DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dsor1 and map2k5

DIOPT Version :9

Sequence 1:	NP_511098.1	Gene:	Dsor1 / 31872	FlyBaseID:	FBgn0010269	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_001107789.1	Gene:	map2k5 / 100007679	ZFINID:	ZDB-GENE-030131-1517	Length:	450	Species:	Danio rerio

Alignment Length:	368	Identity:	141/368 - (38%)
Similarity:	219/368 - (59%)	Gaps:	35/368 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 KTPSGTDTHSLL--GKPKTSIDALTETLEGLDMGDTERK---RIKMFLSQKEKIGELSDEDLEKL 90
            |||...:.|.|.  .:|::|....:...:......:.:|   .:|..|:.    |::::.||:..
Zfish   109 KTPGIRNIHGLKVNTRPESSSGRSSSAADSRSSDSSLKKSSAELKKILTN----GQINEHDLQYQ 169

  Fly    91 GELGSGNGGVVMKVRHTHTHLIMARKLIHLEVKPAIKKQILRELKVLHECNFPHIVGFYGAFYSD 155
            .:||.||||.|.|..|.....|:|.|:|.|::...::|||:.||::|::|:.|:|:.||.||:.:
Zfish   170 EQLGHGNGGTVYKAYHLLGKRIVAVKVIPLDITVELQKQIMSELEILYKCDSPYIIKFYSAFFVE 234

  Fly   156 GEISICMEYMDGGSLDLILKRAGRIPESILGRITLAVLKGLSYLRDNHAIIHRDVKPSNILVNSS 220
            ..||||.|:|||||||:.    .||||.:||||.:||:|||:||. :..|:||||||||:|||:.
Zfish   235 NRISICTEFMDGGSLDVY----WRIPEHVLGRIAVAVVKGLTYLW-SLKILHRDVKPSNMLVNTR 294

  Fly   221 GEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPP 285
            |::|:||||||.||::|:|.::|||.:||:|||:.|..|.:.||:||:|:|.:|:|:|.:|.|
Zfish   295 GQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSVGISFMELALGSFPYP-- 357

  Fly   286 NTATLESIFADNAEESGQPTDEPRAMAIFELLDYIVNEPPPKLEHKIFSTEFKDFVDICLKKQPD 350
                             |......::...:||..||:|.||.|....||.:|..|:..|::|.|.
Zfish   358 -----------------QIQKNQGSLMPLQLLQCIVDEDPPVLPVGQFSEKFVHFITQCMRKLPK 405

  Fly   351 ERADLKTLLSHPWIRKAELEEVD-ISGWVCKTM-DLPPSTPKR 391
            ||.....|:.||:|.:......: :|.|||::: |.....|:|
Zfish   406 ERPAPNNLMDHPFIVQYNDGNTEVVSMWVCRSLEDRKAQQPQR 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dsor1	NP_511098.1	PKc_MEK	85..382	CDD:132946	127/297 (43%)
Dsor1	NP_511098.1	S_TKc	88..364	CDD:214567	120/275 (44%)
map2k5	NP_001107789.1	PB1_Map2k5	17..106	CDD:99717
		PKc_MKK5	164..442	CDD:132950	128/301 (43%)
		S_TKc	170..419	CDD:214567	120/272 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0581
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D566457at33208
OrthoFinder	1	1.000	-	-		FOG0000715
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X438
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820