DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG42726 and Zkscan3

DIOPT Version :9

Sequence 1:NP_732017.3 Gene:CG42726 / 318709 FlyBaseID:FBgn0261679 Length:441 Species:Drosophila melanogaster
Sequence 2:NP_001139250.1 Gene:Zkscan3 / 72739 MGIID:1919989 Length:553 Species:Mus musculus


Alignment Length:242 Identity:71/242 - (29%)
Similarity:108/242 - (44%) Gaps:32/242 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    51 ETQETQARTSADKRIIVTDKGYHCTVCNKDF--RSRTQQYYHLTCGNDLLKKFNCKECGRRFATS 113
            |..|.:.:..|.::.....:.::|..|.|.|  .|...::..:..|   ||.:.|:|||:.|..|
Mouse   292 EASEQEGKLQAAQKSATGTRRFYCRECGKSFAQSSGLSKHKRIHTG---LKPYECEECGKAFIGS 353

  Fly   114 SHLKYHLMSHEKQSKHSCSVCHKSFKQPIVLQRHMLTHNQEK-HLCPICQKVFRRKSSLASHLAI 177
            |.|..|...|..:..:.|..|.|:|.....|.:|..||..|| :.|..|.|.|.:..||..|..|
Mouse   354 SALIIHQRVHTGEKPYECEECGKAFSHSSDLIKHQRTHTGEKPYECDDCGKTFTQSCSLLEHHRI 418

  Fly   178 HSDLGLQFKCELCSKHFQNKANLNQHLRKH--DKN-------------------NIR----HMCK 217
            |:. ...::|.:|.|.|:..::|.:|.|.|  ||:                   ||.    :.|.
Mouse   419 HTG-EKPYQCNMCPKAFRRSSHLLRHQRTHTGDKDFFVPEPYWESQSRVESHWENIETPVSYQCN 482

  Fly   218 VCQKSFLRQTTLRLHMKRHSNRERQSCSLCGKSYNDPDALGRHLRQH 264
            .|::||.|.|:|..|.|.|:..:...|..|||.:..|..|.:|.|:|
Mouse   483 DCERSFSRITSLIEHQKVHTGEKPFECQTCGKGFTRPSYLIQHQRRH 529

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42726NP_732017.3 C2H2 Zn finger 74..94 CDD:275368 5/21 (24%)
C2H2 Zn finger 103..123 CDD:275368 9/19 (47%)
COG5048 <112..288 CDD:227381 55/179 (31%)
C2H2 Zn finger 131..151 CDD:275368 6/19 (32%)
Chordopox_A33R 151..>254 CDD:283591 38/128 (30%)
C2H2 Zn finger 158..178 CDD:275368 7/19 (37%)
C2H2 Zn finger 187..207 CDD:275368 7/19 (37%)
C2H2 Zn finger 216..236 CDD:275368 9/19 (47%)
C2H2 Zn finger 244..264 CDD:275368 8/19 (42%)
C2H2 Zn finger 272..290 CDD:275368
Zkscan3NP_001139250.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 28..49
SCAN 47..159 CDD:128708
KRAB_A-box 213..267 CDD:383038
zf-C2H2 313..335 CDD:333835 5/21 (24%)
C2H2 Zn finger 315..335 CDD:275368 5/19 (26%)
zf-H2C2_2 328..350 CDD:372612 7/24 (29%)
zf-C2H2 341..363 CDD:333835 9/21 (43%)
C2H2 Zn finger 343..363 CDD:275368 9/19 (47%)
COG5048 <367..514 CDD:227381 43/147 (29%)
C2H2 Zn finger 371..391 CDD:275368 6/19 (32%)
C2H2 Zn finger 399..419 CDD:275368 7/19 (37%)
C2H2 Zn finger 427..447 CDD:275368 7/19 (37%)
C2H2 Zn finger 481..501 CDD:275368 9/19 (47%)
zf-C2H2 507..529 CDD:333835 8/21 (38%)
C2H2 Zn finger 509..529 CDD:275368 8/19 (42%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR23226
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

Return to query results.
Submit another query.