DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42726 and zld

DIOPT Version :9

Sequence 1:	NP_732017.3	Gene:	CG42726 / 318709	FlyBaseID:	FBgn0261679	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	NP_001285466.1	Gene:	zld / 32994	FlyBaseID:	FBgn0259789	Length:	1596	Species:	Drosophila melanogaster

Alignment Length:	382	Identity:	82/382 - (21%)
Similarity:	135/382 - (35%)	Gaps:	90/382 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 RSVDIQETQE---TQARTSADKRIIVTDKGYHCTVC------NKDFRSRTQQYYHLTCGNDLLKK 100
            :.:|.|:.|:   .|.:|.|.:.:....:|.:.|..      |....|.:.....|..|     :
  Fly  1266 QQLDHQQQQQILADQTQTMAQQPLAKKRRGGNATPSTTKRRRNSSVGSTSPHSTTLPSG-----R 1325

  Fly   101 FNCKECGRRFATSSHLKYHLMSHEKQSKHSCSVCHKSFKQPIVLQRHMLTHNQE-KHLCPICQKV 164
            ..|.||.:.|..:.:|..|               :|||            |:.| ...|..|.|.
  Fly  1326 IKCLECDKEFTKNCYLTQH---------------NKSF------------HSGEYPFRCQKCGKR 1363

  Fly   165 FRRKSSLASHLAIHSDLGLQFKCELCSKHFQNKANLNQHLRKHDKNNIRHMCKVCQKSFLRQTTL 229
            |:.:....:||..|.......|||||.|.|.:|.:|.:|:........:|||.:|:|.|.|:..|
  Fly  1364 FQSEDVYTTHLGRHRTQDKPHKCELCPKQFHHKTDLRRHVEAIHTGLKQHMCDICEKGFCRKDHL 1428

  Fly   230 RLHMKRHSNRERQSCSLCGKSYNDPDALGRHLRQHKTAERYRCIQCDITINRKDNMLRHLRSMHP 294
            |.|::.|               |.|..:|:     |:|...........:.....:        .
  Fly  1429 RKHLETH---------------NRPRVVGK-----KSAAAAAAAAAAAAVTATAGL--------G 1465

  Fly   295 GCAFASTVEMVTPRSSAQEATTAEERPSQTVRYNSVIQSVGNVEPVMLLQSTPLPSQLPELQMEK 359
            |...|.:::....||....|.::|  |...|...|. .:.....||.:..|..:.:..|.|  ..
  Fly  1466 GAPAAGSIKAAFARSLTVTAVSSE--PGAGVAIPSA-PATATCAPVSVSASALVQAVNPSL--TS 1525

  Fly   360 GKAVPEHLPLPDVMPEENVQLYRKIILDLDNEEYSSEPSPD-------AQEPAMQHH 409
            |.::..|  :.||..:::      .:|:.|.:|...|...|       .:|....||
  Fly  1526 GLSLKRH--IDDVAVDDD------SLLEEDEDEMEMEMEMDMLEEEDEEEEELGDHH 1574

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42726	NP_732017.3	C2H2 Zn finger	74..94	CDD:275368	4/25 (16%)
		C2H2 Zn finger	103..123	CDD:275368	6/19 (32%)
		COG5048	<112..288	CDD:227381	40/176 (23%)
		C2H2 Zn finger	131..151	CDD:275368	3/19 (16%)
		Chordopox_A33R	151..>254	CDD:283591	31/103 (30%)
		C2H2 Zn finger	158..178	CDD:275368	6/19 (32%)
		C2H2 Zn finger	187..207	CDD:275368	9/19 (47%)
		C2H2 Zn finger	216..236	CDD:275368	8/19 (42%)
		C2H2 Zn finger	244..264	CDD:275368	3/19 (16%)
		C2H2 Zn finger	272..290	CDD:275368	0/17 (0%)
zld	NP_001285466.1	zf-C2H2_jaz	552..577	CDD:288983
		LIM	1328..1389	CDD:259829	21/87 (24%)
		C2H2 Zn finger	1328..1349	CDD:275368	9/47 (19%)
		C2H2 Zn finger	1357..1377	CDD:275368	6/19 (32%)
		C2H2 Zn finger	1386..1407	CDD:275368	9/20 (45%)
		zf-H2C2_2	1398..1422	CDD:290200	7/23 (30%)
		zf-C2H2	1413..1435	CDD:278523	10/21 (48%)
		C2H2 Zn finger	1415..1435	CDD:275368	8/19 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457219
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930