Protein Alignment Ir8a and CG11155

DIOPT Version :10

• Sequence 1: NP_727328.1
• Gene: Ir8a / 31867
• FlyBaseID: FBgn0052704
• Length: 936
• Species: Drosophila melanogaster
• Sequence 2: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Alignment Length: 898
• Identity: 207/898 - (23%)
• Similarity: 361/898 - (40%)
• Gaps: 234/898 - (26%)

  Fly    37 DIAMVLKELDALRLDVKVDDTTLTLTRSEDGLD-------------MQRFCEILSTVGASAVIDL 88
            ||..|.:: |:.|...||      .::.|.|:.             :|..||..........|||
  Fly    84 DIEYVPRD-DSFRTTKKV------CSQLEAGVQAIFGPTDALLASHVQSICEAYDIPHIEGRIDL 141

  Fly    89 TYSHWEEGYNLVRS---LGIGYVRLERIMRPFLDMFGDFMRQKRANNVAMV-------FMNARDA 143
            .|:..|...||..|   |.:.|              .|.|.......||::       |.....:
  Fly   142 EYNSKEFSINLYPSHTLLTLAY--------------RDIMVYLNWTKVAIIYEEDYGLFNLMHSS 192

  Fly   144 VEAMQQMLVGYPFRTLIMDASQTDPGQHFLERIRSLRPAPTY-IALFARAAAMNGIFEKVQKADL 207
            .|...:|.:           .|..| ..:.:.:|::|....| |.:....:.:...|..:.:..:
  Fly   193 TETKAEMYI-----------RQASP-DSYRQVLRAIRQKEIYKIIVDTNPSHIKSFFRSILQLQM 245

  Fly   208 FQRPLEWHFVF----LDTRD-RVFKYRRQAELCTRFTLNPRAICRSMPMPDLYCGSGFTMQRAML 267
            ...  .:|::|    |:|.| ..|:|.         ::|                  .|..|.:.
  Fly   246 NDH--RYHYMFTTFDLETYDLEDFRYN---------SVN------------------ITAFRLVD 281

  Fly   268 LNVLRSLINAAQVSPGYPLAIYQDCNATASSSEVSDPLEKDDYNWLDMVHWSNFLAYAPPLPHIQ 332
            ::..|.|                         ||.:.::|..:|.||.::.|         |:||
  Fly   282 VDSKRYL-------------------------EVINQMQKLQHNGLDTINGS---------PYIQ 312

  Fly   333 -------DQFQSPVPGLTFAVNIS--AGYYSSEHEAKTDLAAWSSVGEMRLLNETISPA------ 382
                   |...:...||.| :|:.  ..:|.......:|......:.....:|..|:..
  Fly   313 TESALMFDSVYAFANGLHF-LNLDNHQNFYIKNLSCTSDQTWNDGISLYNQINAAITDGLTGTVQ 376

  Fly   383 -----RRFFRI--------------------GTAESIPWSY------------LRREEGTGELIR 410
                 |..|::                    |...|.|.::            :.|||....:::
  Fly   377 FVEGRRNIFKLDILKLKQEKIQKVGYWHPDDGVNISDPTAFYDSNIANITLVVMTREERPYVMVK 441

  Fly   411 DRSGLP---IWEGYCIDFIIRLSQKLNFEFEI-VAPEVGHMGELNELGEWDGVVGDLVRGETDFA 471
            :...|.   .:||:|||.:..::.::.|:::| :.|:..:...:.|...|:|:|.:|:....|.|
  Fly   442 EDKNLTGNLRFEGFCIDLLKAIATQVGFQYKIELVPDNMYGVYIPETNSWNGIVQELMERRADLA 506

  Fly   472 IAALKMYSEREEVIDFLPPYYEQTGISIAIRKPVRR-TSLFKFMTVLRLEVWLSIVAALVGTAIM 535
            :|::.:...||.||||..|:. ..||.|..:.|..: |.||.||..|.:|:||.::||.:..:..
  Fly   507 VASMTINYARESVIDFTKPFM-NLGIGILFKVPTSQPTRLFSFMNPLAIEIWLYVLAAYILVSFA 570

  Fly   536 IWFMDKYSPYSSRNNRQAYPYAC--------REFTLRESFWFALTSFTPQGGGEAPKAISGRMLV 592
            ::.|.::|||..:|     |:.|        .:|::..||||...:|..||.|..|||.|.|::.
  Fly   571 LFVMARFSPYEWKN-----PHPCYKETDIVENQFSISNSFWFITGTFLRQGSGLNPKATSTRIVG 630

  Fly   593 AAYWLFVVLMLATFTANLAAFLTVERMQTPVQSLEQLARQSRINYTVVKDSDTHQYFVNMKFAED 657
            ..::.|.:::::::|||||||||||||.:|::|...||.|:.|:|..::...|..:|.:.|..
  Fly   631 GCWFFFCLIIISSYTANLAAFLTVERMISPIESASDLAEQTEISYGTLEGGSTMTFFRDSKIG-- 693

  Fly   658 TLY-RMWKELALNASKDFKKFRIWDYPIKEQYGHILLAINSSQPVADAKEGFANVDAHENADYAF 721
             :| :||:.:....:..|.|  .::..||.                 ..||          .|||
  Fly   694 -IYQKMWRYMENRKTAVFVK--TYEDGIKR-----------------VMEG----------SYAF 728

  Fly   722 IHDSAEIKYEITRNCNLTEVGEVFAEQPYAVAVQQGSHLGDELSYAILELQKDRFFEELKAKYWN 786
            :.:|..:.|.:.|:||||::|.:...:.|.:|..:||...|::|.||||||:....:.|..|:|.
  Fly   729 LMESTMLDYAVQRDCNLTQIGGLLDSKGYGIATPKGSPWRDKISLAILELQEKGIIQILYDKWWK 793

  Fly   787 QS----NLPNCPLSEDQEGITLESLGGVFIATLFGLVLAMMTLGMEVLYYKKK 835
            .:    |..:.........:.:|::||||:..|.||.||::....|..:..:|
  Fly   794 NTGDVCNRDDKSKESKANALGVENIGGVFVVLLCGLALAVVVAIFEFCWNSRK 846

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir8a	NP_727328.1	PBP2_iGluR_putative	383..786	CDD:270435	126/448 (28%)
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..413	CDD:380605	70/425 (16%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	121/406 (30%)
		Lig_chan	554..828	CDD:459656	92/310 (30%)