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Protein Alignment Ir8a and Gria2

DIOPT Version :9

Sequence 1:	NP_727328.1	Gene:	Ir8a / 31867	FlyBaseID:	FBgn0052704	Length:	936	Species:	Drosophila melanogaster
Sequence 2:	NP_001077280.1	Gene:	Gria2 / 29627	RGDID:	61862	Length:	883	Species:	Rattus norvegicus

Alignment Length:	568	Identity:	155/568 - (27%)
Similarity:	273/568 - (48%)	Gaps:	86/568 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   342 LTFAVNISAGYYSSEHEAKTD----LAAWSSVGEMRLL-------NETISPARRFFRIGTAESIP 395
            :.:.:||.        |.||:    :..||.|.:|.:.       |:|.....:...:.|....|
  Rat   369 INYTINIM--------ELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTILESP 425

  Fly   396 WSYLRREEGTGELIRDRSGLPIWEGYCIDFIIRLSQKLNFEFEIVAPEVGHMGELN-ELGEWDGV 459
            :..:::..   |::   .|...:||||:|....:::...|::::.....|..|..: :...|:|:
  Rat   426 YVMMKKNH---EML---EGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGM 484

  Fly   460 VGDLVRGETDFAIAALKMYSEREEVIDFLPPYYEQTGISIAIRKPVR-RTSLFKFMTVLRLEVWL 523
            ||:||.|:.|.|||.|.:...|||||||..|:. ..||||.|:||.: :..:|.|:..|..|:|:
  Rat   485 VGELVYGKADIAIAPLTITLVREEVIDFSKPFM-SLGISIMIKKPQKSKPGVFSFLDPLAYEIWM 548

  Fly   524 SIVAALVGTAIMIWFMDKYSPY--------SSRNNRQAYPYACREFTLRESFWFALTSFTPQGGG 580
            .||.|.:|.:::::.:.::|||        ..|..:.:  .:..||.:..|.||:|.:|..||..
  Rat   549 CIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSS--ESTNEFGIFNSLWFSLGAFMRQGCD 611

  Fly   581 EAPKAISGRMLVAAYWLFVVLMLATFTANLAAFLTVERMQTPVQSLEQLARQSRINYTVVKDSDT 645
            .:|:::|||::...:|.|.:::::::|||||||||||||.:|::|.|.|::|:.|.|..:....|
  Rat   612 ISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGST 676

  Fly   646 HQYFVNMKFAEDTLYRMWKELALNASKDFKKFRIWDYPIKEQYGHILLAINSSQP---VADAKEG 707
            .::|...|.|.                 |.|  :|.|            :.|::|   |....||
  Rat   677 KEFFRRSKIAV-----------------FDK--MWTY------------MRSAEPSVFVRTTAEG 710

  Fly   708 FANVDAHENADYAFIHDSAEIKY-EITRNCNLTEVGEVFAEQPYAVAVQQGSHLGDELSYAILEL 771
            .|.| ......||::.:|...:| |..:.|:..:||.....:.|.:|..:||.||:.::.|:|:|
  Rat   711 VARV-RKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKL 774

  Fly   772 QKDRFFEELKAKYWNQSNLPNC-----PLSEDQEGITLESLGGVFIATLFGLVLAMMTLGMEVLY 831
            .:....::||.|:|....  .|     ...|....::|.::.|||...:.||.|||:...:|..|
  Rat   775 NEQGLLDKLKNKWWYDKG--ECGSGGGDSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCY 837

  Fly   832 YKKKQNALEITQVRPVNDSSGSGGNSSTAPPTATSTTKQAWHIPVLEA 879
            ..:.:.........|.|.:..|..||..     .:|.|:.:::..:|:
  Rat   838 KSRAEAKRMKVAKNPQNINPSSSQNSQN-----FATYKEGYNVYGIES 880

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.