DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42726 and Zscan26

DIOPT Version :9

Sequence 1:	NP_732017.3	Gene:	CG42726 / 318709	FlyBaseID:	FBgn0261679	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	XP_017456272.1	Gene:	Zscan26 / 266792	RGDID:	727885	Length:	465	Species:	Rattus norvegicus

Alignment Length:	299	Identity:	81/299 - (27%)
Similarity:	124/299 - (41%)	Gaps:	45/299 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 DSCGHTKCRLCLVADV----------------------SDCLEC--RVARSVDIQETQETQARTS 60
            ||||..:.. |.:::.                      |.|||.  |:.::..:.|...|.....
  Rat   182 DSCGRVESS-CTMSEPIEAQCEDLSLKKYPAMPKGKTNSQCLETKERLVQNSGLIERDRTHTGER 245

  Fly    61 ADKRIIVTDKGYHCTVCNKDFRSRTQQYYHLTCGNDLLKKFNCKECGRRFATSSHLKYHLMSHEK 125
            :.:.::     |..:|..:          |.....:  |...|:|||:.|..||||..|...|..
  Rat   246 SCESVV-----YQSSVATE----------HQEISKE--KGHPCQECGKVFQRSSHLIRHQKIHLG 293

  Fly   126 QSKHSCSVCHKSFKQPIVLQRHMLTHNQEK-HLCPICQKVFRRKSSLASHLAIHSDLGLQFKCEL 189
            :..:.|..|.|.|.|...|..|:..|..|| :||..|.|.|||.|.|..|..|||. ....:|:.
  Rat   294 EKPYQCKECGKVFSQNAGLLEHLRIHTGEKPYLCIHCGKNFRRSSHLNRHQKIHSQ-DEPRECKE 357

  Fly   190 CSKHFQNKANLNQHLRKHDKNNIRHMCKVCQKSFLRQTTLRLHMKRHSNRERQSCSLCGKSYNDP 254
            |.|.|.....|..|.|.|.::. ||.|..|.|:|...:.|..|.:.|:..:...|::|.|::...
  Rat   358 CGKTFSRALLLTHHQRVHGRSK-RHHCNECGKAFSLTSDLIRHHRIHTGEKPFKCNVCQKAFRLN 421

  Fly   255 DALGRHLRQHKTAERYRCIQCDITINRKDNMLRHLRSMH 293
            ..|.:|:|.|...:.|:|.:|:....:|..:.:|.|..|
  Rat   422 SHLDQHVRIHNEEKLYKCSECNEAFRQKSGLFQHQRHHH 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42726	NP_732017.3	C2H2 Zn finger	74..94	CDD:275368	2/19 (11%)
		C2H2 Zn finger	103..123	CDD:275368	10/19 (53%)
		COG5048	<112..288	CDD:227381	57/176 (32%)
		C2H2 Zn finger	131..151	CDD:275368	7/19 (37%)
		Chordopox_A33R	151..>254	CDD:283591	36/103 (35%)
		C2H2 Zn finger	158..178	CDD:275368	9/19 (47%)
		C2H2 Zn finger	187..207	CDD:275368	7/19 (37%)
		C2H2 Zn finger	216..236	CDD:275368	6/19 (32%)
		C2H2 Zn finger	244..264	CDD:275368	6/19 (32%)
		C2H2 Zn finger	272..290	CDD:275368	4/17 (24%)
Zscan26	XP_017456272.1	SCAN	43..148	CDD:413396
		COG5048	<194..422	CDD:227381	65/246 (26%)
		C2H2 Zn finger	247..263	CDD:275368	3/30 (10%)
		C2H2 Zn finger	271..291	CDD:275368	10/19 (53%)
		C2H2 Zn finger	299..319	CDD:275368	7/19 (37%)
		C2H2 Zn finger	327..347	CDD:275368	9/19 (47%)
		C2H2 Zn finger	355..375	CDD:275368	7/19 (37%)
		C2H2 Zn finger	383..403	CDD:275368	6/19 (32%)
		C2H2 Zn finger	411..431	CDD:275368	6/19 (32%)
		C2H2 Zn finger	439..459	CDD:275368	5/19 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23226
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100