Protein Alignment Ir8a and grin3b

DIOPT Version :9

• Sequence 1: NP_727328.1
• Gene: Ir8a / 31867
• FlyBaseID: FBgn0052704
• Length: 936
• Species: Drosophila melanogaster
• Sequence 2: XP_017952374.2
• Gene: grin3b / 100497172
• XenbaseID: XB-GENE-990106
• Length: 1005
• Species: Xenopus tropicalis
• Alignment Length: 917
• Identity: 196/917 - (21%)
• Similarity: 325/917 - (35%)
• Gaps: 260/917 - (28%)

  Fly     9 LLALRFAGSEVLKITFWIEPVQRAEFDTDIAMVLKELDALRLDVKVDDTTLTLTRSEDGLDMQRF 73
            ||.|.|. |..|:|.|    :...|.:..:.:..|....|::|        |.:..|:.:|:  |
 Frog   113 LLQLEFL-SSFLEIPF----ISILEQEQIVPLATKNPFHLQMD--------TQSSVENLMDI--F 162

  Fly    74 CEILSTVGASAVIDLTYSHWEEGYNLVRSLGIGYVRLER-----------IMRPFLDMFGDFMRQ 127
            ..:|.......|..:|...|:.. ::.|.|......:.|           .:.|||....:.|:.
 Frog   163 FSVLQNSSWEEVDIITCHPWDSA-SIQRYLTSNTTLVSRTILNIHPVDESALVPFLQQHFESMKN 226

  Fly   128 KR---------ANNVAMVFMNARD-AVEAMQ-QMLVGYPFRTLIMDASQTDPGQHFLERIRSLRP 181
            .:         |...::||..||| .:||.: ..::|:|.....|......||
 Frog   227 PQFPMLLYGCDARRSSLVFRVARDCGLEAHEFHWMIGHPLNGEEMTTEGMPPG------------ 279

  Fly   182 APTYIALFARAAAMNGIFEKVQKADLFQRPLEWHFVFLDTRDRVFKYRRQAELCTRFTLNPRAIC 246
                  |.|.........||              |:    ||.|             .|..|||.
 Frog   280 ------LLAYGEVSRPTMEK--------------FI----RDAV-------------GLVTRAIS 307

  Fly   247 RSMPM-PDLYCGSGFTMQRAMLLNVLRSLINAAQVSPGYPLAIYQDCNATASSSEVSDPLEKDDY 310
            .::.: ||              |.:::|::|               ||...:....|..
 Frog   308 AAVHVRPD--------------LALIQSMVN---------------CNDKQTKQNESSG------ 337

  Fly   311 NWLDMVHWSNFLAYAPPLPHIQDQFQSPVPGLTFAVNISAGYYSSEHE------AKTDLA--AWS 367
                 .:.|.|||            .:...|.|..:.:|.....:||.      .:..|.  .|.
 Frog   338 -----SYLSRFLA------------NTSFSGQTGQIYVSNNLIHTEHHYRIWSLVRDSLGDPTWV 385

  Fly   368 SVG--------------EMRLLNETISP---ARRFFRIGTAESIPWSYLRREEGTG--------- 406
            :||              :.|:.....:|   ||...|:.|....|:.:.|..:..|
 Frog   386 TVGGWRQGKMEVEEGLWQSRIQQWEPAPGGFARTKLRVVTLVEHPFVFTREVDADGSCPAGQMCL 450

  Fly   407 ---------------ELIRDRSGLPI-----WEGYCIDFIIRLSQKLNFEFEIVAPEVGHMGELN 451
                           ||......:|:     ..|||||.:.:||:.|.|:||:.....|..| ..
 Frog   451 DPRTNNSAVLDVLFEELNSPNGSVPLEYKTCCYGYCIDLLEKLSEDLRFDFELYIVGDGKYG-AR 514

  Fly   452 ELGEWDGVVGDLVRGETDFAIAALKMYSEREEVIDFLPPYYEQTGISIAIRKPVRRTSLFKFMTV 516
            :...|.|:||||:.|....|:.:..:.|.|..||||..|:| .|.:.|.:|.....:.:..||..
 Frog   515 KGDRWTGLVGDLLSGAAHMAVTSFSINSARSTVIDFTSPFY-STSLGILVRMRDTASPIGAFMWP 578

  Fly   517 LRLEVWLSIVAALVGTAIMIWFMDKYSPYS----SRNNRQAYPYACREFTLRESFWFALTSFTPQ 577
            |...:|:.|..||..||:.:.|.:..||:.    .||..:.:.|: ....|..:..|..|.
 Frog   579 LHWSMWVGIFVALHITALFLTFYEWKSPFGMTPHGRNRTKIFSYS-SALNLCYAILFGRTV---- 638

  Fly   578 GGGEAPKAISGRMLVAAYWLFVVLMLATFTANLAAFLTVERMQTPVQSLE--QLARQSR-INYTV 639
             ..:.||..:||:|:..:.:|.:|:|:::||||||.:..::....:..:.  :|...|: ..:..
 Frog   639 -SSKTPKCCTGRVLMNLWAIFCLLVLSSYTANLAAVMVGDKTFEALSGIHDPKLHHPSQGFRFGT 702

  Fly   640 VKDSDTHQYFVNMKFAEDTLYRMWKELALNASKDFKKFRIWDYPIKEQYGHILLAINSSQPVADA 704
            |.:|...|| :...|.|...|             .:||.:   |......|:|   .:..|..:
 Frog   703 VWESSAEQY-IKKSFPEMHNY-------------MRKFSV---PATSDGVHLL---KTDPPTLN- 746

  Fly   705 KEGFANVDAHENADYAFIHDSAEIKYEIT--RNCNLTEVGEVFAEQPYAVAVQQGSHLGDELSYA 767
                           |||.|.|.:.||::  .:|.|..:|:.||.:.|.:.:.|.|.|...:|..
 Frog   747 ---------------AFIMDKALLDYEVSIDSDCKLLTIGKPFAIEGYGIGLPQNSPLTSNISEF 796

  Fly   768 ILELQKDRFFEELKAKYWNQSNLPNCPLSEDQEGITLESL-------GGVFIATLFGLVLAMMTL 825
            |...:...|.:.|..|::..     .|..:....:| |:|       .|:|:....|...:::|.
 Frog   797 ISRYKSSGFMDTLHDKWYKM-----VPCGKRVYAVT-ETLQMGIYHFSGLFVLLCIGFCGSLLTS 855

  Fly   826 GMEVLYY 832
            .||.:.|
 Frog   856 LMERVVY 862

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir8a	NP_727328.1	PBP2_iGluR_putative	383..786	CDD:270435	109/440 (25%)
		Lig_chan	520..818	CDD:278489	71/313 (23%)
grin3b	XP_017952374.2	PBP1_iGluR_NMDA_NR3	29..402	CDD:380600	73/405 (18%)
		PBP2_iGluR_NMDA_Nr3	418..814	CDD:270438	109/439 (25%)
		Lig_chan	582..848	CDD:395014	71/313 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910