Protein Alignment Dnaaf5 and Dnaaf5

DIOPT Version :10

• Sequence 1: NP_731905.1
• Gene: Dnaaf5 / 318680
• FlyBaseID: FBgn0288976
• Length: 845
• Species: Drosophila melanogaster
• Sequence 2: NP_001128329.1
• Gene: Dnaaf5 / 304332
• RGDID: 1566028
• Length: 851
• Species: Rattus norvegicus
• Alignment Length: 865
• Identity: 220/865 - (25%)
• Similarity: 367/865 - (42%)
• Gaps: 160/865 - (18%)

  Fly     9 KICSDLESSDRRLKTTVLDELLDKCKEAT--NSESADKIADVFDKLYL-HLLKCYEDRFESVRSK 70
            ::...||:..:..:...|:.|....:||.  .::|| .....:.:|.| .||:...|..|..|:.
  Rat    28 RLLPGLETESKLGRRRALEALEHALEEAVRPGTDSA-AFQGPWARLLLPRLLRLLTDPAEGCRAL 91

  Fly    71 AIQVVSAFL-SSLPPTDFHLMNVVSTLAERMGKAETV----EPSEEIRLLYIAQLNLMI-----C 125
            |..::...| .:..|.| .|..::..|..|:.:.|:.    ||.||:||..:..|:|.:     .
  Rat    92 AAHLLDLGLRRAARPRD-ALPRLLPALTARLARPESTRPPPEPCEELRLALVQLLHLAVDLGGAA 155

  Fly   126 LYEKMENVGVFRECYPLVVKILIKSIKDDYPVVQREGCSAVVTLSRLADTQEFRPFTESILLPLY 190
            |...:::          .|:.|..::.|.:..|:||||.....|:| |..:.|...:||::.||.
  Rat   156 LAPHLDD----------AVRALRGALLDPFAAVRREGCECAAALAR-AIPEHFHMQSESLIGPLM 209

  Fly   191 TMLNHKHAQARISAIQAIARLSLHMDASGDAMRRLFNEVSPLLMDTMPLVRREVGQMGILMLMEL 255
            ..::|:|.:.|::.|:|..  ::....:|:::..:.:..:..|.|.:|.||:.|..:....|:.|
  Rat   210 QTISHQHWKVRVAVIEATG--TVIQFGNGNSVDDVLSHFAQRLFDDVPQVRQAVTSVVGGWLLNL 272

  Fly   256 LDRYSFFERILPLVLCCLKDESPEVLNHIYPQWLKCGIQYFNENEAELSQQ-EISDLPVENYPKD 319
            .||||||.::.||:|....||.|||.......|.|.|:|:..||||:|..: :.:..|..|||:.
  Rat   273 RDRYSFFHKLTPLLLSSFSDEMPEVRQTATSLWEKVGLQWQEENEADLKDKLDFASPPPPNYPEH 337

  Fly   320 VKRPTIGCRGLVQRSL-RLLQLITRETSDWKDNVRLHALKLLYQFVLHAEAAMTAKFFEIYGDLA 383
            ..||.:|||.||.|:| ::|..|..:.:||....||.|.:||...:||||..:|.....:...|.
  Rat   338 ESRPGLGCRELVFRNLSKVLPAICHDITDWVVGTRLKAAQLLPVLLLHAEDHITQHLEIVLRTLH 402

  Fly   384 HACIDHVAEVNAEAAKVADLMGRLLSYDAWID-------------------HGFDGLERNARESY 429
            .||.|....|.:...:.|:|:|..:|.:.::.                   ....|..|||.:.:
  Rat   403 QACTDEEKAVVSSCVRAAELIGTFVSPEVFLKLILAMLKKAPSASGLLILASVIRGCPRNALQPH 467

  Fly   430 MRCF------YHMFTASLGGTYEQLMRLAKLLRCTDYSHTLKPGFQH-------YILKLLNTIV- 480
            ::..      .|:...|...:|     |..||.|.   .||....|.       .:.::|.||:
  Rat   468 LKVIATELAQEHICQGSENNSY-----LEHLLLCV---QTLLSVCQEDCCAASLQLSEVLVTIMA 524

  Fly   481 -----------DKTLKINAGQNEL---EDLYESVYVCAIKVMALSSSLENV----GDEDVNFGQT 527
                       .||:...|...::   :|||..         .|.:.||.:    |:..|:..|.
  Rat   525 VSDAVSLEKKAQKTMDTLAEVEDIPSSQDLYRK---------HLGALLERLTASHGEWTVHSVQL 580

  Fly   528 LIEKMVKLLNTSVPKIHERWFHLALQDVI-NLDAALEDNAEPVMLLNGLINMCHIRATYVHDLIE 591
            |  |...||..:.|.:.|     |||.|| .|.|.|:...:|           |:|
  Rat   581 L--KFTVLLTQAGPAVGE-----ALQHVIPTLRACLQPTTDP-----------HMR--------- 618

  Fly   592 KVKIVFQHCCDSAQVKIFSSLSLATLFWSKTMNVERESSTQM---LSEFVSQIVEPYLTWKAGSN 653
                          :|:||.||...|....|:    :|..|.   |...::.|:.|.|.|.||..
  Rat   619 --------------LKLFSILSSLLLRPKDTV----DSQGQFHGYLDMVINDILAPNLQWHAGRT 665

  Fly   654 AEAMRSLAMATLCALAQGAESESVEVLPSLAKYMPSL---LEDRNVTTRHYAIKAVVYFREMSVE 715
            |.|:|:..::.|.||.......:.:|..:....||.:   |||.:.|||..:.:.:..|.:.|.:
  Rat   666 AAAIRTATISCLWALISSDILSAKQVQEAQETLMPQVLATLEDDSQTTRLISCRIISRFLKNSGD 730

  Fly   716 DLKPLAY-----ATMQRMDDPSAGIRILAALAMGKLKPKFAETDTEENYEKEVWDAIVKRAMDLL 775
            .::|..:     ..::|:||.|..:|:.||.|:..........|.:..|:..|  ..:.|.   |
  Rat   731 TMEPEKFLKVYPELLKRLDDVSNDVRMAAASALLTWLKCIESVDGKSAYQSSV--QFLYRE---L 790

  Fly   776 LLYHESPEKDMRAAVAVTLK 795
            |::.:.||..::..|...||
  Rat   791 LVHLDDPESAIQDTVLEVLK 810

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dnaaf5	NP_731905.1	HEAT repeat	52..80	CDD:293787	9/29 (31%)
		HEAT repeat	91..124	CDD:293787	11/36 (31%)
		HEAT	141..280	CDD:441023	42/138 (30%)
		HEAT repeat	143..174	CDD:293787	10/30 (33%)
		HEAT repeat	184..214	CDD:293787	8/29 (28%)
		HEAT repeat	224..254	CDD:293787	7/29 (24%)
Dnaaf5	NP_001128329.1	SPS1	<19..192	CDD:440281	42/176 (24%)
		HEAT	161..309	CDD:441023	45/147 (31%)
		HEAT repeat	163..191	CDD:293787	9/27 (33%)
		HEAT repeat	203..232	CDD:293787	8/28 (29%)
		HEAT repeat	241..268	CDD:293787	6/26 (23%)
		HEAT repeat	355..381	CDD:293787	9/25 (36%)
		HEAT repeat	394..419	CDD:293787	5/24 (21%)
		SCC2	<663..>811	CDD:472763	40/155 (26%)
		HEAT repeat	698..726	CDD:293787	9/30 (30%)
		HEAT repeat	736..773	CDD:293787	9/41 (22%)
		HEAT repeat	782..811	CDD:293787	7/28 (25%)