DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42726 and Zfp174

DIOPT Version :9

Sequence 1:	NP_732017.3	Gene:	CG42726 / 318709	FlyBaseID:	FBgn0261679	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	NP_001074686.1	Gene:	Zfp174 / 385674	MGIID:	2686600	Length:	407	Species:	Mus musculus

Alignment Length:	172	Identity:	46/172 - (26%)
Similarity:	73/172 - (42%)	Gaps:	25/172 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 ETQARTSADKRII------------VTDKGYHCTVCNKDFRSRTQQYYHLTCGNDLLKKFNCKEC 106
            |.:..|::|.|::            :.....||         |..:|.........|::......
Mouse   246 EPRGVTASDARLLQWQVRPPQSPKSLAHYQKHC---------RELEYISNPLRGHPLRELKRSRG 301

  Fly   107 GRRFATSSHLKY--HLMSHEKQSKHSCSVCHKSFKQPIVLQRHMLTHNQEK-HLCPICQKVFRRK 168
            |||.:.|..|:.  |..:|..:..:||..|.|:|.....|:||...|..|: ::|..|...|.|:
Mouse   302 GRRRSLSGLLQCLGHQAAHPAKKPYSCEDCGKNFTWNSELKRHRRVHTGERPYICGECGNCFGRQ 366

  Fly   169 SSLASHLAIHSDLGLQFKCELCSKHFQNKANLNQHLRKHDKN 210
            |:|..|..||:. ...::|..|.|.|:..:||:||.|.|..|
Mouse   367 STLKLHQRIHTG-EKPYQCSHCGKCFRQSSNLHQHHRLHHGN 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42726	NP_732017.3	C2H2 Zn finger	74..94	CDD:275368	3/19 (16%)
		C2H2 Zn finger	103..123	CDD:275368	6/21 (29%)
		COG5048	<112..288	CDD:227381	34/102 (33%)
		C2H2 Zn finger	131..151	CDD:275368	7/19 (37%)
		Chordopox_A33R	151..>254	CDD:283591	22/61 (36%)
		C2H2 Zn finger	158..178	CDD:275368	7/19 (37%)
		C2H2 Zn finger	187..207	CDD:275368	9/19 (47%)
		C2H2 Zn finger	216..236	CDD:275368
		C2H2 Zn finger	244..264	CDD:275368
		C2H2 Zn finger	272..290	CDD:275368
Zfp174	NP_001074686.1	SCAN	42..152	CDD:128708
		SCAN	42..130	CDD:280241
		C2H2 Zn finger	328..348	CDD:275368	7/19 (37%)
		zf-H2C2_2	340..365	CDD:290200	8/24 (33%)
		COG5048	352..>407	CDD:227381	19/55 (35%)
		C2H2 Zn finger	356..376	CDD:275368	7/19 (37%)
		zf-H2C2_2	369..393	CDD:290200	8/24 (33%)
		C2H2 Zn finger	384..404	CDD:275368	9/19 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23226
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100