DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dsor1 and byr1

DIOPT Version :9

Sequence 1:	NP_511098.1	Gene:	Dsor1 / 31872	FlyBaseID:	FBgn0010269	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_593026.1	Gene:	byr1 / 2542137	PomBaseID:	SPAC1D4.13	Length:	340	Species:	Schizosaccharomyces pombe

Alignment Length:	299	Identity:	142/299 - (47%)
Similarity:	195/299 - (65%)	Gaps:	23/299 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 IGELSDEDLEKLGELGSGNGGVVMKVRHTHTHLIMARKLIHLEVKPAIKKQILRELKVLHECNFP 143
            |.:|.:..||.:..||.||||.|..|:  |.::.||||.:::.....::|||||||.|||.|..|
pombe    58 ISDLDNSSLEVVRHLGEGNGGAVSLVK--HRNIFMARKTVYVGSDSKLQKQILRELGVLHHCRSP 120

  Fly   144 HIVGFYGAFYSDGEISICMEYMDGGSLDLILKRAGRIPESILGRITLAVLKGLSYLRDNHAIIHR 208
            :||||||||.....||:||||||.||||.||:..|.||..|||:|..:::|||.||.:...||||
pombe   121 YIVGFYGAFQYKNNISLCMEYMDCGSLDAILREGGPIPLDILGKIINSMVKGLIYLYNVLHIIHR 185

  Fly   209 DVKPSNILVNSSGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLV 273
            |:||||::|||.||||:|||||||:|::|:|.:||||.:||||||::|..|:|:|||||||:|::
pombe   186 DLKPSNVVVNSRGEIKLCDFGVSGELVNSVAQTFVGTSTYMSPERIRGGKYTVKSDIWSLGISII 250

  Fly   274 EMAIGMYPIPPPNTATLESIFADNAEESGQPTDEPRAMAIFELLDYIVNEPPPKLEHKIFSTEFK 338
            |:|          |..|...|: |.::|         :.|.:||..||.|.||:|... |..:.:
pombe   251 ELA----------TQELPWSFS-NIDDS---------IGILDLLHCIVQEEPPRLPSS-FPEDLR 294

  Fly   339 DFVDICLKKQPDERADLKTLLSHPWIRKAELEEVDISGW 377
            .|||.||.|.|..||..:.|.:.|:.::|.:..||::.|
pombe   295 LFVDACLHKDPTLRASPQQLCAMPYFQQALMINVDLASW 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dsor1	NP_511098.1	PKc_MEK	85..382	CDD:132946	140/293 (48%)
Dsor1	NP_511098.1	S_TKc	88..364	CDD:214567	135/275 (49%)
byr1	NP_593026.1	PKc_Byr1_like	60..334	CDD:270792	141/297 (47%)
byr1	NP_593026.1	Pkinase	66..320	CDD:278497	136/276 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	243	1.000	Domainoid score	I440
eggNOG	1	0.900	-	-		E1_KOG0581
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2063
Inparanoid	1	1.050	258	1.000	Inparanoid score	I754
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000715
OrthoInspector	1	1.000	-	-		oto100564
orthoMCL	1	0.900	-	-		OOG6_100914
Panther	1	1.100	-	-	LDO	PTHR48013
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2221
SonicParanoid	1	1.000	-	-		X438
TreeFam	1	0.960	-	-
	13	12.850