Protein Alignment CG31321 and SLC46A3

DIOPT Version :9

• Sequence 1: NP_731899.1
• Gene: CG31321 / 318681
• FlyBaseID: FBgn0051321
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_001129391.1
• Gene: SLC46A3 / 283537
• HGNCID: 27501
• Length: 463
• Species: Homo sapiens
• Alignment Length: 476
• Identity: 101/476 - (21%)
• Similarity: 185/476 - (38%)
• Gaps: 121/476 - (25%)

  Fly   130 LAADVSGKRAPMAAIFPLIVLLFAGGWADRYNKRKPCMIMPIIGEALSFTCQIISSIFFESLPME 194
            |..|:||....:.:.|.|:.:      :|.|.::.| ||:..:| ||:.:..:....:| :.|.:
Human    74 LQMDISGLIPGLVSTFILLSI------SDHYGRKFP-MILSSVG-ALATSVWLCLLCYF-AFPFQ 129

  Fly   195 -------FGAYCEAIVPALFGGLTFCLMAIYSYITIATPE-EDRVFRFGIFAM---FVTGVPFIG 248
                   .||:|        |..|....|.::||.....| :.:..|..|...   .|||:..:.
Human   130 LLIASTFIGAFC--------GNYTTFWGACFAYIVDQCKEHKQKTIRIAIIDFLLGLVTGLTGLS 186

  Fly   249 QPISGVLFTTLGYTWSFASAIVFQLIAIFYIIFF----IKEVKTTPTTSTTANEPPPLPTSLPPK 309
               ||.....||:.|||....|...:.:.||:||    :||..:...|.:.:
Human   187 ---SGYFIRELGFEWSFLIIAVSLAVNLIYILFFLGDPVKECSSQNVTMSCS------------- 235

  Fly   310 QQGADNMAYETTNLDELQGNKNVNFQLTPQMEPKVEVVPPKRSLLKELFDPTLVLDCIRFPLVKR 374
             :|..|:.|.|..|.:....|                   :|.||           |
Human   236 -EGFKNLFYRTYMLFKNASGK-------------------RRFLL-----------C-------- 261

  Fly   375 PNNGRMLLILLLCAYFLTVG--PTSGENDYWYRFTL----KKLAWNGNDFSIYLTLSSGAALVGT 433
                 :||..::..:|:.:|  |.         |.|    ..|.|| ..|..|.:....|:.:.:
Human   262 -----LLLFTVITYFFVVIGIAPI---------FILYELDSPLCWN-EVFIGYGSALGSASFLTS 311

  Fly   434 FIGTAILSKLLK-VSDSMIGMLSALSIVCSRVLFAFSSSTASFYVAGVVDMFVSLRVIAIKTIGS 497
            |:|..:.|..:: :..:.||:.:.::   ...:.||:|:|...::|.|..:|..:....::::.|
Human   312 FLGIWLFSYCMEDIHMAFIGIFTTMT---GMAMTAFASTTLMMFLARVPFLFTIVPFSVLRSMLS 373

  Fly   498 SIVAGDELSKMYSIFGISEPIAQFIFPPIFSEIYKSTVDSFPGAIWLFGE-IFYIPNVLVFVV-C 560
            .:|...|...:::.....|.:........|:.||.:||..:||..:|... :..:|.:.:.|| |
Human   374 KVVRSTEQGTLFACIAFLETLGGVTAVSTFNGIYSATVAWYPGFTFLLSAGLLLLPAISLCVVKC 438

  Fly   561 -------YFLLRRRKANEEKS 574
                   |.||.:.:::|:.|
Human   439 TSWNEGSYELLIQEESSEDAS 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31321	NP_731899.1	MFS	141..>271	CDD:119392	33/140 (24%)
		MFS_1	143..>271	CDD:284993	33/138 (24%)
		MFS	<379..559	CDD:119392	38/187 (20%)
SLC46A3	NP_001129391.1	MFS_1	81..399	CDD:311564	80/407 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23507
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920