Protein Alignment Ir8a and Ir93a

DIOPT Version :10

• Sequence 1: NP_727328.1
• Gene: Ir8a / 31867
• FlyBaseID: FBgn0052704
• Length: 936
• Species: Drosophila melanogaster
• Sequence 2: XP_061512014.1
• Gene: Ir93a / 1272000
• VectorBaseID: AGAMI1_007780
• Length: 876
• Species: Anopheles gambiae
• Alignment Length: 1011
• Identity: 188/1011 - (18%)
• Similarity: 325/1011 - (32%)
• Gaps: 359/1011 - (35%)

  Fly    40 MVLKELDALRLDVKVDDTTLTLTRSEDGLDMQRFCEILSTVGASAVI-DLTYSHWEEGYNLVRSL 103
            ::|..|..||.|..|.|.               |..:|||..:.|:| |..|            |
Mosquito    12 LLLLLLLVLRPDPAVGDD---------------FPSLLSTNASMAIILDREY------------L 49

  Fly   104 GIGYVR--------LERIMRPFLDMFGDFMRQ--------KRANNVAMVFMNARDAVEAMQQMLV 152
            |..|.|        :|:::|..|...|..::.        ||..:..:...:.::..:..|:.:
Mosquito    50 GADYERTLDETKNVVEKLIREHLKNGGLIVKYYSWTSINLKRDFSAVLSVSSCKNTWDIYQEAV- 113

  Fly   153 GYPFRTLIMDASQTDPGQHFLERIRSLRPAPTYIALFARAAAMNG--IFEKVQKADL---FQRPL 212
                |..::..|.|||....|         ||..|:....:..:|  .|::|.:..|   ..|.:
Mosquito   114 ----RERLVMLSITDPDCPRL---------PTNNAIMIPRSDGSGSNAFDEVSQIILDMKSSRAI 165

  Fly   213 EWHFVFLDTRDRVFKYRRQAELC----------------TRFTLNP--------RAICRS-MPMP 252
            .||...| ..|:|  |..:...|                |.|.:|.        :.|.|: :.:|
Mosquito   166 NWHTATL-LYDQV--YDAEISRCILSLLEDREGIKPLTLTEFKINAPTHSWEKRKEIRRTLLGIP 227

  Fly   253 DLYCG------------------------------------------SGFTMQRAM--------- 266
            ..|.|                                          |.||.|..:
Mosquito   228 TAYTGRNFIAIVNIATLTLLMEISKDLKLVNPFAQWLYLIPNTEKANSNFTTQSTLINEGDNVAF 292

  Fly   267 ----------------------LLNVLRS---LINAAQVSPGY---------------------- 284
                                  ||:.:||   ||...||..|.
Mosquito   293 VYNSGSKAQNCTVSVLCYIESYLLHFIRSLSKLIREEQVVFGQISDEEWEIIRPSKQERKTKFLQ 357

  Fly   285 ----PLAIYQDCNATA----SSSEV-------------SDPLEKDDYNWLDMVHWS---NFLAYA 325
                .:....:||..:    .|:|.             :|..|:..|..||:.:||   .|:...
Mosquito   358 MIKAAITSKDECNKCSQWKIQSAETWGYVYRTDFLTDGADLQERRKYTMLDIGYWSPQDGFMLTD 422

  Fly   326 PPLPHIQDQFQSPVPGLTFAVNISAGYYSSEHEAKTDLAAWSSVGEMRLLNETISPARRFFRIGT 390
            ...||.|..|:          .:...:||..:.
Mosquito   423 ALFPHTQYGFR----------GVQLIFYSYHNP-------------------------------- 445

  Fly   391 AESIPWSYLRREEGTGELIRDRSGLP-IWEGYCIDFIIRLSQKLNFEFEIVAPEVGHMGELNELG 454
                ||.::...:         ||.| |..|...|.:..||:||||.:.:|   :....|:|
Mosquito   446 ----PWQFVAYND---------SGSPVISSGVVYDILNELSRKLNFTYTMV---ISQPAEIN--- 491

  Fly   455 EWDGVVGDLVRGETDFAIAALKMYS---------------------------EREEVIDFLPPYY 492
                  |.||.|.|. ::..||..|                           ::::.:.|..|..
Mosquito   492 ------GSLVEGNTS-SVYDLKTISSDIPQEIFSTLVNNKILLAAVGATVNEKQKKFVSFTDPIS 549

  Fly   493 EQTGISIAIRKPVRRTSLFKFMTVLRLEVWLSIVAALVGTAIMIWFMDKYSPYSSRNNRQAYPYA 557
            .|| .|..|.:|...:.:..|::....:.||.:.||:.....::..::|.|||...:|:   |..
Mosquito   550 IQT-YSFVISRPRELSRVLLFLSPFGSDTWLCLAAAVALMGPILCAINKLSPYYEVHNK---PTD 610

  Fly   558 CREFTLRESFWFALTSFTPQGGGEAPKAISGRMLVAAYWLFVVLMLATFTANLAAFLTVERMQTP 622
            .....:...||:...:...|||...|.|.|||:::..:||.|::::.|:..||.||||..::..|
Mosquito   611 TGLGKVNNCFWYIYGALLQQGGLYLPYADSGRIIIGTWWLVVLVIVTTYCGNLVAFLTFPKIDIP 675

  Fly   623 VQSLEQLARQSR-INYTVVKDSDTHQYFVNMKFAEDTLYRMWKELALNASKDFKKFRIWDYPIKE 686
            |..:.||.|..| :.:::.:.:...:..  |...|....:::|...:               |.|
Mosquito   676 VNRVMQLLRNDRGMTWSIRRGTFLEEML--MDSTEPKYMQLYKGSQI---------------IGE 723

  Fly   687 QYGHILLAINSSQPVADAKEGFANVDAHENADYAFIHDSAEIKYEITRNCNLTEVGEVFAEQPYA 751
            ....::..|.:.|.|        ::|...|..|..     :.::..|..|:.....:.|.::..|
Mosquito   724 LTDELVERIEAGQHV--------HIDWRNNLRYLM-----KRQFLRTDRCDFALSTDEFLDEQIA 775

  Fly   752 VAVQQGSHLGDELSYAILELQKDRFFEELKAKYWNQSNLP---NCP-----LSEDQEGITLESLG 808
            :.:.:.|...:.::..|..:.:..|.:...|:|     ||   .|.     :......:....:.
Mosquito   776 LVMPKDSPYLELVNEEIKRMHQFGFIQRWVAQY-----LPAKDKCSGTGRVMDVQNHTVNSSDMA 835

  Fly   809 GVFIATLFGLVLAMMTLGME--VLYYKKKQNALEIT 842
            |.:...|.|.|..:.....|  |.:|:|.:.|...|
Mosquito   836 GSYWILLLGFVSGLFVFVCEFAVAWYRKSRAAQAAT 871

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir8a	NP_727328.1	PBP2_iGluR_putative	383..786	CDD:270435	89/431 (21%)
Ir93a	XP_061512014.1	None