DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31296 and GLIPR1L2

DIOPT Version :9

Sequence 1:	NP_001262608.1	Gene:	CG31296 / 318668	FlyBaseID:	FBgn0051296	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	NP_001257325.1	Gene:	GLIPR1L2 / 144321	HGNCID:	28592	Length:	344	Species:	Homo sapiens

Alignment Length:	215	Identity:	47/215 - (21%)
Similarity:	77/215 - (35%)	Gaps:	50/215 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 NARTLS-------MSTYRNLLLIAFNEFRNYTASGKQKYLKAAAARMSRLSYSMELEDLARLAVI 108
            |||.|.       ::.|.||    .||.|....        ...:.:..:::.:.|...||....
Human    41 NARFLPDEEDVDFINEYVNL----HNELRGDVI--------PRGSNLRFMTWDVALSRTARAWGK 93

  Fly   109 TC-STHKFCLNS-----QEFYYVGTNIGSTHYLGNLNDYEDLELMLRIIQHWTRYADYVNIKMGV 167
            .| .||...|..     .:||.:|.|:    ::|..|::    .....|:.|.......|.:.|
Human    94 KCLFTHNIYLQDVQMVHPKFYGIGENM----WVGPENEF----TASIAIRSWHAEKKMYNFENG- 149

  Fly   168 YMPTTLGKSG-IAKALLLMADRNTHVGCSAMRFTV--HSVHNFVFLCAFSTDLFVERPIYRMSMR 229
                  ..|| .:..:.|:.|.:..|||:....:.  |.:|..:|:|.::....:.|..|    .
Human   150 ------SCSGDCSNYIQLVWDHSYKVGCAVTPCSKIGHIIHAAIFICNYAPGGTLTRRPY----E 204

  Fly   230 PG---AACKRLDPTYSALCA 246
            ||   ..|.|.|.....||:
Human   205 PGIFCTRCGRRDKCTDFLCS 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31296	NP_001262608.1	SCP_euk	61..214	CDD:240180	33/161 (20%)
GLIPR1L2	NP_001257325.1	SCP_GLIPR-1_like	52..195	CDD:240185	34/169 (20%)
GLIPR1L2	NP_001257325.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	292..344
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820