DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42726 and Zscan12

DIOPT Version :9

Sequence 1:	NP_732017.3	Gene:	CG42726 / 318709	FlyBaseID:	FBgn0261679	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	XP_038952124.1	Gene:	Zscan12 / 266716	RGDID:	628738	Length:	503	Species:	Rattus norvegicus

Alignment Length:	262	Identity:	71/262 - (27%)
Similarity:	115/262 - (43%)	Gaps:	29/262 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 VTDSCGHTKCR-LCLVADVSDCLECRVARSVDIQETQETQARTSADKRIIVTDKGYHCTVCNKDF 81
            :|::..|.:.: :|....|..|.||        .:|....:|....:||...|:.|.|..|.|.|
  Rat   252 LTENSNHAELQNICPGRKVHGCDEC--------GKTFSQHSRLIEHRRIHTGDRPYRCEECGKTF 308

  Fly    82 RSRTQQYYH--LTCGNDLLKKFNCKECGRRFATSSHLKYHLMSHEKQSKHSCSVCHKSFKQPIVL 144
            |.||....|  :..|.   |.:.|.||||.|...|.|..|...|..:..:.|:.|.|:|.|...|
  Rat   309 RWRTVLIRHKVVHTGE---KPYKCNECGRAFGQWSALNQHQRLHSGEKHYHCNECGKAFCQKAGL 370

  Fly   145 QRHMLTHNQEK-HLCPICQKVFRRKSSLASHLAIHSDLGLQ-FKCELCSKHFQNKANLNQHLRKH 207
            ..|:.:|.:.: :.|..|.|.|.|:|:|:.|..:|:  |.: ::|..|.:.|...::|..|...|
  Rat   371 FHHLKSHRRNRPYQCLQCNKSFNRRSTLSQHQGVHT--GTKPYECSDCGRAFVYNSSLATHQETH 433

  Fly   208 DKNNIRHMCKVCQKSFLRQTTLRLHMKRHSNRERQSCSLCGKSYNDPDALGRHLRQHKTAERYRC 272
            .|..:           ..|:......|.|::.:...||:|||::....:|..|.:.|.....|:|
  Rat   434 HKEKL-----------FTQSGPSQQRKNHTSEKSYKCSICGKTFVQKTSLIEHEQIHTEERPYKC 487

  Fly   273 IQ 274
            .:
  Rat   488 AE 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42726	NP_732017.3	C2H2 Zn finger	74..94	CDD:275368	8/21 (38%)
		C2H2 Zn finger	103..123	CDD:275368	9/19 (47%)
		COG5048	<112..288	CDD:227381	42/165 (25%)
		C2H2 Zn finger	131..151	CDD:275368	7/19 (37%)
		Chordopox_A33R	151..>254	CDD:283591	26/104 (25%)
		C2H2 Zn finger	158..178	CDD:275368	8/19 (42%)
		C2H2 Zn finger	187..207	CDD:275368	5/19 (26%)
		C2H2 Zn finger	216..236	CDD:275368	2/19 (11%)
		C2H2 Zn finger	244..264	CDD:275368	7/19 (37%)
		C2H2 Zn finger	272..290	CDD:275368	1/3 (33%)
Zscan12	XP_038952124.1	SCAN	43..155	CDD:128708
		COG5048	<209..429	CDD:227381	55/189 (29%)
		C2H2 Zn finger	273..293	CDD:275368	6/27 (22%)
		C2H2 Zn finger	301..321	CDD:275368	8/19 (42%)
		C2H2 Zn finger	329..349	CDD:275368	9/19 (47%)
		C2H2 Zn finger	357..377	CDD:275368	7/19 (37%)
		C2H2 Zn finger	385..405	CDD:275368	8/19 (42%)
		C2H2 Zn finger	413..451	CDD:275368	9/48 (19%)
		zf-C2H2	457..479	CDD:395048	7/21 (33%)
		C2H2 Zn finger	459..479	CDD:275368	7/19 (37%)
		C2H2 Zn finger	487..503	CDD:275368	1/3 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23226
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100