DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dsor1 and Slik

DIOPT Version :9

Sequence 1:	NP_511098.1	Gene:	Dsor1 / 31872	FlyBaseID:	FBgn0010269	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_726441.1	Gene:	Slik / 37893	FlyBaseID:	FBgn0035001	Length:	1703	Species:	Drosophila melanogaster

Alignment Length:	386	Identity:	110/386 - (28%)
Similarity:	171/386 - (44%)	Gaps:	83/386 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 GDTERKRIKMFLSQKEKIGELSDEDLEKLGELGSGNGGVVMKVRHTHTHLIMARKLIHLEVKPAI 126
            |:.::||    |....|:.....|..|.:||||.|..|.|.|.:|.......|.|:..||.:..:
  Fly    16 GEAKKKR----LYNNIKMDTDPAEFWEMVGELGDGAFGKVYKAQHKEQKRFAAAKMCQLEDEENL 76

  Fly   127 KKQILRELKVLHECNFPHIVGFYGAFYSDGEISICMEYMDGGSLDLILKRAGR-IPESILGRITL 190
            ...:: |:.:|.|...|:||..|.||..|.::.:.:||.|||:||.|:....: :.|..:..:..
  Fly    77 SDHMV-EIDILSEIKHPNIVELYEAFSIDDKLWMLIEYCDGGALDSIMVELEKPLTEPQIAYVCK 140

  Fly   191 AVLKGLSYLRDNHAIIHRDVKPSNILVNSSGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSP-- 251
            .:.:||::|..| .:||||:|..|:|:...|.:|:.|||||.:...:|.  ::|:||..:|:|
  Fly   141 HMTEGLTFLHRN-KVIHRDLKAGNVLLTMEGGVKLADFGVSAKNKHTMQKHDTFIGTPYWMAPEL 204

  Fly   252 ---ERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPNTATLESIFADNAEESGQPTDEPRAMAI 313
               |..:...|..:.||||||::|:|:|    .:.|||:                      .|:.
  Fly   205 VLCETFRDNPYDHKVDIWSLGITLIELA----QMEPPNS----------------------EMSP 243

  Fly   314 FELLDYIVNEPPPKLEH-KIFSTEFKDFVDICLKKQPDERADLKTLLSHPWIR------------ 365
            ..:|..|....|||||. ..:|.||.||:...|.|.|..|.....|:.|.:|.
  Fly   244 MRVLLKIQKSEPPKLEQPSRWSKEFNDFLKKSLVKDPQVRPTTDVLMQHAFINRNLDAKPIKDLL 308

  Fly   366 ---KAE-LEEV-------------------DISGWVCKTMDLPPSTP-------KRNTSPN 396
               ||| :|||                   |.:....:.:|..|.||       |..:.|:
  Fly   309 LEYKAEVVEEVVDDETEEPRNSALQLDLDDDSASLQSQDIDKLPGTPTSILRDAKEQSQPS 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dsor1	NP_511098.1	PKc_MEK	85..382	CDD:132946	99/340 (29%)
Dsor1	NP_511098.1	S_TKc	88..364	CDD:214567	90/284 (32%)
Slik	NP_726441.1	STKc_SLK_like	31..310	CDD:132942	92/306 (30%)
		S_TKc	37..295	CDD:214567	90/285 (32%)
		PKK	958..1095	CDD:289257
		PKK	1126..1266	CDD:289257
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910