DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42726 and CG6813

DIOPT Version :9

Sequence 1:	NP_732017.3	Gene:	CG42726 / 318709	FlyBaseID:	FBgn0261679	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	NP_001163590.1	Gene:	CG6813 / 41396	FlyBaseID:	FBgn0037923	Length:	294	Species:	Drosophila melanogaster

Alignment Length:	297	Identity:	66/297 - (22%)
Similarity:	106/297 - (35%)	Gaps:	57/297 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 CRLCLVADVSDCLECRVARSVDI----------QETQETQARTSADKRIIVTDKGYHCTVCNKD- 80
            ||:|..:|.          .:|:          |....|....|..|.|    .|..||.|..:
  Fly     6 CRICSRSDA----------PIDLFGPGNGHLVRQIHSITGVELSCKKEI----SGQMCTTCLDNL 56

  Fly    81 -----FRSRTQQYYHLTCGNDLLKKFNC--KECGRRFATSSHLKYHLMSHEKQSKHSCSV-CHKS 137
                 ||.|.     :......|::..|  |:|    :|...:...:..::.:|:...|: |.:.
  Fly    57 QAAIKFRQRC-----IIAEKQNLERIECDSKDC----STDPIIYEDIDDNQIESELDESILCPEV 112

  Fly   138 FKQPI-----VLQRHMLTHNQE------KHLCPICQKVFRRKSSLASHLAIHSDLGLQFKCEL-- 189
            ...|:     |.....|.|.:.      .::||.|.::...||:...|...|:.: ..|.|..
  Fly   113 KDLPMPSAEKVSAPTSLNHQKSIGGGTGPYVCPDCGRIINNKSNFQEHTLRHTGI-KNFHCVFLN 176

  Fly   190 CSKHFQNKANLNQHLRKHDKNNIRHMCKVCQKSFLRQTTLRLHMKRHSNRERQSCSLCGKSYNDP 254
            |.:.|..:..|..|.|.|.... .::|..|.:.|......:.|.:||.|..|..|..|.||:...
  Fly   177 CERSFATRKELTSHTRIHTGEQ-PYVCVYCPRRFSSSGARQEHHRRHRNERRYECDTCKKSFVSS 240

  Fly   255 DALGRHLRQHKTAERYRCIQCDITINRKDNMLRHLRS 291
            ..|.:|...|..|..:.|..|.....|..:::.||.|
  Fly   241 GCLRKHKMIHVDARNHYCYVCQKHFKRISHLMTHLSS 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42726	NP_732017.3	C2H2 Zn finger	74..94	CDD:275368	6/25 (24%)
		C2H2 Zn finger	103..123	CDD:275368	4/21 (19%)
		COG5048	<112..288	CDD:227381	42/189 (22%)
		C2H2 Zn finger	131..151	CDD:275368	5/25 (20%)
		Chordopox_A33R	151..>254	CDD:283591	28/110 (25%)
		C2H2 Zn finger	158..178	CDD:275368	6/19 (32%)
		C2H2 Zn finger	187..207	CDD:275368	6/21 (29%)
		C2H2 Zn finger	216..236	CDD:275368	4/19 (21%)
		C2H2 Zn finger	244..264	CDD:275368	6/19 (32%)
		C2H2 Zn finger	272..290	CDD:275368	4/17 (24%)
CG6813	NP_001163590.1	zf-AD	6..76	CDD:285071	18/88 (20%)
		C2H2 Zn finger	144..164	CDD:275368	6/19 (32%)
		C2H2 Zn finger	172..194	CDD:275368	6/21 (29%)
		zf-H2C2_2	186..211	CDD:290200	7/25 (28%)
		UFD2	<256..>294	CDD:227443	6/22 (27%)
		C2H2 Zn finger	258..280	CDD:275368	6/20 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468422
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930