Protein Alignment Dsor1 and MAP2K4

DIOPT Version :9

• Sequence 1: NP_511098.1
• Gene: Dsor1 / 31872
• FlyBaseID: FBgn0010269
• Length: 396
• Species: Drosophila melanogaster
• Sequence 2: NP_001268364.1
• Gene: MAP2K4 / 6416
• HGNCID: 6844
• Length: 410
• Species: Homo sapiens
• Alignment Length: 415
• Identity: 152/415 - (36%)
• Similarity: 212/415 - (51%)
• Gaps: 88/415 - (21%)

  Fly     5 KLNLVLPPVNTEATVAAATVAPTPPFKTPSGTD--------THSLLGKPKTSIDALTETLEGLDM 61
            |||...||..   :.|..|:.|     .|:|..        |||:....|..|
Human    56 KLNFANPPFK---STARFTLNP-----NPTGVQNPHIERLRTHSIESSGKLKI------------ 100

  Fly    62 GDTERKRIKMFLSQKEKIGELSDEDLEKLGELGSGNGGVVMKVRHTHTHLIMARKLIHLEVKPAI 126
                         ..|:..:.:.|||:.|||:|.|..|.|.|:.|..:..|||.|.|...|....
Human   101 -------------SPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKE 152

  Fly   127 KKQILRELK-VLHECNFPHIVGFYGAFYSDGEISICMEYMDGGSLDLILKRA-----GRIPESIL 185
            :||:|.:|. |:...:.|:||.||||.:.:|:..||||.| ..|.|...|..     ..|||.||
Human   153 QKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELM-STSFDKFYKYVYSVLDDVIPEEIL 216

  Fly   186 GRITLAVLKGLSYLRDNHAIIHRDVKPSNILVNSSGEIKICDFGVSGQLIDSMANS-FVGTRSYM 249
            |:||||.:|.|::|::|..|||||:||||||::.||.||:||||:||||:||:|.: ..|.|.||
Human   217 GKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYM 281

  Fly   250 SPERL------QGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPNTATLESIFADNAEESGQPTDEP 308
            :|||:      ||  |.|:||:||||::|.|:|.|.:|.|..|
Human   282 APERIDPSASRQG--YDVRSDVWSLGITLYELATGRFPYPKWN---------------------- 322

  Fly   309 RAMAIFELLDYIVNEPPPKL---EHKIFSTEFKDFVDICLKKQPDERADLKTLLSHPWIRKAELE 370
               ::|:.|..:|...||:|   |.:.||..|.:||::||.|...:|...|.||.||:|...|..
Human   323 ---SVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPFILMYEER 384

  Fly   371 EVDISGWVCKTMDLPPSTPKRNTSP 395
            .|:::.:|||.:|..|:||   :||
Human   385 AVEVACYVCKILDQMPATP---SSP 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dsor1	NP_511098.1	PKc_MEK	85..382	CDD:132946	130/312 (42%)
		S_TKc	88..364	CDD:214567	121/291 (42%)
MAP2K4	NP_001268364.1	PKc_MKK4	106..396	CDD:270790	130/317 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D688282at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2221
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.950