DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42726 and esg

DIOPT Version :9

Sequence 1:	NP_732017.3	Gene:	CG42726 / 318709	FlyBaseID:	FBgn0261679	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	NP_476600.1	Gene:	esg / 34903	FlyBaseID:	FBgn0001981	Length:	470	Species:	Drosophila melanogaster

Alignment Length:	213	Identity:	66/213 - (30%)
Similarity:	102/213 - (47%)	Gaps:	32/213 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 PRCNCDATGQNRLVTDSCGHTKCRLCLVADVSDCLECRVARSVDIQETQETQARTSADKRIIVTD 69
            |..:|.::....|   |..|....|.|  :.|...|...|::.|:  :.||....||.|     |
  Fly   250 PESSCSSSLPEDL---SLKHKNLNLNL--NTSQPGEQAAAKTGDM--SPETMPNASAKK-----D 302

  Fly    70 KG----YHCTVCNKDFR-----SRTQQYYHLTC----GNDLLKKFNCKECGRRFATSSHLKYHLM 121
            |.    |.|..|.|.:.     ::.||::   |    ||.:.|.|:||:|.:.:.:...||.|:.
  Fly   303 KNQPPRYQCPDCQKSYSTFSGLTKHQQFH---CPAAEGNQVKKSFSCKDCDKTYVSLGALKMHIR 364

  Fly   122 SHEKQSKHSCSVCHKSFKQPIVLQRHMLTHNQEKHL-CPICQKVFRRKSSLASHLAIHSDLGLQF 185
            :|....|  |::|.|:|.:|.:||.|:.||..||.. |..|.:.|..:|:|.:||..|||: .::
  Fly   365 THTLPCK--CNLCGKAFSRPWLLQGHIRTHTGEKPFSCQHCHRAFADRSNLRAHLQTHSDI-KKY 426

  Fly   186 KCELCSKHFQNKANLNQH 203
            .|..|||.|...:.|.:|
  Fly   427 SCTSCSKTFSRMSLLTKH 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42726	NP_732017.3	C2H2 Zn finger	74..94	CDD:275368	6/28 (21%)
		C2H2 Zn finger	103..123	CDD:275368	6/19 (32%)
		COG5048	<112..288	CDD:227381	34/93 (37%)
		C2H2 Zn finger	131..151	CDD:275368	8/19 (42%)
		Chordopox_A33R	151..>254	CDD:283591	20/54 (37%)
		C2H2 Zn finger	158..178	CDD:275368	7/19 (37%)
		C2H2 Zn finger	187..207	CDD:275368	7/17 (41%)
		C2H2 Zn finger	216..236	CDD:275368
		C2H2 Zn finger	244..264	CDD:275368
		C2H2 Zn finger	272..290	CDD:275368
esg	NP_476600.1	zf-C2H2	309..331	CDD:278523	6/21 (29%)
		C2H2 Zn finger	311..331	CDD:275370	5/19 (26%)
		zf-C2H2	344..366	CDD:278523	7/21 (33%)
		C2H2 Zn finger	346..366	CDD:275368	6/19 (32%)
		zf-C2H2	370..392	CDD:278523	9/23 (39%)
		C2H2 Zn finger	372..392	CDD:275368	8/19 (42%)
		zf-H2C2_2	385..408	CDD:290200	9/22 (41%)
		zf-C2H2	398..420	CDD:278523	7/21 (33%)
		C2H2 Zn finger	400..420	CDD:275368	7/19 (37%)
		C2H2 Zn finger	428..444	CDD:275368	6/15 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468426
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840