Protein Alignment Dnaaf5 and dnaaf5

DIOPT Version :10

• Sequence 1: NP_731905.1
• Gene: Dnaaf5 / 318680
• FlyBaseID: FBgn0288976
• Length: 845
• Species: Drosophila melanogaster
• Sequence 2: XP_002941855.2
• Gene: dnaaf5 / 100494246
• XenbaseID: XB-GENE-5902235
• Length: 839
• Species: Xenopus tropicalis
• Alignment Length: 801
• Identity: 204/801 - (25%)
• Similarity: 374/801 - (46%)
• Gaps: 87/801 - (10%)

  Fly    34 KEATNSE-SADKIADVFDKLYLHLLKCYEDRFESVRSKAIQVVSAFLSSLPPTDFHLMNVVSTLA 97
            |||.|.. |:..:.|||.:|...||:|..|..|..|..::|::...:|::|..:..|..::..|:
 Frog    41 KEAMNERLSSAVLQDVFLELLKPLLRCLSDPMEKCRELSVQIIVHCVSNVPRPEDSLPYLMPALS 105

  Fly    98 ERMGKAETVEPSEEIRLLYIAQLNLMICLYEKMENVGVFRECYPL---VVKILIKSIKDDYPVVQ 159
            :|:|:.|.||||||:||..:..|:|::      |..|  ::..|.   ::||..::|.|.:|.|:
 Frog   106 QRLGQQEVVEPSEELRLSMVELLSLVV------EVCG--KKLAPYLDEMIKIFQRTIVDPFPDVK 162

  Fly   160 REGCSAVVTLSRLADTQEFRPFTESILLPLYTMLNHKHAQARISAIQAIARLSLHMDASGDAMRR 224
            :|.|......::.. .:.|....||::.||...::|:|::.|::.||...  ::....||.::..
 Frog   163 KESCKCASNCAQCI-PEHFHMQAESLIKPLMQTISHQHSKVRVAVIQTTG--TVIQFGSGKSVDD 224

  Fly   225 LFNEVSPLLMDTMPLVRREVGQMGILMLMELLDRYSFFERILPLVLCCLKDESPEVLNHIYPQWL 289
            :.:.::..|.|....||:.|..:....|::|.|||||:.:::||:|....||.||:.......|.
 Frog   225 VMSHLAQRLFDDSIQVRQAVTVVVGDWLLQLRDRYSFYHKLIPLLLSSTTDEIPEIRKLALDYWE 289

  Fly   290 KCGIQYFNENEAELSQQEISDLPVE-NYPKDVKRPTIGCRGLVQRSL-RLLQLITRETSDWKDNV 352
            |.|.|:..|||.:|..:.....|.. .||..|:||.:|||.|:.|:| ::|..|:|:.:||....
 Frog   290 KIGSQWEKENEEDLKDKLDFSAPCPLYYPAGVQRPGLGCRELIFRNLSKILPAISRDVTDWVAGT 354

  Fly   353 RLHALKLLYQFVLHAEAAMTAKFFEIYGDLAHACIDHVAEVNAEAAKVADLMGRLLSYDAWIDHG 417
            |:.|.:||...:||.|..:|.....:...|..:|:|...:|...:.|.|:|:|..::.:.::...
 Frog   355 RIKASQLLAVLLLHGEDHITQHMELLLSTLYRSCLDEEPQVVINSVKSAELIGTFVNPEVFLKLI 419

  Fly   418 FDGLERNARESYMRCFYHMFT--ASLGGTYEQLMR--LAKLLRCTDYSH----TLKPGFQHYILK 474
            ...|:::...|      |:.|  |.:.|...:|::  |.|:......|.    :.|..:|..:|.
 Frog   420 LPALQKSPLAS------HLMTLAACIRGCSRELLKTHLTKIASVISQSEICQGSEKVLYQEQMLC 478

  Fly   475 LLNTIVDKTLKINAGQNELEDLYESVYVC-----AIKVMALSSSLEN-VGD--------EDVNFG 525
            .:.:::...         .:|..|....|     ||.....|.||.| |.|        :.:|..
 Frog   479 CIQSLIGMC---------RQDCTEVSLPCMKVLIAILASPASESLNNKVQDTLLSLSEVQGLNGP 534

  Fly   526 QTLIEKMVKLLNTSVPKIHERWFHLALQDVINLDAALEDNAEPVMLLNGLINMCHIRATYVHDLI 590
            ..|..:.::.|...|.:.|..|...:::.:.....|:|..  |||            ...:|..:
 Frog   535 HDLYRQHMQQLLDWVSESHNHWTSYSVEQIQFEVIAVESG--PVM------------GETLHLFV 585

  Fly   591 EKVKIVFQHCCD-SAQVKIFSSLSLATLFWSKTMNVERESSTQMLSEFVSQIVEPYLTWKAGSNA 654
            ..:|...|...: ..::|:|:.||...|..|:|:|.:.:.. :....|:..::.|.|.|:||..|
 Frog   586 PILKTCLQPTREPQMRLKLFTMLSKLLLKASETVNSQGQLH-RYFESFIKNMIMPNLKWQAGRTA 649

  Fly   655 EAMRSLAMATLCALAQGAESESVEVLPSLAKYMPSLL----ED----RNVTTRHYAIKAVVYF-- 709
            .|:|::|::.|..|.|.......|||......||.::    ||    |.::.|  .|:|::..
 Frog   650 GAIRTVAVSCLWVLLQSETLTHQEVLQVEDDLMPQVITTLEEDSKMCRLMSCR--IIRALLSACE 712

  Fly   710 REMSVEDLKPLAYATMQRMDDPSAGIRILAALAMGKLKPKFAETDTEENYEKEVWDAIVKRAMDL 774
            |::..:.|..:....::|:||.|..:|..||    |....:.:..::| |::..:...::.....
 Frog   713 RQLHPDKLNKIYPELLKRLDDASDEVRAAAA----KTLSHWFKCISDE-YDRTTYKGHLEFLYRG 772

  Fly   775 LLLYHESPEKDMRAAVAVTLK 795
            ||::.:.|:..::..|...||
 Frog   773 LLVHLDDPDASLQVIVLDLLK 793

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dnaaf5	NP_731905.1	HEAT repeat	52..80	CDD:293787	8/27 (30%)
		HEAT repeat	91..124	CDD:293787	14/32 (44%)
		HEAT	141..280	CDD:441023	39/141 (28%)
		HEAT repeat	143..174	CDD:293787	8/30 (27%)
		HEAT repeat	184..214	CDD:293787	8/29 (28%)
		HEAT repeat	224..254	CDD:293787	6/29 (21%)
dnaaf5	XP_002941855.2	HEAT repeat	60..89	CDD:293787	8/28 (29%)
		HEAT repeat	99..134	CDD:293787	14/40 (35%)
		HEAT repeat	145..171	CDD:293787	8/25 (32%)
		HEAT	182..>294	CDD:441023	33/113 (29%)
		HEAT repeat	182..209	CDD:293787	8/26 (31%)
		HEAT repeat	224..251	CDD:293787	5/26 (19%)
		HEAT repeat	262..291	CDD:293787	8/28 (29%)
		HEAT repeat	680..713	CDD:293787	8/34 (24%)
		HEAT_EZ	695..747	CDD:463906	14/57 (25%)
		HEAT repeat	722..748	CDD:293787	8/29 (28%)
		HEAT repeat	766..792	CDD:293787	4/25 (16%)