Protein Alignment Ir8a and clumsy

DIOPT Version :10

• Sequence 1: NP_727328.1
• Gene: Ir8a / 31867
• FlyBaseID: FBgn0052704
• Length: 936
• Species: Drosophila melanogaster
• Sequence 2: NP_001036373.1
• Gene: clumsy / 35394
• FlyBaseID: FBgn0026255
• Length: 1002
• Species: Drosophila melanogaster
• Alignment Length: 907
• Identity: 230/907 - (25%)
• Similarity: 377/907 - (41%)
• Gaps: 241/907 - (26%)

  Fly    34 FDTDIAMVLKEL----DALRLDVKVDDTTLTLTRSEDGLDMQRF----------CEILSTVGASA 84
            ::||     |||    |.|::...:.:.| |:.:...|.|.:.|          |.||.....:.
  Fly   161 YETD-----KELQQLQDILQVGEPISNPT-TVKQLGPGDDHRPFLKEIKLSTDNCLILHCAPDNL 219

  Fly    85 VIDLTYSHWEEGYNLVRSLGIGYVRLERIMRPFLDM----FGDFMRQKRANNVAMVFMNARDAVE 145
            :..|..:      |.::.||    ..:.:..|.||.    ||: :....||...:..|:..|
  Fly   220 LKILQQA------NELKMLG----EYQSVFIPLLDTHSIDFGE-LSGVEANITTVRLMDPSD--- 270

  Fly   146 AMQQMLVGYPFRTLIMDASQTD--PGQHFL---ERIRS----LRPAPTYIALFARAAAMNGIFEK 201
                    :..:.::.|..:.:  .|::|.   .|::|    |..|   :.||::.....||||:
  Fly   271 --------FHVKNVVHDWEEREKREGRYFKVDPNRVKSQMILLNDA---VWLFSKGLTELGIFEE 324

  Fly   202 VQKADL-FQRPLEWHFVFLDTRDRVFKY--RRQAELCT-RFTLNPRAICRSMPMPDLYCGSGFTM 262
            :...|| .:|...|.|     ..|:.::  .|..|..| |...|... .||.          ||:
  Fly   325 LTAPDLECRRKKPWPF-----GKRIIEFIKARSEETSTGRIDFNENG-QRSF----------FTL 373

  Fly   263 QRAMLLNVLRSLINAAQVSPGYPLAIYQDCNATASSSEVSDPLEKDDYNWLDMVHWSNFLAYAPP 327
             |.|.||           |.|:                            ||:..|
  Fly   374 -RFMELN-----------SDGF----------------------------LDLATW--------- 389

  Fly   328 LPHIQDQFQSPVPGLTFAVNISAGYYSSEHEAKTDLAAWSSVGEMRLLNETISPARRFFRIGTAE 392
                     .||.||        ...:.:.|::      ..||: :|.|:|       |.:.:..
  Fly   390 ---------DPVNGL--------DVLNDDEESE------KRVGQ-KLSNKT-------FIVSSRL 423

  Fly   393 SIPWSYLRREEGTGELIRDRSGLPIWEGYCIDFIIRLSQKLNFEFEIVAPEVGHMGELNELGE-W 456
            ..|:..| ||...||::   :|...:|||.||.|..:::.|||:||......|..|.||::.: |
  Fly   424 GAPFLTL-REPQEGEIL---TGNSRYEGYSIDLINEIAKMLNFKFEFRMSPDGKYGALNKVTQTW 484

  Fly   457 DGVVGDLVRGETDFAIAALKMYSEREEVIDFLPPYYEQTGISIAIRK-PVRRTSLFKFMTVLRLE 520
            ||:|..|:.|..|..|..|.|.|.|.:.:||.||:. ..||||...| |...|.||.|::...|:
  Fly   485 DGIVRQLIDGNADLGICDLTMTSSRRQAVDFTPPFM-TLGISILFSKPPTPPTDLFSFLSPFSLD 548

  Fly   521 VWLSIVAALVGTAIMIWFMDKYSPYSSRNNRQAYPYACRE-------FTLRESFWFALTSFTPQG 578
            ||:.:.:|.:..:::::.:.:.:|....|     |:.|:|       :::..:.|.::.|...||
  Fly   549 VWIYMGSAYLFISLLLFALARMAPDDWEN-----PHPCKEPEEVENIWSIMNTTWLSIGSLMGQG 608

  Fly   579 GGEAPKAISGRMLVAAYWLFVVLMLATFTANLAAFLTVERMQTPVQSLEQLARQSRINYTVVKDS 643
            ....|||.|.|::...:|.|.::||.::|||||||||..|....:.|.|.||.||:|.|..:...
  Fly   609 CDILPKAASTRLVTGMWWFFALMMLNSYTANLAAFLTNSRQANSINSAEDLAAQSKIKYGAMAGG 673

  Fly   644 DTHQYFVNMKFAEDTLYRMWKELALNASKDFKKFRIWDYPIKEQYGHILLAINSSQPVADAK--- 705
            .|..:|.:..|:  |..:||                             .|:.|:.|....|
  Fly   674 STMGFFRDSNFS--TYQKMW-----------------------------TAMESASPSVFTKTND 707

  Fly   706 EGFANVDAHENADYAFIHDSAEIKYEITRNCNLTEVGEVFAEQPYAVAVQQGSHLGDELSYAILE 770
            ||...|...:|. |||:.:|..::|.:.|.|:|.::|.....:.|.:|:...|....::|.|:|:
  Fly   708 EGVERVQKGKNL-YAFLMESTTLEYNVERKCDLVQIGGWLDYKSYGIAMPFNSPYRKQISAAVLK 771

  Fly   771 LQKDRFFEELKAKYWNQSN-LPNCPLSEDQEGIT----LESLGGVFIATLFGLVLAMMTLGMEVL 830
            |.:.....|||.|:|.:.: ..||..|::..|.|    ||::||||:....|| |:.|.||....
  Fly   772 LGELGQLAELKRKWWKEMHGGGNCEKSDEDGGDTPELGLENVGGVFLVLGLGL-LSAMVLGCTEF 835

  Fly   831 YYKKKQNALE--------------------ITQVRPVNDSSGSGGNSSTAPPTATSTTKQAW 872
            .:..|..|:|                    || .:||:.||.||.::|::  :::|.:|.::
  Fly   836 LWNVKSVAIEEKISLKEAFKSEALFAARIWIT-TKPVHTSSESGSSNSSS--SSSSRSKHSF 894

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir8a	NP_727328.1	PBP2_iGluR_putative	383..786	CDD:270435	123/414 (30%)
clumsy	NP_001036373.1	PBP1_iGluR_Kainate	27..397	CDD:380605	69/348 (20%)
		PBP2_iGluR_Kainate	414..787	CDD:270432	125/421 (30%)