:|||::
plant    53 SRQS--DSKELDFEITAEDLETVKVIGKGSGGVVQLVRHKWVGKFFAMKVIQMNIQEEIRKQIVQ 115

  Fly   133 ELKV---LHECNFPHIVGFYGAFYSDGEISICMEYMDGGSLDLILKRAGRIPESILGRITLAVLK 194
            |||:   ..:|  ||:|..|.:||.:|..|:.:||||.|||..::::...|.|..|..:...||.
plant   116 ELKINQASSQC--PHVVVCYHSFYHNGAFSLVLEYMDRGSLADVIRQVKTILEPYLAVVCKQVLL 178

  Fly   195 GLSYLRDNHAIIHRDVKPSNILVNSSGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERLQGT 257
            ||.||.:...:||||:||||:|||..||:||.|||||..|..||.  ::||||.:||||||:.|:
plant   179 GLVYLHNERHVIHRDIKPSNLLVNHKGEVKISDFGVSASLASSMGQRDTFVGTYNYMSPERISGS 243

  Fly   258 HYSVQSDIWSLGLSLVEMAIGMYPIPPPNTATLESIFADNAEESGQPTDEPRAMAIFELLDYIVN 322
            .|...|||||||:|::|.|||.:|.       |||            .|:....:.:|||..||.
plant   244 TYDYSSDIWSLGMSVLECAIGRFPY-------LES------------EDQQNPPSFYELLAAIVE 289

  Fly   323 EPPPKLEHKIFSTEFKDFVDICLKKQPDERADLKTLLSHPWIRKAELEEVDISGWVCKTMDLP 385
            .|||......||.||..||..|::|.|..||....|||||:|:|.|.:::|: |.:..|::.|
plant   290 NPPPTAPSDQFSPEFCSFVSACIQKDPPARASSLDLLSHPFIKKFEDKDIDL-GILVGTLEPP 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dsor1	NP_511098.1	PKc_MEK	85..382	CDD:132946	129/301 (43%)
Dsor1	NP_511098.1	S_TKc	88..364	CDD:214567	121/280 (43%)
MKK6	NP_200469.1	PKc_MAPKK_plant_like	68..335	CDD:132954	126/287 (44%)
MKK6	NP_200469.1	S_TKc	71..331	CDD:214567	121/280 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	225	1.000	Domainoid score	I683
eggNOG	1	0.900	-	-		E1_KOG0581
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	235	1.000	Inparanoid score	I1115
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D688282at2759
OrthoFinder	1	1.000	-	-		FOG0000715
OrthoInspector	1	1.000	-	-		otm2995
orthoMCL	1	0.900	-	-		OOG6_100914
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X438
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.730