DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG42726 and Zkscan8

DIOPT Version :9

Sequence 1:	NP_732017.3	Gene:	CG42726 / 318709	FlyBaseID:	FBgn0261679	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	NP_631880.2	Gene:	Zkscan8 / 93681	MGIID:	1913815	Length:	588	Species:	Mus musculus

Alignment Length:	228	Identity:	71/228 - (31%)
Similarity:	114/228 - (50%)	Gaps:	4/228 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 RIIVTDKGYHCTVCNKDFRSRTQQYYHLTCGNDLLKKFNCKECGRRFATSSHLKYHLMSHEKQSK 128
            ||...:|.|.||||.|.|..|:....|....|. :|:::|||||:.|:.::.|..|...|..:..
Mouse   352 RIHTGEKPYQCTVCGKAFSYRSALLSHQDIHNK-VKRYHCKECGKAFSQNTGLILHQRIHTGEKP 415

  Fly   129 HSCSVCHKSFKQPIVLQRHMLTHNQEK-HLCPICQKVFRRKSSLASHLAIHSDLGLQFKCELCSK 192
            :.|:.|.|:|.|...|..|...|:.|: :.|..|.|.|...|.|..|..||:. ...::|:.|.|
Mouse   416 YQCNQCGKAFSQSAGLILHQRIHSGERPYECNECGKAFSHSSHLIGHQRIHTG-EKPYECDECGK 479

  Fly   193 HFQNKANLNQHLRKHDKNNIRHMCKVCQKSFLRQTTLRLHMKRHSNRERQSCSLCGKSYNDPDAL 257
            .|:..::|..|.|.|.... .:.|..|.::|.:::.|..|.:.|:......|..|||::|....|
Mouse   480 TFRRSSHLIGHQRSHTGEK-PYKCNECGRAFSQKSGLIEHQRIHTGERPYKCKECGKAFNGNTGL 543

  Fly   258 GRHLRQHKTAERYRCIQCDITINRKDNMLRHLR 290
            .:|||.|...:.|:|.:|.....::.:::||.|
Mouse   544 IQHLRIHTGEKPYQCSECRKAFIQRSSLIRHQR 576

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42726	NP_732017.3	C2H2 Zn finger	74..94	CDD:275368	8/19 (42%)
		C2H2 Zn finger	103..123	CDD:275368	8/19 (42%)
		COG5048	<112..288	CDD:227381	48/176 (27%)
		C2H2 Zn finger	131..151	CDD:275368	7/19 (37%)
		Chordopox_A33R	151..>254	CDD:283591	30/103 (29%)
		C2H2 Zn finger	158..178	CDD:275368	7/19 (37%)
		C2H2 Zn finger	187..207	CDD:275368	7/19 (37%)
		C2H2 Zn finger	216..236	CDD:275368	5/19 (26%)
		C2H2 Zn finger	244..264	CDD:275368	9/19 (47%)
		C2H2 Zn finger	272..290	CDD:275368	4/17 (24%)
Zkscan8	NP_631880.2	SCAN	48..158	CDD:128708
		KRAB_A-box	233..268	CDD:143639
		COG5048	<322..574	CDD:227381	68/224 (30%)
		C2H2 Zn finger	334..354	CDD:275368	1/1 (100%)
		C2H2 Zn finger	363..382	CDD:275368	7/18 (39%)
		C2H2 Zn finger	390..410	CDD:275368	8/19 (42%)
		C2H2 Zn finger	418..438	CDD:275368	7/19 (37%)
		C2H2 Zn finger	446..466	CDD:275368	7/19 (37%)
		C2H2 Zn finger	474..494	CDD:275368	7/19 (37%)
		C2H2 Zn finger	502..522	CDD:275368	5/19 (26%)
		C2H2 Zn finger	530..550	CDD:275368	9/19 (47%)
		C2H2 Zn finger	558..578	CDD:275368	5/19 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23226
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100