Protein Alignment Dnaaf5 and dnaaf5

DIOPT Version :10

• Sequence 1: NP_731905.1
• Gene: Dnaaf5 / 318680
• FlyBaseID: FBgn0288976
• Length: 845
• Species: Drosophila melanogaster
• Sequence 2: NP_001429653.1
• Gene: dnaaf5 / 100535063
• ZFINID: ZDB-GENE-120511-3
• Length: 836
• Species: Danio rerio
• Alignment Length: 876
• Identity: 215/876 - (24%)
• Similarity: 398/876 - (45%)
• Gaps: 149/876 - (17%)

  Fly    15 ESSDRRLKTTVLDELLDKCKEATNSESADKIADVFDKLYLHLLKCYEDRFESVRSKAIQVVSAFL 79
            |:.::||.:..:.|||. |                  |...||||..|..|:.|..:||::..|:
Zfish    42 ETVEQRLSSGAMQELLG-C------------------LLKPLLKCLSDPAETCRDASIQIIVGFI 87

  Fly    80 SSLPPTDFHLMNVVSTLAERMGKAETVEPSEEIRLLYIAQLNLMICLYEKMENVGVFRECYPLVV 144
            .::|..:..|..::..||:|:|..|.:||:||:||..:..|:|::.:..|  .:..:.|.   ::
Zfish    88 RAVPKPEDCLPYLMPALAQRLGGKEILEPAEELRLALMEMLSLLVEVCGK--QIAPYLED---LI 147

  Fly   145 KILIKSIKDDYPVVQREGCSAVVTLSRLADTQEFRPFTESILLPLYTMLNHKHAQARISAIQAIA 209
            |||.::|.|.:..|::|.|...|::::.. .:.|....||:|.||...::|:|:|.|:||.|||.
Zfish   148 KILQRTISDPFAEVKKESCKCTVSVAQCI-PEHFHLQAESLLKPLLQTISHQHSQVRVSATQAIG 211

  Fly   210 RLSLHMDASGDAMRRLFNEVSPLLMDTMPLVRREVGQMGILMLMELLDRYSFFERILPLVLCCLK 274
            .:..:  ::|..:..:.:.::..|.|..|.||:.|..:....|:.|.||||:|.:::||:|..:.
Zfish   212 AVIQY--SAGKNVDEVLSHLAQRLFDDSPRVRKAVTLVVGDWLLRLPDRYSYFHKLIPLLLTSVS 274

  Fly   275 DESPEVLNHIYPQWLKCGIQYFNENEAELSQQEISDLPVEN-YPKDVKRPTIGCRGLVQRSL-RL 337
            ||.||:.:.....|.:.|.|:..|||.:|..:....||... |....:||.:|||.||.|:| :|
Zfish   275 DEIPEIRSLAENSWKQVGAQWEKENEDDLKDKMDFQLPAPALYTSGGERPGLGCRELVVRNLSKL 339

  Fly   338 LQLITRETSDWKDNVRLHALKLLYQFVLHAEAAMTAKFFEIYGDLAHACIDHVAEVNAEAAKVAD 402
            |..:.|:..||....|:..::||...:||||...|.....:...|.|||.|...:|..:..:.|.
Zfish   340 LPAMGRDIGDWLVQTRVKTVQLLRVLLLHAEDHCTQHLQMLLTVLYHACADAETDVRTQCLESAK 404

  Fly   403 LMGRLLSYDAWIDHGFDGLERNARESYMRCFYHMFTASLGGTYEQLMRLAKLLRCTDYSHTLKPG 467
            |:|..:|.:.::......:|.::            :.|....:..||.|..:|..:. ..||:|
Zfish   405 LLGVFVSPEVYLKLLLPHVEDSS------------SCSSASPWAPLMVLGAVLSGSS-RETLRP- 455

  Fly   468 FQHYILKLLNTIVDKTLKINAGQNELEDLY-ESVYVCAIKVMALSSSLENVGDEDVN-FGQTLIE 530
               :::|:.:|:....:.:.:.|    .|| :.:.||...|:       .||.:|.: ....|::
Zfish   456 ---HLVKIGDTLAQPEVCLGSQQ----VLYVDQLLVCVDAVL-------GVGQQDCDVISLQLLK 506

  Fly   531 KMVKLLNTSVPKIHERWFHLALQDVINLDAALEDNAEPVMLLNGLINMCHIRATYVHDL------ 589
            .:|.:  .||...||:  |...::::          ..|.....|..:|.:...::.||
Zfish   507 VLVSV--QSVASQHEQ--HSKAEELL----------RSVCAAQALSGVCDLYRQHMADLLQWLSD 557

  Fly   590 ---------IEKVKI--------------------VFQHCCDSA-----QVKIFSSLSLATLFWS 620
                     |:|.::                    :.:.|.|.:     ::.||:.||...|...
Zfish   558 SHQTWTSFSIQKTQLEIIAMQSGPVVGEFLPALLPLLKSCVDPSREPEMRLHIFTMLSKLLLDAK 622

  Fly   621 KTMNVERESSTQMLSEFVSQ-IVEPYLTWKAGSNAEAMRSLAMATLCALAQG----AESESVEVL 680
            .|::.:.:....|  |.|.| ::.|.|.|::|.:|.|:|:.|::.|.|:..|    || ..|..:
Zfish   623 NTLDSQGQFGEHM--EMVLQDLLMPNLVWRSGRSAAAVRTAALSCLLAVLHGEAFPAE-RVVSAV 684

  Fly   681 PSLAKYMPSLLEDRNVTTRHYAIKAV-----VYFREMSVEDLKPLAYATMQRMDDPSAGIRILAA 740
            .||:..:.|.||:.:...|..|.:::     :..:::|.:.|..:....::|:||.|..:|:.|.
Zfish   685 DSLSSLLISALEEDSKLARLLACRSLTSLLKITAQQISTDKLNQVYPELLKRVDDSSEDVRVEAL 749

  Fly   741 -------LAMGKLKPKFAETDTEENYEKEVWDAIVKRAMDLLLLYHESPEKDMRAAVAVTLKVLA 798
                   .::||            ||:.:.....::.....||||.:.|:..::..|...|||.:
Zfish   750 KSLSVWFCSLGK------------NYDMQSNRPHLELLFQQLLLYMDDPDTTVQNTVLGVLKVAS 802

  Fly   799 KSHPEAWEERYQRALPMAQKKDLLTELYDKL 829
            ....:..:::.:    ..::|....|..|||
Zfish   803 AVDGDLLQQQTE----SVREKQRSPEYCDKL 829

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dnaaf5	NP_731905.1	HEAT repeat	52..80	CDD:293787	11/27 (41%)
		HEAT repeat	91..124	CDD:293787	13/32 (41%)
		HEAT	141..280	CDD:441023	44/138 (32%)
		HEAT repeat	143..174	CDD:293787	9/30 (30%)
		HEAT repeat	184..214	CDD:293787	13/29 (45%)
		HEAT repeat	224..254	CDD:293787	7/29 (24%)
dnaaf5	NP_001429653.1	None