DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42726 and CG11906

DIOPT Version :9

Sequence 1:	NP_732017.3	Gene:	CG42726 / 318709	FlyBaseID:	FBgn0261679	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	NP_611402.2	Gene:	CG11906 / 37209	FlyBaseID:	FBgn0034425	Length:	634	Species:	Drosophila melanogaster

Alignment Length:	214	Identity:	54/214 - (25%)
Similarity:	83/214 - (38%)	Gaps:	39/214 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 LKKFNC--KECGRRFAT-SSHLKYHLMSHEKQSKHSCSVCHKSFKQPIVLQRHMLTHNQEKHLCP 159
            ||.|.|  .:||.:..| .:.:|:..|.|.|.|...|..|...|...:.|..||...|:..::|.
  Fly   441 LKSFTCFTPDCGYQTDTLVALMKHDYMEHWKMSWFYCHKCGDVFTSKVFLDYHMHLQNRGLYICH 505

  Fly   160 ICQKVFRRKSSLASHLAIHSDLGLQFKCELCSKHFQNKANLNQHLRK--HDKNNIRHMCKVCQKS 222
            .|::.|..:..|..|..:|.. |:.:.|..|...|.::|.|..|.:|  |..|: ..:..: .:|
  Fly   506 KCREEFELQHQLDRHFQLHRK-GINYHCNFCRLEFLSEAKLLAHCKKLGHSPND-EPLISI-DRS 567

  Fly   223 FLRQTTLRLHMKRHSNRERQSCSLCGKSYND----------PDALGRHLRQHKTAERYRCIQCDI 277
            .   :.:..|:.|.|:..|     ..|||.:          |.....||.|||.. |:....||
  Fly   568 L---SIVNCHVPRSSDYSR-----IVKSYEEREFYIPRIPMPSTQPMHLPQHKPF-RFAIGICD- 622

  Fly   278 TINRKDNMLRHLRSMHPGC 296
                       ....:|.|
  Fly   623 -----------FEERNPNC 630

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42726	NP_732017.3	C2H2 Zn finger	74..94	CDD:275368
		C2H2 Zn finger	103..123	CDD:275368	6/22 (27%)
		COG5048	<112..288	CDD:227381	46/188 (24%)
		C2H2 Zn finger	131..151	CDD:275368	6/19 (32%)
		Chordopox_A33R	151..>254	CDD:283591	25/114 (22%)
		C2H2 Zn finger	158..178	CDD:275368	5/19 (26%)
		C2H2 Zn finger	187..207	CDD:275368	7/21 (33%)
		C2H2 Zn finger	216..236	CDD:275368	2/19 (11%)
		C2H2 Zn finger	244..264	CDD:275368	6/29 (21%)
		C2H2 Zn finger	272..290	CDD:275368	2/17 (12%)
CG11906	NP_611402.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468400
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930