DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31380 and CG6830

DIOPT Version :9

Sequence 1:	NP_733121.1	Gene:	CG31380 / 318701	FlyBaseID:	FBgn0051380	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster

Alignment Length:	446	Identity:	111/446 - (24%)
Similarity:	186/446 - (41%)	Gaps:	90/446 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 WLT----AEYLEAALRRYYQNNELRVESMVINPALGKGENYGAILTRIHLVYSSIVEEHLIAKTV 64
            ||.    .|.|.|.:.::     .::....:.||:..||||..::.||.:              .
  Fly    49 WLNQTQFEELLAADVDQF-----SKIVGFRVKPAMAPGENYATLMLRISI--------------D 94

  Fly    65 LEYEDAETK----MKKAPYD------------IYNRELEIYEQVLPKLQEL-----AGEQLCPKI 108
            :|..|..||    |.|.|:|            .:..|...|.::|||::||     ...:..|:.
  Fly    95 VELTDKSTKLVSFMMKVPHDTPQMEQMMSMANFFTSENAAYTEILPKMEELYKAKGLDIKFAPRA 159

  Fly   109 LHIDRQR-----GALIMEDLSYKGFVMAPRLQRLDEQHVSLVLRKLAKMQAASA----------- 157
            ..:|..:     ..::|.||...||....||:.|:.:.....|.:||:..||.|
  Fly   160 FKLDATKEPKVANTVLMHDLGQNGFKNINRLECLNLEQTKFALTRLAQFHAAGATMVQVHGPYPD 224

  Fly   158 VLENNLLENNFSLTEYDKGFFNRYTESFSAYFLGCLKS-----CANYLKTQAGYEHHAKL---LD 214
            :..|.::.||              .|:..|:..|.|.|     .||..|.:.|.|:..||   |.
  Fly   225 IFVNGVMGNN--------------KEAIIAFMEGMLASFRTSFMANLDKFKNGEEYREKLEKALA 275

  Fly   215 ELAPYYMGLGLRCFKQEQTHINVLTHGDLWTNNMMFKY-EAGVPSDVLLIDFQYAFWGSPTLD-I 277
            .|...:|.||:    .:....|.|.|||.|.||::||. .:|...|::.:|||...:|||.:| :
  Fly   276 GLTMEFMKLGI----VDPNEFNALNHGDCWMNNLLFKMNSSGDLEDMVFVDFQNPKYGSPAMDLL 336

  Fly   278 HHLLNTSAVEQVRSELQMKMRGVYHDVFVGELQRLGFKGQRLPSRKQFHLESEQKRFYAVHCGLL 342
            :.::::..::...|.....:|. |.:..|..|..|||.| |.||.::.|....:...:.:...:.
  Fly   337 YFIISSVQIDYKLSHFDFFIRH-YQEALVKHLGILGFTG-RKPSLRELHRTLIKYGGWVLFPTIS 399

  Fly   343 LLPVLLNTDETDADFAALLSDQPRGMDMKRRLYLNPGIQDSIKQMVKHFELEGLLD 398
            :||::|......|.|...:||...|:..:..||.|...|:.|::::...:..|.|:
  Fly   400 VLPLVLLDPTQSATFDNFMSDSADGVSFRGSLYANKRCQEYIERILPWLDNRGFLE 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31380	NP_733121.1	EcKinase	36..314	CDD:281023	82/324 (25%)
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023	82/324 (25%)
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459436
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850