Protein Alignment Dnaaf5 and Dnaaf5

DIOPT Version :10

• Sequence 1: NP_731905.1
• Gene: Dnaaf5 / 318680
• FlyBaseID: FBgn0288976
• Length: 845
• Species: Drosophila melanogaster
• Sequence 2: XP_061504205.1
• Gene: Dnaaf5 / 1281365
• VectorBaseID: AGAMI1_012771
• Length: 851
• Species: Anopheles gambiae
• Alignment Length: 818
• Identity: 282/818 - (34%)
• Similarity: 456/818 - (55%)
• Gaps: 54/818 - (6%)

  Fly    42 ADKIADVFDKLYLHLLKCYEDRFESVRSKAIQVVSAFLSSLPPTDFHLMNVVSTLAERMGKAETV 106
            |::...:||..|||:|:||.|||||||:.|:..:.|.|..|||.|::|..:|..||:|:|:|||:
Mosquito    44 AEECPRIFDDTYLHILRCYGDRFESVRTLAVAAMDALLGKLPPNDYYLGCIVPVLAKRIGQAETI 108

  Fly   107 EPSEEIRLLYIAQLNLMICLYEKMENVGVFRECYPL------VVKILIKSIKDDYPVVQREGCSA 165
            |.|||:||..:.||..::..|...:.   .|...||      |:..||||::|.:|..|::.|..
Mosquito   109 EDSEEVRLQLLEQLETLVAKYSDPDG---SRGGDPLLKVLDSVIDTLIKSLRDPFPAAQKKSCEI 170

  Fly   166 VVTLSRLADTQEFRPFTESILLPLYTMLNHKHAQARISAIQAIARLSLHMDASGDAMRRLFNEVS 230
            |:.|:....:..:|  .|:::.|..::|.|:|:..||:|::|:..||||:.::||.:..:...||
Mosquito   171 VIALAEATPSLHYR--AEALVAPAKSILTHRHSANRIAAVEALGVLSLHILSNGDCVSEIIMAVS 233

  Fly   231 PLLMDTMPLVRREVGQMGILMLMELLDRYSFFERILPLVLCCLKDESPEVLNHIYPQWLKCGIQY 295
            |||||.:|.|||..|::|.|||.:|.||||||.|||||||.||.||:.|:...|...|.:.|..|
Mosquito   234 PLLMDDVPFVRRACGRVGCLMLQKLRDRYSFFHRILPLVLNCLCDETVEMREDIEAGWKQAGELY 298

  Fly   296 FNENEAELSQQEISDLPVENYPKD-VKRPTIGCRGLVQRSLRLLQLITRETSDWKDNVRLHALKL 359
            :.|||.|||:..:.:...:.||.: .:|||:.||.:||||||::.|:..|..:||:|:||||.||
Mosquito   299 YRENETELSKAALIETVPKGYPGERYRRPTLACRAIVQRSLRVVNLVLHEMEEWKENIRLHATKL 363

  Fly   360 LYQFVLHAEAAMTAKFFEIYGDLAHACIDHVAEVNAEAAKVADLMGRLLSYDAWIDHGFDGLERN 424
            |.|.|||||.:.:..|.|:...||.||:|....:.:||..|.:|||.||.||.|..|.....:..
Mosquito   364 LKQIVLHAERSFSTLFLEVNPVLAKACMDAEKSIVSEALSVCELMGILLDYDTWSQHMLATFKNY 428

  Fly   425 ARESYMRCFYHMFTASLGGTY--EQLMRLAKLLRCTDYSHTLKPG-FQHYILKLLNTIVDKTLKI 486
            .....:||...:|.:.:....  :.:.:.|.||...|..|..:.. :|..:|:..:.:.....|.
Mosquito   429 PTIGQLRCMRTLFASCVQDEVKCKDVRKFATLLLDPDVCHNHRDAVYQRELLEFCSILASSGQKQ 493

  Fly   487 NAGQNELED----------------LYESVYVCAIKVMALSSSLE---NVGDEDVNFGQTLIEKM 532
            .|....||:                |..::|..|:||:|....||   :|.|    .|.|::
Mosquito   494 EALTARLEEITVCESNDSTAGEQQTLERTLYTVALKVVAFCYGLEDRASVRD----LGMTVL--- 551

  Fly   533 VKLLNTSVPKIHERWFHLA--LQDVINLDAALEDNAEPVMLLNGLINMCHIRATYVHDLIEKVKI 595
             .||:::|.::|:.  |||  |..:.:|::...|.:..::||.|::.:|..:.:|...|.|.::.
Mosquito   552 -GLLDSNVDRLHQH--HLASVLCKIEHLESENSDASTSILLLCGIVAVCGFQDSYFTILNETLQK 613

  Fly   596 VFQHCCDSAQVKIFSSLSLATLFWSKTMNVERESSTQMLSEFVSQIVEPYLTWKAGSNAEAMRSL 660
            ...|.....:||:||::|:|.|.|:......:|....||......::.|:|.|.||.:||::|::
Mosquito   614 AVAHAAPEGKVKLFSAISVAMLSWNVHNAQPKEDQIAMLRALTDAVIAPHLVWSAGRSAESVRAM 678

  Fly   661 AMATLCALAQGAE-SESVEVLPSLAKYMPSLLEDRNVTTRHYAIKAVVYFREMSVEDLKPLAYAT 724
            |.|...::|||.: :..:.:||:....:..|::|..:.||.|::||:|..:.::.|.||.:|:..
Mosquito   679 ATACFASMAQGVDPNVYMSLLPTYLNVLSGLIDDNCIATRAYSLKALVRLQALNFESLKLIAFPI 743

  Fly   725 MQRMDDPSAGIRILAALAMGKLKPKFAETDTEENYEKEVWDAIVKRAMDLLLLYHESPEKDMRAA 789
            |.|:||||..:|.|||:.:|:|:...|.::..:....:.|..|:::.:.::.|:.|.||..:|.|
Mosquito   744 MSRLDDPSGEVRELAAVCLGRLQLDVALSEDGQQNTIDRWQDILRQILSVMFLHLEHPETKLRCA 808

  Fly   790 VAVTLKVLAKSHPEAWE--ERYQRALP--MAQKKDLLT 823
            :..:||.|   |.:..|  ||....:|  .:.||||.|
Mosquito   809 IFDSLKRL---HTDNRELIERLASDVPSGCSYKKDLET 843

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dnaaf5	NP_731905.1	HEAT repeat	52..80	CDD:293787	15/27 (56%)
		HEAT repeat	91..124	CDD:293787	16/32 (50%)
		HEAT	141..280	CDD:441023	63/144 (44%)
		HEAT repeat	143..174	CDD:293787	11/30 (37%)
		HEAT repeat	184..214	CDD:293787	10/29 (34%)
		HEAT repeat	224..254	CDD:293787	16/29 (55%)
Dnaaf5	XP_061504205.1	None