Protein Alignment Ir8a and GLR1.3

DIOPT Version :9

• Sequence 1: NP_727328.1
• Gene: Ir8a / 31867
• FlyBaseID: FBgn0052704
• Length: 936
• Species: Drosophila melanogaster
• Sequence 2: NP_199652.1
• Gene: GLR1.3 / 834896
• AraportID: AT5G48410
• Length: 860
• Species: Arabidopsis thaliana
• Alignment Length: 879
• Identity: 171/879 - (19%)
• Similarity: 303/879 - (34%)
• Gaps: 282/879 - (32%)

  Fly     8 LLLALRFAGSEVLKITFWIEPVQRAEFD-TDIAMVLKELD----------------ALRLDVKVD 55
            |:.|...:.||...||.:|.     .|| ..:|:|.::.|                .:|:..||.
plant   150 LIQATHDSTSEAKGITSFIN-----VFDWNSVALVYEDHDDWRESMQLLVEHFHENGVRVQSKVG 209

  Fly    56 DTTLTLTRSEDGL--DMQRFCEILSTVGASAVIDLTYSHWEEGYNLVRSLGI---GYVRL--ERI 113
               .|::.|||.:  .:|:..::.:||....:.::..:|.   :...|.||:   |:|.:  .:.
plant   210 ---FTVSSSEDFVMGRLQQLKDLGTTVFVVHLSEVIATHL---FPCARRLGLMGDGFVWILTAKT 268

  Fly   114 MRPFLDMFGDFMRQKRANNVAMVFMNARDAVEAMQQMLVGYPFRTLIMDASQTDPGQHFLERIRS 178
            |..|.:...||.:|               |:|.    :||  |::.|..:.:.   |:|..|.|.
plant   269 MNSFHENIDDFTKQ---------------AMEG----VVG--FKSYIPMSIEL---QNFTLRWRK 309

  Fly   179 LRPAPTYIALFARAAAMNGIFEKVQKADLFQRPLE--WHFVFLDTRDRVFKYRRQAELC------ 235
            ..|                    |::|:|.:..:.  |      ..|..|...|.||:.
plant   310 SLP--------------------VEEAELTRLSISGIW------AHDIAFALARAAEVIRMPNVT 348

  Fly   236 ---------TRFT-------LNPRAICRSMPMPDLYCGSGFTMQRAMLLNVLRSLINAAQVSPGY 284
                     |||.       ||.:.:..:  ..::....|.:.:|...||...|..|...:|
plant   349 STLLEEITKTRFNGLSGDFQLNDKKLLSN--KFEIINMIGSSERRVGFLNSNGSFSNRRHLS--- 408

  Fly   285 PLAIYQDCNATASSSEVSDPLEKDDYNWLDMVHWSNFLAYAPPLPHIQDQFQSPVPGLTFAVNIS 349
                                   ..:|.|:.:.|....|.:|....:.|
plant   409 -----------------------STHNKLETIIWPGGSAQSPKGTSLID---------------- 434

  Fly   350 AGYYSSEHEAKTDLAAWSSVGEMRLLNETISPARRFFRIGTAESIPWSYLRREEGTGELIRDRSG 414
                             |...::|:|   ::.:.||.|:...|:.|        .|.||
plant   435 -----------------SDRKKLRVL---VTSSNRFPRLMKVETDP--------VTNEL------ 465

  Fly   415 LPIWEGYCIDFIIRLSQKLNFEFEIVAPEVGHMGELN-------ELGEWDGVVGDLVRGETDFAI 472
              |.||:||:.........|:|.|.: |.:......|       :..::|..|||:.
plant   466 --IVEGFCIEVFRASISPFNYEVEYI-PWLNGSNYDNLAYALHSQKDKYDAAVGDIT-------- 519

  Fly   473 AALKMYSEREEVIDFLPPYYEQTGISIAIRKPVRRTSLFKFMTVLRLEVWLSIVAALVGTAIMIW 537
                :.|.|...:||..|:.|. |:.|.   .|:..|::.|...|..::|::.....|.|.:::|
plant   520 ----ITSNRSTYVDFTLPFTEM-GLGIV---AVKERSMWVFFQPLTPDLWITSAFFFVLTGVIVW 576

  Fly   538 FMDKYSPYSSRNNRQAYPYACREFTLRESFWFALTSFTPQGGGEAPKAISGRMLVAAYWLFVVLM 602
            .:::   ..::..:.::|.     .:....||..::.. ....|..|....|.:|.. |:|.||:
plant   577 LIER---AENKEFQGSWPQ-----QIGVVLWFGFSTLV-YAHREKLKHNLSRFVVTV-WVFAVLI 631

  Fly   603 L-ATFTANLAAFLTVERMQTPVQSLEQLARQSRINYTVVKDSDTH---QYFVNMKFAEDTLYRMW 663
            | |::||.|.:.:||:                :|.:...:|...|   ....|:.....:| |..
plant   632 LTASYTATLTSMMTVQ----------------QIRFNSNEDYVGHLSGSLIANVALTSSSL-RAM 679

  Fly   664 KELALNASKDFKKFRIWDYPIKEQYGHILLAINSSQPVADAKEGFANVDAHENADYAFIHDSAEI 728
            :.|.||::.|              |...||  |.:......:..:..|...||..:.|:     :
plant   680 RSLGLNSAAD--------------YAQALL--NKTVSFVVDELPYLKVVLGENPTHFFM-----V 723

  Fly   729 KYEITRNCNLTEVGEVFAEQPYAVAVQQGSHLGDELSYAILELQKDRFFEELKAKYWNQSNLPNC 793
            |.:.|.|             .:....|:|..|...:|..|.:|:......|:: |.|..:.|| .
plant   724 KTQSTTN-------------GFGFMFQKGFELVPNVSREISKLRTSEKLNEME-KRWFDNQLP-Y 773

  Fly   794 PLSEDQEGITLESLGGVF--IATLFGLVLAMMTL 825
            ...:....|||....|:|  |...|...||::.:
plant   774 TTDDTSNPITLYRFRGLFIIIGVSFAFALAVLVI 807

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir8a	NP_727328.1	PBP2_iGluR_putative	383..786	CDD:270435	85/413 (21%)
		Lig_chan	520..818	CDD:278489	61/303 (20%)
GLR1.3	NP_199652.1	PBP1_GABAb_receptor	43..405	CDD:107361	64/317 (20%)
		ANF_receptor	57..385	CDD:279440	58/297 (20%)
		GluR_Plant	438..767	CDD:270404	87/426 (20%)
		Lig_chan	559..798	CDD:278489	60/301 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	82	0.746	Domainoid score	I2907
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	1	1.000	-	-		mtm1027
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.910