DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG42726 and Zfp951

DIOPT Version :9

Sequence 1:	NP_732017.3	Gene:	CG42726 / 318709	FlyBaseID:	FBgn0261679	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	XP_036021294.1	Gene:	Zfp951 / 626391	MGIID:	2441896	Length:	465	Species:	Mus musculus

Alignment Length:	293	Identity:	87/293 - (29%)
Similarity:	123/293 - (41%)	Gaps:	29/293 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 CNCDATGQNRLVTDSCGHT-KCRLCLVADVSDCLECRVARSVDIQETQETQARTSADKRIIVTDK 70
            |.|::..|:...||:..:. ||..|..|         .||..|:|..:.|.          ..:|
Mouse   171 CTCNSHLQSHKRTDTRENPYKCNHCGKA---------FARHRDLQNHERTH----------TGEK 216

  Fly    71 GYHCTVCNKDFRSRTQQYYH--LTCGNDLLKKFNCKECGRRFATSSHLKYHLMSHEKQSKHSCSV 133
            .|.|..|.|.|...:..:.|  ...|.   |.|.|.:||:.||..|||:.|..:|..:..:.|:.
Mouse   217 PYECKQCGKAFALNSYLHIHERTHTGE---KPFECSQCGKAFACHSHLQSHKRTHTGEKPYECNQ 278

  Fly   134 CHKSFKQPIVLQRHMLTHNQEK-HLCPICQKVFRRKSSLASHLAIHSDLGLQFKCELCSKHFQNK 197
            |.|:|.....||.|..||..|| :.|..|.|.|...|.|.||...|:. ...::|:.|.|.|...
Mouse   279 CGKAFSWNYCLQIHKRTHTGEKPYACNQCGKAFACHSHLQSHERTHTG-EKPYECDQCGKAFSWN 342

  Fly   198 ANLNQHLRKHDKNNIRHMCKVCQKSFLRQTTLRLHMKRHSNRERQSCSLCGKSYNDPDALGRHLR 262
            ..|..|.|.|.... .:.|..|.|:|...:.|:.|.|.|:..:...|..|||:::....|..|.|
Mouse   343 YCLQIHKRTHTGEK-PYECNQCGKAFACHSHLQRHEKTHTGEKPYECDQCGKAFSWNYCLQIHKR 406

  Fly   263 QHKTAERYRCIQCDITINRKDNMLRHLRSMHPG 295
            .|...:.|.|.||.....|..::..|.|: |.|
Mouse   407 THTGEKPYACNQCGKAFPRHHHLQNHERT-HTG 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42726	NP_732017.3	C2H2 Zn finger	74..94	CDD:275368	5/21 (24%)
		C2H2 Zn finger	103..123	CDD:275368	9/19 (47%)
		COG5048	<112..288	CDD:227381	54/176 (31%)
		C2H2 Zn finger	131..151	CDD:275368	7/19 (37%)
		Chordopox_A33R	151..>254	CDD:283591	32/103 (31%)
		C2H2 Zn finger	158..178	CDD:275368	8/19 (42%)
		C2H2 Zn finger	187..207	CDD:275368	7/19 (37%)
		C2H2 Zn finger	216..236	CDD:275368	7/19 (37%)
		C2H2 Zn finger	244..264	CDD:275368	7/19 (37%)
		C2H2 Zn finger	272..290	CDD:275368	5/17 (29%)
Zfp951	XP_036021294.1	KRAB	42..82	CDD:396083
		COG5048	<151..376	CDD:227381	67/228 (29%)
		C2H2 Zn finger	164..184	CDD:275368	3/12 (25%)
		C2H2 Zn finger	192..212	CDD:275368	7/28 (25%)
		C2H2 Zn finger	220..240	CDD:275368	5/19 (26%)
		C2H2 Zn finger	248..268	CDD:275368	9/19 (47%)
		C2H2 Zn finger	276..296	CDD:275368	7/19 (37%)
		COG5048	<300..453	CDD:227381	43/142 (30%)
		C2H2 Zn finger	304..324	CDD:275368	8/19 (42%)
		C2H2 Zn finger	332..352	CDD:275368	7/19 (37%)
		C2H2 Zn finger	360..380	CDD:275368	7/19 (37%)
		C2H2 Zn finger	388..408	CDD:275368	7/19 (37%)
		C2H2 Zn finger	416..436	CDD:275368	6/20 (30%)
		C2H2 Zn finger	444..464	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23226
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100