DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42726 and Zfp13

DIOPT Version :9

Sequence 1:	NP_732017.3	Gene:	CG42726 / 318709	FlyBaseID:	FBgn0261679	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	XP_011244722.1	Gene:	Zfp13 / 22654	MGIID:	99159	Length:	546	Species:	Mus musculus

Alignment Length:	263	Identity:	78/263 - (29%)
Similarity:	114/263 - (43%)	Gaps:	36/263 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 KGYHCTVCNKDF----------RSRTQQYYHLTCGNDLLKKFNCKECGRRFATSSHLKYHLMSHE 124
            |.|.|..|.|.|          |:.|.:           |.:.|.:||:||..||||..|.:.|.
Mouse   298 KTYKCEQCGKGFSWHSHLVTHRRTHTGE-----------KPYTCTDCGKRFGRSSHLIQHQIIHT 351

  Fly   125 KQSKHSCSVCHKSFKQPIVLQRHMLTHNQEK-HLCPICQKVFRRKSSLASHLAIHSDLGLQFKCE 188
            .:..::|..|.|||.....|.:|...|..|| ::|..|.|.|.|:|.|.:|...|:. ....||.
Mouse   352 GEKPYTCPSCWKSFSHHSTLIQHQRIHTGEKPYVCDRCAKRFTRRSDLVTHQGTHTG-AKPHKCP 415

  Fly   189 LCSKHFQNKANLNQHLRKHDKNNIR-HMCKVCQKSFLRQTTLRLHMKRHSNRERQSCSLCGKSYN 252
            :|||.|...:.|..|.|.|  ..:: :.|..|.|.|.:::.|..|.:.|:..:...|..||||::
Mouse   416 ICSKCFTQSSALVTHQRTH--TGVKPYPCPECGKCFSQRSNLIAHNRTHTGEKPYHCLDCGKSFS 478

  Fly   253 DPDALGRHLRQHKTAERYRCIQCDITINRKDNMLRH----------LRSMHPGCAFASTVEMVTP 307
            ....|..|.|.|:....|.|..|..:.:|:.|:.||          |..:..|.|.|..:....|
Mouse   479 HSSHLTAHQRTHRGVRPYSCPLCGKSFSRRSNLHRHEKIHTTGPKALAMLMLGAAAAGALTAPPP 543

  Fly   308 RSS 310
            .|:
Mouse   544 AST 546

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42726	NP_732017.3	C2H2 Zn finger	74..94	CDD:275368	6/29 (21%)
		C2H2 Zn finger	103..123	CDD:275368	10/19 (53%)
		COG5048	<112..288	CDD:227381	56/177 (32%)
		C2H2 Zn finger	131..151	CDD:275368	7/19 (37%)
		Chordopox_A33R	151..>254	CDD:283591	34/104 (33%)
		C2H2 Zn finger	158..178	CDD:275368	8/19 (42%)
		C2H2 Zn finger	187..207	CDD:275368	8/19 (42%)
		C2H2 Zn finger	216..236	CDD:275368	6/19 (32%)
		C2H2 Zn finger	244..264	CDD:275368	8/19 (42%)
		C2H2 Zn finger	272..290	CDD:275368	6/27 (22%)
Zfp13	XP_011244722.1	KRAB	124..179	CDD:214630
		C2H2 Zn finger	302..322	CDD:275368	5/19 (26%)
		zf-H2C2_2	314..339	CDD:372612	8/35 (23%)
		C2H2 Zn finger	330..350	CDD:275368	10/19 (53%)
		zf-H2C2_2	342..367	CDD:372612	9/24 (38%)
		C2H2 Zn finger	358..378	CDD:275368	7/19 (37%)
		COG5048	<360..520	CDD:227381	51/162 (31%)
		C2H2 Zn finger	386..406	CDD:275368	8/19 (42%)
		C2H2 Zn finger	414..434	CDD:275368	8/19 (42%)
		C2H2 Zn finger	442..462	CDD:275368	6/19 (32%)
		C2H2 Zn finger	470..490	CDD:275368	8/19 (42%)
		C2H2 Zn finger	498..518	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23226
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100