Protein Alignment Ir8a and gria1

DIOPT Version :9

• Sequence 1: NP_727328.1
• Gene: Ir8a / 31867
• FlyBaseID: FBgn0052704
• Length: 936
• Species: Drosophila melanogaster
• Sequence 2: XP_004912781.1
• Gene: gria1 / 100127569
• XenbaseID: XB-GENE-995621
• Length: 903
• Species: Xenopus tropicalis
• Alignment Length: 914
• Identity: 216/914 - (23%)
• Similarity: 376/914 - (41%)
• Gaps: 225/914 - (24%)

  Fly     5 LLVLLLALRFAGSEVLKITFWIEPVQRAEFDTDIAMVLKELD-ALRLDVKVDDTTLTLTRSEDG- 67
            :|.|...|:.|...|::...|.:.|...:.|..::::.|.|| |...:.:|....: ||.:|:|
 Frog   122 VLQLRPELQDALISVIEYYKWKKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNI-LTTTEEGY 185

  Fly    68 ------LDMQRFCEI--------LSTVGASAVIDLTYSHWEE---GYN-LVRSLGIGYVRLERIM 114
                  ||..:..:|        |:.:....|:.|     |:   ||: ::.:||
 Frog   186 RLLFQDLDKSKDRQIVIDCESERLNAILTQVVVKL-----EKNIIGYHYILANLG---------- 235

  Fly   115 RPFLDMFGDFMRQKRANNVAMVFMNARDA-VEAMQQMLVGYPFRTLIMDASQTDPGQHFLERIRS 178
              |:|:.....::..||......:|..|. |..:.|....|..|        ..|      |:..
 Frog   236 --FMDIDMQKFKEAGANVTGFQLVNYTDTMVSRIMQQWKNYDGR--------EQP------RVDW 284

  Fly   179 LRPAPTYIALFARAAAMNGIFEKVQKADLFQRPLEWHFVFLDTRDRVFKYRRQAELCTRFTLNPR 243
            .:|..|....:.....|...|:.::|    ||        :|     ...|..|..|
 Frog   285 KKPKYTSALTYDGVRVMAEAFQSLRK----QR--------ID-----ISRRGNAGDC-------- 324

  Fly   244 AICRSMPMPDLYCGSGFTMQRAMLLNVLRSLINAAQVS-----PGYPLAIYQDCNATASSSEVSD 303
                 :..|.:..|.|..:|||:....|..|....|.:     ..|.|.:
 Frog   325 -----LANPAVPWGQGIDIQRALQQVRLEGLSGNVQFNEKGRRTNYTLHV--------------- 369

  Fly   304 PLEKDDYNWLDMVHWSNFLAYAPPLPHIQDQFQSPVPGLTFAVNISAGYYSSEHEAKTDLAAWSS 368
             ||........:.||:            :|....|:     |.:..||
 Frog   370 -LELKHEGIRHIAHWN------------EDDKLIPL-----ATDAQAG----------------- 399

  Fly   369 VGEMRLLNETISPARRFFRIGTAESIPWSYLRRE----EGTGELIRDRSGLPIWEGYCIDFIIRL 429
                   |:||....|.:.:.|....|:..|::.    ||     .||     :||||::....:
 Frog   400 -------NDTIGVQNRTYIVTTILEAPYVMLKKNADQLEG-----NDR-----FEGYCVELAAEI 447

  Fly   430 SQKLNFEFEIVAPEVGHMGEL-NELGEWDGVVGDLVRGETDFAIAALKMYSEREEVIDFLPPYYE 493
            ::.:.|::::...:.|..|.. :::..|:|:||:||.|..|.|:|.|.:...|||||||..|:.
 Frog   448 AKHVGFKYKLEIVKDGKYGARDSDMKAWNGMVGELVYGRADLAVAPLTITLVREEVIDFSKPFM- 511

  Fly   494 QTGISIAIRKPVR-RTSLFKFMTVLRLEVWLSIVAALVGTAIMIWFMDKYSPYSSRN------NR 551
            ..||||.|:||.: :..:|.|:..|..|:|:.||.|.:|.:::::.:.::|||...|      ..
 Frog   512 SLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHNEEFEEGKE 576

  Fly   552 QAYPYACREFTLRESFWFALTSFTPQGGGEAPKAISGRMLVAAYWLFVVLMLATFTANLAAFLTV 616
            |.......||.:..|.||:|.:|..||...:|:::|||::...:|.|.:::::::||||||||||
 Frog   577 QPTTDQSNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTV 641

  Fly   617 ERMQTPVQSLEQLARQSRINYTVVKDSDTHQYFVNMKFAEDTLYRMWKELALNASKDFKKFRIWD 681
            |||.:|::|.:.||:|:.|.|..:....|.::|...|.|.                 |:|  :|.
 Frog   642 ERMVSPIESADDLAKQTEIAYGTLDSGSTKEFFKRSKIAV-----------------FEK--MWT 687

  Fly   682 YPIKEQYGHILLAINSSQP---VADAKEGFANVDAHENADYAFIHDSAEIKY-EITRNCNLTEVG 742
            |            :.|::|   |...:||...| ......||::.:|...:| |..:.|:..:||
 Frog   688 Y------------MRSAEPSVFVKTTEEGMNRV-RKSKGKYAYLLESTMNEYIEQRKPCDTMKVG 739

  Fly   743 EVFAEQPYAVAVQQGSHLGDELSYAILELQKDRFFEELKAKYW---NQSNLPNCPLSEDQEGITL 804
            .....:.|.:|..:||.|...::.|:|:|.:....::||:|:|   .:....:....:....::|
 Frog   740 GNLDSKGYGIATPKGSPLRGAVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKDSGSKDKTSALSL 804

  Fly   805 ESLGGVFIATLFGLVLAMMTLGMEVLYYKKKQN----------ALEITQV-------RPVNDSSG 852
            .::.|||...:.||.|||:...:|..|..:.::          ...:|:.       || :.:.|
 Frog   805 SNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKKMKGFCLIPQTTVTETVRMATLPRP-STAGG 868

  Fly   853 SGGN 856
            ||.|
 Frog   869 SGEN 872

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir8a	NP_727328.1	PBP2_iGluR_putative	383..786	CDD:270435	124/421 (29%)
		Lig_chan	520..818	CDD:278489	84/310 (27%)
gria1	XP_004912781.1	PBP1_iGluR_AMPA_GluR1	26..393	CDD:380613	68/365 (19%)
		PBP2_iGluR_AMPA_GluR1	407..788	CDD:270447	124/423 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000