Protein Alignment Ir8a and W02A2.5

DIOPT Version :9

• Sequence 1: NP_727328.1
• Gene: Ir8a / 31867
• FlyBaseID: FBgn0052704
• Length: 936
• Species: Drosophila melanogaster
• Sequence 2: NP_502564.2
• Gene: W02A2.5 / 189098
• WormBaseID: WBGene00012190
• Length: 487
• Species: Caenorhabditis elegans
• Alignment Length: 459
• Identity: 85/459 - (18%)
• Similarity: 168/459 - (36%)
• Gaps: 114/459 - (24%)

  Fly   420 GYCIDFIIRLSQKLNFE-FEIVAPE-VGHM--GELNELGEWDGVVGDLVRGETDFAIAALKMYSE 480
            |:.::.:..::..|.:| ..:|.|. ||.:  |.|.:.|.|.||:|.|..|..|   |...||.:
 Worm    38 GWTMEVLKMITDSLKWEIIPVVTPTIVGGLDWGTLQKNGTWSGVLGYLQNGTAD---AVALMYQK 99

  Fly   481 ---REEVIDFLPPYYEQTGISIAIRKPVRRTSL----FKFMTVLRLEVWLSIVAALV-------- 530
               |.|..::..|......:.:|.:|.....|:    ||..:|   ||||.::|:||
 Worm   100 TDTRNEYFEYSYPVTNVQPVFVARKKTETLGSVLWNAFKPFSV---EVWLCLLASLVLNLLIMIA 161

  Fly   531 --GTAIMIWFMDKYSPYSSRNNRQAYPYACREFTLRESFWFAL-TSFTPQGGGEAPKAISGRMLV 592
              |....:.|..::.|:                   |..|..: .....:........:||.:::
 Worm   162 ISGIEFKLLFRSRFRPW-------------------EMLWHVVQLQLDEKSDDMLFYTLSGNIVL 207

  Fly   593 AAYWLFVVL----MLATFTANLAAFLTVERMQTPVQSLEQLARQ-SRINYTVVKDSDTHQYFVNM 652
               ::|.:|    ::..:...|...|.......|..:.:::.:. ....|.:..:...:.||.::
 Worm   208 ---FVFALLQSGILIEVYKGMLLTALITSNGDNPFANADEMIKLIGEKKYHLTTNYMGNWYFDDL 269

  Fly   653 KFAEDTLYRMWKELALNASKDFKKFRIWDYPIKEQYGHILLAINSSQPVADAKEGFANVDAHENA 717
            :.::                             :|:...|.|..:|.||..|....|.:|..::.
 Worm   270 QHSD-----------------------------QQHFVSLRAATASNPVIPAASVSAALDLVDSG 305

  Fly   718 DYAFIHDSAEIKYEITR-NCNLTEVGE---------VFAEQPYAVAVQQGSHLGDELSYAILELQ 772
            .|.:......:..:::: .||...|.:         ||.:....:|         |.:..|  :.
 Worm   306 KYIYPIQQDSLAMQMSKERCNYVYVSDGMPQVSSFFVFTKNFSGIA---------EFNTQI--IM 359

  Fly   773 KDRFFEELKAKYWNQ----SNLPNCPLSED-----QEGITLESLGGVFIATLFGLVLAMMTLGME 828
            ...|.:....||:|:    ..:|.|.::|.     .:.:.:||:.|||.....|:..::|....|
 Worm   360 NQAFIQRTFNKYFNEGFKLGFIPKCEVTEPTASDATKPLDIESVIGVFTIGALGVAASLMVFVFE 424

  Fly   829 VLYY 832
            :.:|
 Worm   425 IYHY 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir8a	NP_727328.1	PBP2_iGluR_putative	383..786	CDD:270435	72/402 (18%)
		Lig_chan	520..818	CDD:278489	52/332 (16%)
W02A2.5	NP_502564.2	Lig_chan-Glu_bd	<36..86	CDD:214911	14/47 (30%)
		Periplasmic_Binding_Protein_Type_2	<74..>124	CDD:304360	15/52 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810