Protein Alignment Ir8a and grid1

DIOPT Version :10

• Sequence 1: NP_727328.1
• Gene: Ir8a / 31867
• FlyBaseID: FBgn0052704
• Length: 936
• Species: Drosophila melanogaster
• Sequence 2: NP_001096470.1
• Gene: grid1 / 100125089
• XenbaseID: XB-GENE-990290
• Length: 1009
• Species: Xenopus tropicalis
• Alignment Length: 1058
• Identity: 232/1058 - (21%)
• Similarity: 377/1058 - (35%)
• Gaps: 355/1058 - (33%)

  Fly     5 LLVLLLALRFAGSEVLKITFWIEPVQRAEFDTDIAMV---LKELDALRLDV---KVDDT------ 57
            :|.|:..||           |.:.:...:.|.||..:   |.:...|.|||   |||..
 Frog   153 MLKLVTELR-----------WQKFIVFYDSDYDIRGLQGFLDQASRLGLDVSLQKVDRNISRVFA 206

  Fly    58 -------TLTLTRSEDGLDMQRFCEILSTVGASAVIDLTY--------SHW---------EEGYN 98
                   |..|.|..|.|  :|...:||..||.:.|....        |||         .|...
 Frog   207 TLFTSMKTEELNRYRDTL--RRAILLLSPRGAQSFISEAVETNLASKDSHWVYVNEEINDAEIVE 269

  Fly    99 LVRSLGIGYVRLERIMRPFLDMFGDFMRQKRANNVAMVFMNARDAVEAMQQMLVGYPFRTLIMDA 163
            ||.| .:|.:.:.|.:.|.|          :.||:..|..|.|.|                   :
 Frog   270 LVHS-ALGRITVIRQIFPSL----------KDNNIRCVRNNHRIA-------------------S 304

  Fly   164 SQTDPGQHFLERIRSLRPAPTYIALFARAAAMNGIFEKV-QKADLFQRPLEWHFVFLDTRDRVFK 227
            ...||.:.:|:   .|:.:..|            :::.| ..|:.|.|.||         ||  |
 Frog   305 LPCDPQEGYLQ---MLQVSNLY------------LYDSVLMLANAFHRKLE---------DR--K 343

  Fly   228 YRRQAEL-CTRFTLNPRAICRSMPMPDLYCGSGFTMQRAMLLNVLRSLINAAQVSPGYPLAIYQD 291
            :...|.| |.|.:..|                 :...|:||..:.:..|...       ..|.:.
 Frog   344 WHSMASLNCMRKSTKP-----------------WNGGRSMLDTIKKGRITGL-------TGIMEF 384

  Fly   292 CNATASSSEVSDPLEKDDYNWLDMVHWSNFLAYAPPLPHIQDQFQSPVPGLTFAVNISAGYYSSE 356
            ..|.|:                               ||:|.:........||..::..
 Frog   385 KEAGAN-------------------------------PHVQFEILGTSYSETFGKDVRR------ 412

  Fly   357 HEAKTDLAAWSSVGEMRLLNETISPARRFFRIGTAESIPWSYLRREEGTGELIRDRSGLPI---- 417
                  ||.|.|   |:..|            |:.:..|            |..|..||.:
 Frog   413 ------LATWDS---MKGFN------------GSLQEKP------------LNNDLQGLTLKVVT 444

  Fly   418 -------------------WEGYCIDFIIRLSQKLNFEFEIVAPEVGHMGELNELGEWDGVVGDL 463
                               ::|:.|:.:..||.:|.|::||.....|..|.....|.|:|::|:|
 Frog   445 VLEEPFVMVAENILGQPKRYKGFSIEILDELSNRLGFKYEIYQAPDGKYGHQLSNGSWNGMIGEL 509

  Fly   464 VRGETDFAIAALKMYSEREEVIDFLPPYYEQTGISIAIRKPVRRTSLFKFMTVLRLEVWLSIVAA 528
            :....|.||:|:.:..|||.|:||...|.:.: :.|.|:||..|.::|.........||..|.|.
 Frog   510 INKRADIAISAITITPERENVVDFTKRYLDYS-VGILIKKPEERINIFSLFAPFDFAVWACIAAV 573

  Fly   529 LVGTAIMIWFMDKYSPYSSRNNRQAYPYACREFTLRESFWFALTSFTPQGGGEAPKAISGRMLVA 593
            :....::|:.:::.....::|:.|.  ......||..:.|....:|..|||..|..:::.|:::.
 Frog   574 IPVVGVLIFVLNRIQAVRAQNSSQT--SQSTSSTLHSAIWIVYGAFVQQGGESAANSVAMRIVMG 636

  Fly   594 AYWLFVVLMLATFTANLAAFLTVERMQTPVQSLEQLARQSRINYTVVKDSDTHQYF----VNMKF 654
            ::|||.:::.:::||||||||||.||..|:::.:.||:|..:.|..||||..::||    .|...
 Frog   637 SWWLFTLIVCSSYTANLAAFLTVSRMDNPIRTFQDLAKQVDLPYGTVKDSSVYEYFKSKGTNTLV 701

  Fly   655 AEDTLYRMWKELALNASKDFKKFRIWDYPIKEQYGHILLAINS-SQPVADAKEGFANVDAHENAD 718
            .:.|...:|:.:..|...|                   ..::| |:.:..||.|          :
 Frog   702 QDRTFAELWRTIGKNNGSD-------------------NCVSSPSEGIRKAKRG----------N 737

  Fly   719 YAFIHDSAEIKYEITRN--CNLTEVGEVFAEQPYAVAVQQGSHLGDELSYAILELQKDRFFEELK 781
            |||:.|...::|....:  |::...|...:.:.|.:|:|.||...|..|..|||.|.....:.||
 Frog   738 YAFLWDVTVVEYAALTDDECSVAVTGNTISSKGYGIALQHGSPYRDIFSQRILEFQDSGRLDVLK 802

  Fly   782 AKYWNQSNLPNCPLS------EDQEGITLESLGGVFIATLFGLVLAMMTLGMEVLYYKK------ 834
            .|:|.::.  .|.|:      .|.:.:.|.|..|||.....||:||.:...:|:.:...
 Frog   803 EKWWPRTG--RCDLNSHNNAQNDGKALKLHSFAGVFCILAIGLLLACLVAALELWWNSNRCRQDS 865

  Fly   835 --------------------------KQ--------NALEI-----TQVRPVND----------- 849
                                      ||        :||||     ..:.|:.:
 Frog   866 PKEDKEVNLEQVHRRLNSLIDEDMAHKQISTASIEISALEIGGMPSQTLEPLREYQSTQLSVTTF 930

  Fly   850 ----SSGSGGN------SSTAP-PTATSTTKQAWHIPVLEAE----------EKPAKVSPPPSFE 893
                :..|||.      ||..| |.::|.|     :|.::.:          :.|.|...|.||:
 Frog   931 LPEQTGHSGGRTLTSIPSSNLPLPLSSSAT-----MPSMQCKHRSPNGGLFRQSPVKTPMPLSFQ 990

  Fly   894 TATFRGKKLPARITLGDG 911
              :..|..:|..|....|
 Frog   991 --SMPGGPIPEAIETSHG 1006

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir8a	NP_727328.1	PBP2_iGluR_putative	383..786	CDD:270435	111/432 (26%)
grid1	NP_001096470.1	PBP1_iGluR_delta_1	25..426	CDD:380615	82/423 (19%)
		PBP2_iGluR_delta_1	437..807	CDD:270448	107/401 (27%)