DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dsor1 and Map2k6

DIOPT Version :9

Sequence 1:	NP_511098.1	Gene:	Dsor1 / 31872	FlyBaseID:	FBgn0010269	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_446155.1	Gene:	Map2k6 / 114495	RGDID:	620666	Length:	334	Species:	Rattus norvegicus

Alignment Length:	363	Identity:	128/363 - (35%)
Similarity:	190/363 - (52%)	Gaps:	60/363 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 PTPPFKTPSGTDTHSLLGKPKTSIDALTETLEGLDMGDTERKRIKMFLSQKEKIGELSDEDLEKL 90
            |...|:.|..:.|      |...:|:                  |..:|...:..|:..:|||.:
  Rat    16 PREAFEQPQTSST------PPRDLDS------------------KACISIGNQNFEVKADDLEPI 56

  Fly    91 GELGSGNGGVVMKVRHTHTHLIMARKLIHLEVKPAIKKQILRELKV-LHECNFPHIVGFYGAFYS 154
            .|||.|..|||.|:||..:..|||.|.|...|....:|::|.:|.| :...:.|..|.||||.:.
  Rat    57 VELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDVSMRTVDCPFTVTFYGALFR 121

  Fly   155 DGEISICMEYMDGGSLD----LILKRAGRIPESILGRITLAVLKGLSYLRDNHAIIHRDVKPSNI 215
            :|::.||||.|| .|||    .::.:...|||.|||:|.::::|.|.:|....::|||||||||:
  Rat   122 EGDVWICMELMD-TSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNV 185

  Fly   216 LVNSSGEIKICDFGVSGQLIDSMANSF-VGTRSYMSPER----LQGTHYSVQSDIWSLGLSLVEM 275
            |:|:.|::|:||||:||.|:||:|.:. .|.:.||:|||    |....|||:|||||||::::|:
  Rat   186 LINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIEL 250

  Fly   276 AIGMYPIPPPNTATLESIFADNAEESGQPTDEPRAMAIFELLDYIVNEPPPKLEHKIFSTEFKDF 340
            ||..:|.                :..|.|         |:.|..:|.||.|:|....||.:|.||
  Rat   251 AILRFPY----------------DSWGTP---------FQQLKQVVEEPSPQLPADKFSADFVDF 290

  Fly   341 VDICLKKQPDERADLKTLLSHPWIRKAELEEVDISGWV 378
            ...||||...||.....|:.||:....|.:..|::.:|
  Rat   291 TSQCLKKNSKERPTYPELMQHPFFTVHEAKAADVASFV 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dsor1	NP_511098.1	PKc_MEK	85..382	CDD:132946	119/304 (39%)
Dsor1	NP_511098.1	S_TKc	88..364	CDD:214567	114/285 (40%)
Map2k6	NP_446155.1	PKc_MKK3_6	51..333	CDD:173729	119/304 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D688282at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920