DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dsor1 and stk39

DIOPT Version :9

Sequence 1:	NP_511098.1	Gene:	Dsor1 / 31872	FlyBaseID:	FBgn0010269	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	XP_017953089.2	Gene:	stk39 / 100488948	XenbaseID:	XB-GENE-1012528	Length:	609	Species:	Xenopus tropicalis

Alignment Length:	319	Identity:	91/319 - (28%)
Similarity:	148/319 - (46%)	Gaps:	57/319 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 LGSGNGGVVMKVRHTHTHLIMARKLIHLEVKPAIKKQILRELKVLHECNFPHIVGFYGAFYSDGE 157
            :|||...||...........:|.|.|:||.......::|:|::.:.:|:.|:||.:|.:|....|
Frog   134 IGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNIVTYYTSFVVKEE 198

  Fly   158 ISICMEYMDGGS-LDLILKRAGR-------IPESILGRITLAVLKGLSYLRDNHAIIHRDVKPSN 214
            :.:.|:.:.||| ||:|....||       :.|||:..|...||:||.||..| ..||||:|..|
Frog   199 LWLVMKLLSGGSMLDIIKHVVGRGEHKNGVLEESIIATILKEVLEGLDYLHRN-GQIHRDLKAGN 262

  Fly   215 ILVNSSGEIKICDFGVSGQLI-------DSMANSFVGTRSYMSPERLQGTH-YSVQSDIWSLGLS 271
            ||:...|.::|.|||||..|.       :.:..:||||..:|:||.::... |..::|:||.|::
Frog   263 ILLGEDGSVQIADFGVSSFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGIT 327

  Fly   272 LVEMAIGMYP---IPPPNTATLESIFADNAEESGQPTDEPRAMAIFELLDYIVNEPPPKLEHKI- 332
            .:|:|.|..|   .||                             .::|...:...||.||..:
Frog   328 AIELATGAAPYHKYPP-----------------------------MKVLMLTLQNDPPTLETGVE 363

  Fly   333 -------FSTEFKDFVDICLKKQPDERADLKTLLSHPWIRKAELEEVDISGWVCKTMDL 384
                   :...|:..:.:||:|.|.:|.....||...:.:|::..|..|...:.||.::
Frog   364 DKEMMRKYGKSFRKLISLCLQKDPSKRPTAAELLKCKFFQKSKNREYLIEKLLIKTPNI 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dsor1	NP_511098.1	PKc_MEK	85..382	CDD:132946	90/315 (29%)
Dsor1	NP_511098.1	S_TKc	88..364	CDD:214567	86/297 (29%)
stk39	XP_017953089.2	STKc_OSR1_SPAK	126..402	CDD:270787	86/297 (29%)
stk39	XP_017953089.2	OSR1_C	516..573	CDD:403428
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D688282at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920