Protein Alignment Ir8a and grik4

DIOPT Version :9

• Sequence 1: NP_727328.1
• Gene: Ir8a / 31867
• FlyBaseID: FBgn0052704
• Length: 936
• Species: Drosophila melanogaster
• Sequence 2: XP_031761990.1
• Gene: grik4 / 100490768
• XenbaseID: XB-GENE-1011875
• Length: 962
• Species: Xenopus tropicalis
• Alignment Length: 1057
• Identity: 238/1057 - (22%)
• Similarity: 421/1057 - (39%)
• Gaps: 276/1057 - (26%)

  Fly     5 LLVLLLALRFAGSEVLKITFWIEPVQRAEFDTDIAMVL---------KELDALRLDVKVDDTTLT 60
            :||||..::.|||..|:|...::..........:::.|         :.....||:|.:    ..
 Frog     9 VLVLLWLMKSAGSPSLRIAAILDDPMECSRGERLSITLAKNRINRAPERQGKARLEVDI----FE 69

  Fly    61 LTRSEDGLDMQRFCEILSTVGASAVIDLTYSHWEEGY--NLVRSLGIGYVRL--ERIMRPFLDMF 121
            |.:..:....:..|:||.. |...|:..:||......  |:.....:.::::  |..:|.....|
 Frog    70 LLKDSEYETAETMCQILPK-GVLGVLGPSYSPSSSSIISNICGEKEVPHIKVSTEEFLRFQYQRF 133

  Fly   122 GDFMRQKRANNVA------MVFMNARDAV-------------EAMQQMLVGYPFRTLIMDASQTD 167
            ..........:::      :.|.|:..|.             :.::|.|:.....::.|.....|
 Frog   134 TTLNLHPSNTDISAAVATLLRFFNSTTACLICAKAECLLNLEKLLRQFLISKDCLSVRMLDDTWD 198

  Fly   168 PGQHFLERIRSLRPAPTYIALFARAAAMNGIFEKVQKADL------------------FQRPLEW 214
            | ...|:.||..:.:.  |.:.|.|:..:.|..|..:..:                  |:.||:
 Frog   199 P-TPLLKEIRDDKTST--IIVHANASMSHTILMKAAELGMVTAYYTYIFTNLEFVLQRFESPLD- 259

  Fly   215 HFVFLDTRDRV----FKYRRQA-----ELCTRFTLNPRAICRSMPMPDLYCGSGFTMQRAMLLNV 270
                    |||    |....|:     |.......:....|...|.      :|..:..|:|.:.
 Frog   260 --------DRVNILGFSMFNQSHSYFKEFAHTLQQSWEENCDHSPF------TGPALSAALLFDA 310

  Fly   271 LRSLINAAQ---------VSPGYPLAIYQDCNATASSSEVSDPLEKDDYNWLDMVHWSNFLAYAP 326
            :..:::|.|         |.|           .:..||::          |.......|:|...
 Frog   311 VYGIVSAVQELNRSQEIGVKP-----------LSCGSSQI----------WQHGTSLMNYLRMV- 353

  Fly   327 PLPHIQDQFQSPVPGLTFAVNISAGYYSSEHEAKT---DLAAWSSVGEMRLLNETISPARRFFRI 388
                       .:.|||..|..::....|.::.|.   ....:..:|:..:.| .::..:|:|..
 Frog   354 -----------ELEGLTGHVEFNSKGQRSNYDMKIMQYTKTGFQEIGQWHVTN-GLNMDKRYFSP 406

  Fly   389 GTAESI-----------------PWSYLRREEGTGELIRDRSGLPIWEGYCIDFIIRLSQKLNFE 436
            ..::::                 |:..|:...      ::..|...:||:|:|.:..|:..|.|.
 Frog   407 NASDTLVNKTLIVTTILFFLQENPYLMLKANH------QELEGNDRYEGFCVDMLKELAAILRFN 465

  Fly   437 FEI--VAPEVGHMGELNELGEWDGVVGDLVRGETDFAIAALKMYSEREEVIDFLPPYYEQTGISI 499
            ::|  ||..|..:.|||  |.|.|:||:|:..:.|.|:|.|.:.:|||:||||..|:. ..||||
 Frog   466 YKIRLVADGVYGVPELN--GTWTGMVGELISRKADLAVAGLTITAEREKVIDFSKPFM-TLGISI 527

  Fly   500 AIRKPV-RRTSLFKFMTVLRLEVWLSIVAALVGTAIMIWFMDKYSPYSSRNNRQAYPYAC----- 558
            ..|..: |:...|.|:......|||.::.|.:..:.:::.:.:.:||...:     |:.|
 Frog   528 LYRVHMGRKPGYFSFLDPFSPGVWLFMLLAYLAVSCVLFLVARLTPYEWYS-----PHPCAQGRC 587

  Fly   559 ----REFTLRESFWFALTSFTPQGGGEAPKAISGRMLVAAYWLFVVLMLATFTANLAAFLTVERM 619
                .:::|..|.||.:..|..||...||:|:|.|.:...:|.|.:::::::||||||||||:||
 Frog   588 NLLVNQYSLGNSLWFPVGGFMQQGSTIAPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRM 652

  Fly   620 QTPVQSLEQLARQSRINYTVVKDSDTHQYFVNMKFAEDTLYRMWKELALNASKDFKKFRIWDYPI 684
            ..|::|::.||.|:.|.|..:....:..:|.|.::  .|..|||
 Frog   653 DVPIESVDDLADQTTIEYGTIHGGSSMTFFQNSRY--QTYQRMW--------------------- 694

  Fly   685 KEQYGHILLAINSSQP---VADAKEGFANVDAHENADYAFIHDSAEIKYEITRNCNLTEVGEVFA 746
              .|.|      |.||   |...:||.|.|   .|::|||:.:|...:|...||||||:||.:..
 Frog   695 --NYMH------SKQPSVFVKSTEEGIARV---LNSNYAFLLESTMNEYYRQRNCNLTQVGGLLD 748

  Fly   747 EQPYAVAVQQGSHLGDELSYAILELQKDRFFEELKAKYWNQSNLPNCPLSEDQ--EGITLESLGG 809
            .:.|.:.:..||...||...|||:||::...|:||.|:|:..   .||..||.  :|:.:|::||
 Frog   749 TKGYGIGMPVGSAFRDEFDLAILQLQENNCLEDLKRKWWDGG---KCPKEEDHRAKGLGMENIGG 810

  Fly   810 VFIATLFGLVLAMMTLGMEVLYYKK----------KQNALEITQV-------------------R 845
            :|:..:.||::|::...:|.|:..:          ::.|.|::.:                   |
 Frog   811 IFVVLICGLIVAILIAMLEFLWTVRNAEDSEVSVCQEMASELSSIILCKDSFLPRRRRGGVIRGR 875

  Fly   846 PVNDSSGSGGNSS----------TAPPTATSTTKQ--------AWHIPVLEAEEKPAKVSPPPSF 892
            |:......|.|:|          :.|...|....|        ..||          :|.|
 Frog   876 PITQDDRRGRNTSILSNGKLCGGSGPDPLTQRLAQEAALVARGCTHI----------RVCP---- 926

  Fly   893 ETATFRGKKLPARITLG 909
            |...|:|  |.||.::|
 Frog   927 ECRRFQG--LRARTSVG 941

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir8a	NP_727328.1	PBP2_iGluR_putative	383..786	CDD:270435	130/434 (30%)
		Lig_chan	520..818	CDD:278489	95/311 (31%)
grik4	XP_031761990.1	Periplasmic_Binding_Protein_type1	23..400	CDD:415822	65/433 (15%)
		PBP2_iGluR_kainate_KA1	414..788	CDD:270442	128/421 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010