DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dsor1 and map2k5

DIOPT Version :9

Sequence 1:	NP_511098.1	Gene:	Dsor1 / 31872	FlyBaseID:	FBgn0010269	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	XP_017947570.1	Gene:	map2k5 / 549042	XenbaseID:	XB-GENE-960353	Length:	474	Species:	Xenopus tropicalis

Alignment Length:	387	Identity:	139/387 - (35%)
Similarity:	213/387 - (55%)	Gaps:	65/387 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 KTPSGTDTHSL-----LGKPKTSIDALTETLEG--LDMGDTERKRIKMFLSQKEKIGELSDEDLE 88
            |.|...:.|.|     .|....|..::.:.:.|  |.....|.|:|   |:.    |::::.|::
Frog   110 KPPGKRNIHGLKVNTRAGSSSNSSPSVPDNIAGNSLKKSSAELKKI---LAN----GQINELDIQ 167

  Fly    89 KLGELGSGNGGVVM--------------------------KVRHTHTHLIMARKLIHLEVKPAIK 127
            ....||.||||.|.                          |..|..:..|:|.|:|.|::...::
Frog   168 CRDILGHGNGGTVYNWPIFAMSIGRTSEDLDKGPCRRIMGKAYHVPSGKILAVKVIPLDITVELQ 232

  Fly   128 KQILRELKVLHECNFPHIVGFYGAFYSDGEISICMEYMDGGSLDLILKRAGRIPESILGRITLAV 192
            :||:.||::|::|:..:|:||||||:.:..||||.|:|||||||:..|    |||.:||||.:||
Frog   233 RQIMSELEILYKCDSLYIIGFYGAFFVENRISICTEFMDGGSLDVYRK----IPEQVLGRIAVAV 293

  Fly   193 LKGLSYLRDNHAIIHRDVKPSNILVNSSGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGT 257
            ||||:||. :..|:||||||||:|||:.|.:|:||||||.||::|:|.::|||.:||:|||:.|.
Frog   294 LKGLTYLW-SLKILHRDVKPSNMLVNTRGHVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERIAGE 357

  Fly   258 HYSVQSDIWSLGLSLVEMAIGMYPIPPPNTATLESIFADNAEESGQPTDEPRAMAIFELLDYIVN 322
            .|.:.||:||||:|.:|:|:|.:|.|                   |......::...::|..||:
Frog   358 QYGIHSDVWSLGISFMELALGRFPYP-------------------QIQKNHGSLMPLQILQCIVD 403

  Fly   323 EPPPKLEHKIFSTEFKDFVDICLKKQPDERADLKTLLSHPWIRKAELEEVD-ISGWVCKTMD 383
            |..|.|....||..|..|:..|::|.|.||...:.|:.||:|.:......: :|.|||:.::
Frog   404 EECPVLPLGEFSESFVHFITQCMRKPPKERPAPEELMDHPFIVQFNDGNTEAVSMWVCRALE 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dsor1	NP_511098.1	PKc_MEK	85..382	CDD:132946	126/323 (39%)
Dsor1	NP_511098.1	S_TKc	88..364	CDD:214567	120/301 (40%)
map2k5	XP_017947570.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D566457at33208
OrthoFinder	1	1.000	-	-		FOG0000715
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X438
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010