DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Ir8a and GLR2.8

DIOPT Version :9

Sequence 1:NP_727328.1 Gene:Ir8a / 31867 FlyBaseID:FBgn0052704 Length:936 Species:Drosophila melanogaster
Sequence 2:NP_001324459.1 Gene:GLR2.8 / 817459 AraportID:AT2G29110 Length:948 Species:Arabidopsis thaliana


Alignment Length:445 Identity:99/445 - (22%)
Similarity:185/445 - (41%) Gaps:93/445 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   407 ELIRDRSGLPIW-----EGYCIDFIIRLSQKLNFEFEIVAPEVGHMGELNELGEWDGVVGDLVRG 466
            |:|.|    ||.     :||.||......:||.:.   |.|:.......::  ::|.:|..:..|
plant   471 EVITD----PITNITTPKGYAIDIFEAALKKLPYS---VIPQYYRFESPDD--DYDDLVYKVDNG 526

  Fly   467 ETDFAIAALKMYSEREEVIDFLPPYYEQTGISIAIRKPVR---RTSLFKFMTVLRLEVWLSIVAA 528
            ..|..:..:.:.:.|....||..||.| :|:|:.:  |||   ..:.:.|:....|::|::....
plant   527 TLDAVVGDVTITAYRSLYADFTLPYTE-SGVSMMV--PVRDNENKNTWVFLKPWGLDLWVTTACF 588

  Fly   529 LVGTAIMIWFMDKYSPYSSRNNRQAYPYACREFTLRESFWFALTSFTPQGGGEAPKAISG-RMLV 592
            .|....::|..:    :....:.:..|:    ..:..||||   ||:........|.:|. ...|
plant   589 FVLIGFVVWLFE----HRVNTDFRGPPH----HQIGTSFWF---SFSTMVFAHREKVVSNLARFV 642

  Fly   593 AAYWLFVVLMLA-TFTANLAAFLTVERMQTPVQSLEQLARQSRINYTVVKDSD----THQYFVNM 652
            ...|.||||:|. ::||||.:||||:|.|....:::.|          :|:.|    .|..||. 
plant   643 VVVWCFVVLVLTQSYTANLTSFLTVQRFQPAAINVKDL----------IKNGDYVGYQHGAFVK- 696

  Fly   653 KFAEDTLYRMWKELALNASKDFKKFRIWDYPIKEQYGHILLAINSSQPVADAKEGFANVDAHENA 717
                                        |:.|||.:.     ::..:|...::|..|.: ::.:.
plant   697 ----------------------------DFLIKEGFN-----VSKLKPFGSSEECHALL-SNGSI 727

  Fly   718 DYAFIHDSAEIKYEITRNCNLTEVGE-VFAEQPYAVAVQQGSHLGDELSYAILELQKDRFFEELK 781
            ..|| .:.|.::..:::.|:...:.| .|....:..|..:.|.|..::|.|||.:.:....:.::
plant   728 SAAF-DEVAYLRAILSQYCSKYAIVEPTFKTAGFGFAFPRNSPLTGDVSKAILNVTQGDEMQHIE 791

  Fly   782 AKYWNQSNLPNCP-----LSEDQEGITLESLGGVFIATLFGLVLAMMTLGMEVLY 831
            .|::.:.|  :||     ||.::  ::|.|..|:|:.......||::......||
plant   792 NKWFMKQN--DCPDPKTALSSNR--LSLRSFWGLFLIAGIASFLALLIFVFLFLY 842

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ir8aNP_727328.1 PBP2_iGluR_putative 383..786 CDD:270435 86/393 (22%)
Lig_chan 520..818 CDD:278489 65/309 (21%)
GLR2.8NP_001324459.1 PBP1_GABAb_receptor_plant 35..419 CDD:380645
GluR_Plant 454..795 CDD:270404 86/392 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 1 1.000 82 0.746 Domainoid score I2907
eggNOG 1 0.900 - - E1_KOG1052
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000021
OrthoInspector 1 1.000 - - mtm1027
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR18966
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
76.910

Return to query results.
Submit another query.