DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42726 and CG12605

DIOPT Version :9

Sequence 1:	NP_732017.3	Gene:	CG42726 / 318709	FlyBaseID:	FBgn0261679	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	NP_001261387.1	Gene:	CG12605 / 38468	FlyBaseID:	FBgn0035481	Length:	619	Species:	Drosophila melanogaster

Alignment Length:	177	Identity:	57/177 - (32%)
Similarity:	88/177 - (49%)	Gaps:	17/177 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 HLTCGN--DLLKK----FNCKECGRRFATSSHLKYHLMSH---EKQSKHSCSVCHKSFKQPIVLQ 145
            |.:.||  :..|:    :.|.|||:::||||:|..|..:|   :.||...|:.|.|::.....|.
  Fly   422 HSSSGNGENYAKRKRGCYKCCECGKQYATSSNLSRHKQTHRSLDSQSAKKCNTCGKAYVSMPALA 486

  Fly   146 RHMLTHNQEKHLCPICQKVFRRKSSLASHLAIHSDLGLQFKCELCSKHFQNKANLNQHLRKH--D 208
            .|:||| :..|.|.||.|:|.|...|..||..|:. ...:.|..|.|.|.:::||..|::.|  |
  Fly   487 MHLLTH-KLSHSCDICGKLFSRPWLLQGHLRSHTG-EKPYACVHCGKAFADRSNLRAHMQTHSGD 549

  Fly   209 KNNIRHMCKVCQKSFLRQTTLRLHMKRHSNRERQSCSLCGKSYNDPD 255
            ||   ..|..|.|:|..::.|..|::....|:..:... ||...:.|
  Fly   550 KN---FKCHRCNKTFALKSYLNKHLESACLRDAGAIDQ-GKGLEEED 592

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42726	NP_732017.3	C2H2 Zn finger	74..94	CDD:275368	1/3 (33%)
		C2H2 Zn finger	103..123	CDD:275368	10/19 (53%)
		COG5048	<112..288	CDD:227381	48/149 (32%)
		C2H2 Zn finger	131..151	CDD:275368	6/19 (32%)
		Chordopox_A33R	151..>254	CDD:283591	32/104 (31%)
		C2H2 Zn finger	158..178	CDD:275368	9/19 (47%)
		C2H2 Zn finger	187..207	CDD:275368	7/19 (37%)
		C2H2 Zn finger	216..236	CDD:275368	6/19 (32%)
		C2H2 Zn finger	244..264	CDD:275368	3/12 (25%)
		C2H2 Zn finger	272..290	CDD:275368
CG12605	NP_001261387.1	zf-C2H2	439..461	CDD:278523	10/21 (48%)
		C2H2 Zn finger	441..461	CDD:275370	10/19 (53%)
		C2H2 Zn finger	472..492	CDD:275368	6/19 (32%)
		COG5048	492..>570	CDD:227381	28/82 (34%)
		zf-C2H2	496..518	CDD:278523	10/21 (48%)
		C2H2 Zn finger	498..518	CDD:275368	9/19 (47%)
		zf-H2C2_2	511..534	CDD:290200	7/23 (30%)
		zf-C2H2	524..546	CDD:278523	7/21 (33%)
		C2H2 Zn finger	526..546	CDD:275368	7/19 (37%)
		zf-H2C2_2	538..562	CDD:290200	10/26 (38%)
		C2H2 Zn finger	554..571	CDD:275368	5/16 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457103
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23226
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030