DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31296 and CRISPLD1

DIOPT Version :9

Sequence 1:	NP_001262608.1	Gene:	CG31296 / 318668	FlyBaseID:	FBgn0051296	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	NP_113649.1	Gene:	CRISPLD1 / 83690	HGNCID:	18206	Length:	500	Species:	Homo sapiens

Alignment Length:	245	Identity:	52/245 - (21%)
Similarity:	89/245 - (36%)	Gaps:	97/245 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 NARTLSMSTYRNLLLIAFNEFRNYTASGKQKYLKAAAARMSRL-SYSMELEDLARLAVITCSTHK 114
            :.||.|..:.||.::                    :|.:||:: |..:.|.|..:  ..||:.::
Human   270 HVRTRSDDSSRNEVI--------------------SAQQMSQIVSCEVRLRDQCK--GTTCNRYE 312

  Fly   115 F---CLNSQEFYYVGTNIGSTHYLGNLNDYEDLELMLRIIQHWTRY------ADYVNIKMGVYMP 170
            .   ||:|:     ...|||.||          |:...|.:....|      ..:|:|
Human   313 CPAGCLDSK-----AKVIGSVHY----------EMQSSICRAAIHYGIIDNDGGWVDI------- 355

  Fly   171 TTLGKSGIAKALLLMADRN--THVG--CSAMRFTVHSVHNFVFLCAFSTDLFVER--PIYRMSMR 229
            |..|:    |...:.::||  ..:|  .||..|||..    |.:.|.:.:..||:  |.:    :
Human   356 TRQGR----KHYFIKSNRNGIQTIGKYQSANSFTVSK----VTVQAVTCETTVEQLCPFH----K 408

  Fly   230 PGAACKRL---------DPTYSALCAVGENYENNKPMLNARVFQLPLDLS 270
            |.:.|.|:         :|.|:.             ::..||:.   |||
Human   409 PASHCPRVYCPRNCMQANPHYAR-------------VIGTRVYS---DLS 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31296	NP_001262608.1	SCP_euk	61..214	CDD:240180	36/166 (22%)
CRISPLD1	NP_113649.1	SCP_euk	63..207	CDD:240180
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	254..281		3/10 (30%)
		LCCL	291..375	CDD:128866	23/111 (21%)
		LCCL	392..483	CDD:128866	14/71 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920