DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31321 and Slc46a2

DIOPT Version :9

Sequence 1:	NP_731899.1	Gene:	CG31321 / 318681	FlyBaseID:	FBgn0051321	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_001100122.1	Gene:	Slc46a2 / 298034	RGDID:	1310485	Length:	480	Species:	Rattus norvegicus

Alignment Length:	432	Identity:	89/432 - (20%)
Similarity:	173/432 - (40%)	Gaps:	65/432 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   141 MAAIFPLIVLLFAGGWADRYNKRKPCMIMPIIGEALSFTCQIISSIFFESLPMEFGAYCEAIVPA 205
            :..:.||:.....|..:|||: ||..:...::|..||....::..:....|.:.:||   |.:..
  Rat    86 VVGLTPLLSAYVLGWLSDRYH-RKISICTAMLGFLLSRIGLLLKVMLDWPLEVMYGA---AALNG 146

  Fly   206 LFGGLTFCLMAIYSYITIATPEEDRVFRFGIFAMFVTGVPFIGQPISGVLFTTL-GYTWS----F 265
            |.||.:.....:.:..:::..:..|..|..:..:.:....|.|...||.||..: |::..    .
  Rat   147 LCGGFSAYWSGVMALGSLSCSQSRRSVRLILIDLVLGLAGFCGSMASGHLFKQIVGHSAQGLLLT 211

  Fly   266 ASAIVFQLIAIFYIIFFIKEVKTTPTTSTTANEPPPLPTSLPPKQQGADNM--AYETTNLDELQG 328
            |.::.....|:||.:|.:|           ..|....|..:.|.......|  .|.|.:.|:
  Rat   212 ACSVGCAAFALFYSLFVLK-----------VPEAVSKPNKVHPTVDTVSGMMGTYRTLDPDQ--- 262

  Fly   329 NKNVNFQLTPQMEPKVEVVPPKRSLLKELFDPTLVLDCIRFPLVKRPNNGRMLLILL-LCAYFLT 392
                      |.:|.::..||.                   |..::|:...:.|:.: ...|.|.
  Rat   263 ----------QDKPNIQANPPT-------------------PGKEKPSQAIIALLFVGAIVYDLA 298

  Fly   393 VGPTSGENDYWYRFTLK-KLAWNGNDFSIYLTLSSGAAL-VGTFIGTAILSKLLKVSDSMIGMLS 455
            |   .|..|....|.|| .|.|  |...:...::||..: :.:|:|..:.|:..:  |:.:.::.
  Rat   299 V---VGTLDVMALFVLKDPLHW--NQVQLGYGMASGYIIFITSFLGVLVFSRYFR--DTTMIIIG 356

  Fly   456 ALSIVCSRVLFAFSSSTASFYVAGVVDMFVSLRVIAIKTIGSSIVAGDELSKMYSIFGISEPIAQ 520
            .:|.....:|.||...|..||:|..|.:|..:.:..|::..|.:|......|::.|..:...:..
  Rat   357 MVSFGSGALLLAFVKKTYMFYIARAVMLFALIPITTIRSAMSKLVKDSSYGKIFVILQLCLALTG 421

  Fly   521 FIFPPIFSEIYKSTVDSFPGAIWLFGE-IFYIPNVLVFVVCY 561
            .:...::::||:.|::.|.|..:|... :.::..|.:.||.|
  Rat   422 VVTSTMYNKIYQLTLNKFAGTCFLLSSFLSFLAIVPIGVVAY 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31321	NP_731899.1	MFS	141..>271	CDD:119392	28/134 (21%)
		MFS_1	143..>271	CDD:284993	28/132 (21%)
		MFS	<379..559	CDD:119392	40/183 (22%)
Slc46a2	NP_001100122.1	MFS	86..433	CDD:119392	80/400 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347638
Domainoid	1	1.000	71	1.000	Domainoid score	I9200
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23507
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.850