Protein Alignment Dsor1 and MAP2K6

DIOPT Version :9

• Sequence 1: NP_511098.1
• Gene: Dsor1 / 31872
• FlyBaseID: FBgn0010269
• Length: 396
• Species: Drosophila melanogaster
• Sequence 2: XP_011523328.1
• Gene: MAP2K6 / 5608
• HGNCID: 6846
• Length: 337
• Species: Homo sapiens
• Alignment Length: 363
• Identity: 128/363 - (35%)
• Similarity: 190/363 - (52%)
• Gaps: 60/363 - (16%)

  Fly    26 PTPPFKTPSGTDTHSLLGKPKTSIDALTETLEGLDMGDTERKRIKMFLSQKEKIGELSDEDLEKL 90
            |...|:.|..:.|      |...:|:                  |..:|...:..|:..:|||.:
Human    19 PKEAFEQPQTSST------PPRDLDS------------------KACISIGNQNFEVKADDLEPI 59

  Fly    91 GELGSGNGGVVMKVRHTHTHLIMARKLIHLEVKPAIKKQILRELKV-LHECNFPHIVGFYGAFYS 154
            .|||.|..|||.|:||..:..|||.|.|...|....:|::|.:|.: :...:.|..|.||||.:.
Human    60 MELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFR 124

  Fly   155 DGEISICMEYMDGGSLD----LILKRAGRIPESILGRITLAVLKGLSYLRDNHAIIHRDVKPSNI 215
            :|::.||||.|| .|||    .::.:...|||.|||:|.::::|.|.:|....::|||||||||:
Human   125 EGDVWICMELMD-TSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNV 188

  Fly   216 LVNSSGEIKICDFGVSGQLIDSMANSF-VGTRSYMSPER----LQGTHYSVQSDIWSLGLSLVEM 275
            |:|:.|::|:||||:||.|:||:|.:. .|.:.||:|||    |....|||:|||||||::::|:
Human   189 LINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIEL 253

  Fly   276 AIGMYPIPPPNTATLESIFADNAEESGQPTDEPRAMAIFELLDYIVNEPPPKLEHKIFSTEFKDF 340
            ||..:|.                :..|.|         |:.|..:|.||.|:|....||.||.||
Human   254 AILRFPY----------------DSWGTP---------FQQLKQVVEEPSPQLPADKFSAEFVDF 293

  Fly   341 VDICLKKQPDERADLKTLLSHPWIRKAELEEVDISGWV 378
            ...||||...||.....|:.||:....|.:..|::.:|
Human   294 TSQCLKKNSKERPTYPELMQHPFFTLHESKGTDVASFV 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dsor1	NP_511098.1	PKc_MEK	85..382	CDD:132946	119/304 (39%)
		S_TKc	88..364	CDD:214567	114/285 (40%)
MAP2K6	XP_011523328.1	PKc_MKK3_6	54..336	CDD:173729	119/304 (39%)
		S_TKc	57..317	CDD:214567	114/285 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D688282at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2221
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.950