DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42726 and ZKSCAN4

DIOPT Version :9

Sequence 1:NP_732017.3 Gene:CG42726 / 318709 FlyBaseID:FBgn0261679 Length:441 Species:Drosophila melanogaster
Sequence 2:NP_061983.2 Gene:ZKSCAN4 / 387032 HGNCID:13854 Length:545 Species:Homo sapiens


Alignment Length:243 Identity:64/243 - (26%)
Similarity:101/243 - (41%) Gaps:33/243 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    51 ETQETQARTSADKRIIVTDKGYHCTVCNKDF--RSRTQQYYHLTCGNDLLKKFNCKECGRRFATS 113
            |..|.:.|....::..:..:.::|..|.|.|  .|...::..:..|.   |.:.|::||:.|..|
Human   299 EAGEQEGRLQRKQKNAIGSRRHYCHECGKSFAQSSGLTKHRRIHTGE---KPYECEDCGKTFIGS 360

  Fly   114 SHLKYHLMSHEKQSKHSCSVCHKSFKQPIVLQRHMLTHNQEK-HLCPICQKVFRRKSSLASHLAI 177
            |.|..|...|..:..:.|..|.|.|.....|.:|..||..|| :.|..|.|.|.:..||..|..|
Human   361 SALVIHQRVHTGEKPYECEECGKVFSHSSNLIKHQRTHTGEKPYECDDCGKTFSQSCSLLEHHKI 425

  Fly   178 HSDLGLQFKCELCSKHFQNKANLNQHLRKHDKNNIR--------------------------HMC 216
            |:. ...::|.:|.|.|:..::|.:|.|.|...|::                          :.|
Human   426 HTG-EKPYQCNMCGKAFRRNSHLLRHQRIHGDKNVQNPEHGESWESQGRTESQWENTEAPVSYKC 489

  Fly   217 KVCQKSFLRQTTLRLHMKRHSNRERQSCSLCGKSYNDPDALGRHLRQH 264
            ..|::||.|..:|..|.|.|:..:...|..|||.:.....|.:|.|.|
Human   490 NECERSFTRNRSLIEHQKIHTGEKPYQCDTCGKGFTRTSYLVQHQRSH 537

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42726NP_732017.3 C2H2 Zn finger 74..94 CDD:275368 5/21 (24%)
C2H2 Zn finger 103..123 CDD:275368 8/19 (42%)
COG5048 <112..288 CDD:227381 50/180 (28%)
C2H2 Zn finger 131..151 CDD:275368 6/19 (32%)
Chordopox_A33R 151..>254 CDD:283591 34/129 (26%)
C2H2 Zn finger 158..178 CDD:275368 7/19 (37%)
C2H2 Zn finger 187..207 CDD:275368 7/19 (37%)
C2H2 Zn finger 216..236 CDD:275368 8/19 (42%)
C2H2 Zn finger 244..264 CDD:275368 7/19 (37%)
C2H2 Zn finger 272..290 CDD:275368
ZKSCAN4NP_061983.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..22
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 34..55
SCAN 49..160 CDD:128708
KRAB 221..281 CDD:214630
zf-C2H2 320..342 CDD:306579 5/21 (24%)
C2H2 Zn finger 322..342 CDD:275368 5/19 (26%)
zf-H2C2_2 335..357 CDD:316026 5/24 (21%)
C2H2 Zn finger 350..370 CDD:275368 8/19 (42%)
COG5048 <374..544 CDD:227381 45/165 (27%)
C2H2 Zn finger 378..398 CDD:275368 6/19 (32%)
C2H2 Zn finger 406..426 CDD:275368 7/19 (37%)
C2H2 Zn finger 434..454 CDD:275368 7/19 (37%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 455..480 1/24 (4%)
C2H2 Zn finger 489..509 CDD:275368 8/19 (42%)
C2H2 Zn finger 517..537 CDD:275368 7/19 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR23226
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

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