DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42726 and Zfp422

DIOPT Version :9

Sequence 1:	NP_732017.3	Gene:	CG42726 / 318709	FlyBaseID:	FBgn0261679	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	NP_001012763.1	Gene:	Zfp422 / 360389	RGDID:	620229	Length:	237	Species:	Rattus norvegicus

Alignment Length:	219	Identity:	57/219 - (26%)
Similarity:	89/219 - (40%)	Gaps:	52/219 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 VARSVDIQETQETQARTS----------------ADKRIIVTDKGYHCTVCNKDFRSRTQQYYH- 90
            ::||....:|.|::.:|:                :.:|..|.:|.|.||.|:|.|...:..:.|
  Rat    10 ISRSASQGKTYESKRKTARQRQKWGVAIRFDSGLSRRRRNVDEKPYKCTKCSKSFSQSSTLFQHK 74

  Fly    91 -LTCGNDLLKKFNCKECGRRFATSSHLKYHLMSHEKQSKHSCSVCHKSFKQPIVLQRHMLTHNQE 154
             :..|.   |...|.:||:.|..||:|..|...|..:..:.|..|.:.|||...|.:|...|..|
  Rat    75 KIHTGK---KSHKCADCGKSFFQSSNLIQHRRIHTGEKPYKCDECGERFKQSSNLIQHQRIHTGE 136

  Fly   155 KHLCPICQKVFRRKSSLASHLAIHSDLGLQFKCELCSKHFQNKANLNQHLRKHDKNNIRHMCKVC 219
            |..|                            |:.|.:.|...::|.||.|.|.... .:.|:.|
  Rat   137 KPYC----------------------------CDECGRCFSQSSHLIQHQRTHTGEK-PYQCEEC 172

  Fly   220 QKSFLRQTTLRLHMKRHSNRERQS 243
            .|.|.:.:.||.|||.|  :|::|
  Rat   173 DKCFSQSSHLRQHMKVH--KEKKS 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42726	NP_732017.3	C2H2 Zn finger	74..94	CDD:275368	6/21 (29%)
		C2H2 Zn finger	103..123	CDD:275368	8/19 (42%)
		COG5048	<112..288	CDD:227381	36/132 (27%)
		C2H2 Zn finger	131..151	CDD:275368	7/19 (37%)
		Chordopox_A33R	151..>254	CDD:283591	24/93 (26%)
		C2H2 Zn finger	158..178	CDD:275368	1/19 (5%)
		C2H2 Zn finger	187..207	CDD:275368	7/19 (37%)
		C2H2 Zn finger	216..236	CDD:275368	9/19 (47%)
		C2H2 Zn finger	244..264	CDD:275368	57/219 (26%)
		C2H2 Zn finger	272..290	CDD:275368
Zfp422	NP_001012763.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..33		5/22 (23%)
		COG5048	<53..192	CDD:227381	48/172 (28%)
		C2H2 Zn finger	57..77	CDD:275368	6/19 (32%)
		C2H2 Zn finger	85..105	CDD:275368	8/19 (42%)
		C2H2 Zn finger	113..133	CDD:275368	7/19 (37%)
		C2H2 Zn finger	141..161	CDD:275368	7/19 (37%)
		C2H2 Zn finger	169..189	CDD:275368	9/19 (47%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	188..218		3/9 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23226
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100