DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42726 and Zfp110

DIOPT Version :9

Sequence 1:	NP_732017.3	Gene:	CG42726 / 318709	FlyBaseID:	FBgn0261679	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	NP_001347505.1	Gene:	Zfp110 / 65020	MGIID:	1890378	Length:	832	Species:	Mus musculus

Alignment Length:	178	Identity:	51/178 - (28%)
Similarity:	80/178 - (44%)	Gaps:	6/178 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 YYHLTCGNDLLKKFNCKECGRRFATSSHLKYHLMSHEKQSKHSCSVCHKSFKQPIVLQRHMLTHN 152
            ||.   |:|:.:......|.:.|:..:.....:..|:......||.|.|.|:.......|...|.
Mouse   650 YYR---GSDVGRLRRANNCRKAFSLHAQQISFIKIHKGSQVCRCSECGKLFRNARYFSVHKKIHT 711

  Fly   153 QEK-HLCPICQKVFRRKSSLASHLAIHSDLGLQFKCELCSKHFQNKANLNQHLRKHDKNNIRHMC 216
            .|: ::|..|.|.|.:.|||..||.|||. ...|:|..|.:.|.:::.::||||.|......| |
Mouse   712 GERPYMCMACGKAFVQSSSLTQHLRIHSG-ERPFECSECGRTFNDRSAISQHLRTHTGAKPYH-C 774

  Fly   217 KVCQKSFLRQTTLRLHMKRHSNRERQSCSLCGKSYNDPDALGRHLRQH 264
            :.|.|:|.:.:.|..|.:.|:......|..|||::.....|..|.:.|
Mouse   775 ERCGKAFRQSSHLTRHERTHTGERPYVCIKCGKAFTQSSHLIGHQKTH 822

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42726	NP_732017.3	C2H2 Zn finger	74..94	CDD:275368	2/5 (40%)
		C2H2 Zn finger	103..123	CDD:275368	2/19 (11%)
		COG5048	<112..288	CDD:227381	45/154 (29%)
		C2H2 Zn finger	131..151	CDD:275368	6/19 (32%)
		Chordopox_A33R	151..>254	CDD:283591	35/103 (34%)
		C2H2 Zn finger	158..178	CDD:275368	9/19 (47%)
		C2H2 Zn finger	187..207	CDD:275368	7/19 (37%)
		C2H2 Zn finger	216..236	CDD:275368	6/19 (32%)
		C2H2 Zn finger	244..264	CDD:275368	6/19 (32%)
		C2H2 Zn finger	272..290	CDD:275368
Zfp110	NP_001347505.1	KRAB	18..77	CDD:214630
		SCAN	159..246	CDD:307924
		KRAB	283..324	CDD:307490
		C2H2 Zn finger	663..682	CDD:275370	2/18 (11%)
		C2H2 Zn finger	690..710	CDD:275368	6/19 (32%)
		zf-H2C2_2	702..727	CDD:316026	7/24 (29%)
		C2H2 Zn finger	718..738	CDD:275368	9/19 (47%)
		zf-H2C2_2	730..754	CDD:316026	10/24 (42%)
		C2H2 Zn finger	746..766	CDD:275368	7/19 (37%)
		zf-C2H2	772..794	CDD:306579	7/22 (32%)
		C2H2 Zn finger	774..794	CDD:275368	6/19 (32%)
		zf-H2C2_2	786..811	CDD:316026	7/24 (29%)
		C2H2 Zn finger	802..822	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23226
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100