DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42726 and Zscan21

DIOPT Version :9

Sequence 1:	NP_732017.3	Gene:	CG42726 / 318709	FlyBaseID:	FBgn0261679	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	NP_001038168.1	Gene:	Zscan21 / 22697	MGIID:	99182	Length:	555	Species:	Mus musculus

Alignment Length:	197	Identity:	61/197 - (30%)
Similarity:	94/197 - (47%)	Gaps:	3/197 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 KKFNCKECGRRFATSSHLKYHLMSHEKQSKHSCSVCHKSFKQPIVLQRHMLTHNQEKHLCPICQK 163
            |::.|.|||:.|:.||:|..|..:|..:..:.|:.|.|:|.....|..|..||..::.....|.|
Mouse   357 KRYICAECGKAFSNSSNLTKHRRTHTGEKPYVCTKCGKAFSHSSNLTLHYRTHLVDRPYDCKCGK 421

  Fly   164 VFRRKSSLASHLAIHSDLGLQFKCELCSKHFQNKANLNQHLRKHDKNNIRHMCKVCQKSFLRQTT 228
            .|.:.|.|..|..:|:: ...::|:.|.|.|..|.:|.:|.|.|.... .:.|..|.|||.:...
Mouse   422 AFGQSSDLLKHQRMHTE-EAPYQCKDCGKAFSGKGSLIRHYRIHTGEK-PYQCNECGKSFSQHAG 484

  Fly   229 LRLHMKRHSNRERQSCSLCGKSYNDPDALGRHLRQHKTAERYRCIQCDITINRKDNMLRHLRSMH 293
            |..|.:.|:..:...|..|||::|......:|.|.|...:.|.|..|..|...|.|:.:|.| :|
Mouse   485 LSSHQRLHTGEKPYKCKECGKAFNHSSNFNKHHRIHTGEKPYWCSHCGKTFCSKSNLSKHQR-VH 548

  Fly   294 PG 295
            .|
Mouse   549 TG 550

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42726	NP_732017.3	C2H2 Zn finger	74..94	CDD:275368
		C2H2 Zn finger	103..123	CDD:275368	9/19 (47%)
		COG5048	<112..288	CDD:227381	51/175 (29%)
		C2H2 Zn finger	131..151	CDD:275368	6/19 (32%)
		Chordopox_A33R	151..>254	CDD:283591	30/102 (29%)
		C2H2 Zn finger	158..178	CDD:275368	6/19 (32%)
		C2H2 Zn finger	187..207	CDD:275368	8/19 (42%)
		C2H2 Zn finger	216..236	CDD:275368	7/19 (37%)
		C2H2 Zn finger	244..264	CDD:275368	7/19 (37%)
		C2H2 Zn finger	272..290	CDD:275368	6/17 (35%)
Zscan21	NP_001038168.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..74
		3 X 39 AA approximate tandem repeats	18..134
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	102..133
		SCAN	118..230	CDD:128708
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	204..243
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	263..354
		COG5048	<339..535	CDD:227381	54/179 (30%)
		C2H2 Zn finger	361..381	CDD:275368	9/19 (47%)
		C2H2 Zn finger	389..409	CDD:275368	6/19 (32%)
		C2H2 Zn finger	419..436	CDD:275368	6/16 (38%)
		C2H2 Zn finger	444..464	CDD:275368	8/19 (42%)
		C2H2 Zn finger	472..492	CDD:275368	7/19 (37%)
		C2H2 Zn finger	500..520	CDD:275368	7/19 (37%)
		C2H2 Zn finger	528..548	CDD:275368	7/20 (35%)
		zf-C2H2	528..548	CDD:333835	7/20 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23226
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100