DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31288 and CG6834

DIOPT Version :9

Sequence 1:	NP_733094.1	Gene:	CG31288 / 318664	FlyBaseID:	FBgn0051288	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	NP_650104.2	Gene:	CG6834 / 41409	FlyBaseID:	FBgn0037935	Length:	895	Species:	Drosophila melanogaster

Alignment Length:	424	Identity:	144/424 - (33%)
Similarity:	234/424 - (55%)	Gaps:	29/424 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 NPNEHLIIPDWINEKYFESVLAKDEPDHVKVLKFTVVAAIPPGENFTSTMLRVYIKLEMKDGSVK 73
            ||...::  ||:|...|..|::..||:..|::..:..:|..||:||.|.:|::.|:.::||.:.|
  Fly   490 NPKNQIL--DWLNVSDFAEVISSAEPEFDKIVGGSWSSATKPGDNFASKLLKIDIETQLKDHTSK 552

  Fly    74 TKTYIFKTM---LPEERGGSDINEFGLFPKEAMMYKTYLPAFEALYKDVGWDIQLAPKCLHTEER 135
            |.:||.|..   .|:  ..:|:|   :||||..||:.|:||||.||||.|..:..........:.
  Fly   553 TFSYILKVQPKSTPD--NFTDVN---MFPKEMEMYQKYVPAFEQLYKDAGLTVTFTANSFVLNKA 612

  Fly   136 EGDIHFIFEDLCVKRFKNMDRTKGLDMEHMTKCLQKLAEYHAASAVYEELHGPYPSEFSEG-FVK 199
            ..:.:.:.|:|..|.||..||.|||:|||....|:|||::||||..|:||:|.||..:::| :::
  Fly   613 VKEEYLLMENLQTKGFKMADRMKGLNMEHTKSSLKKLAQWHAASIKYKELNGAYPPLYNDGIYIE 677

  Fly   200 KDVKKFHVDGFQLKEKAYKKAMLSWGLKDADKYIKAFPTVKQYWA------QCLSTLELNPDEFH 258
            :....|| :.|...::||.:...::  :.||:|:.     |..|.      |.|...::|...|:
  Fly   678 QTRDVFH-NMFASAKEAYIRIFGTF--EGADEYLP-----KLEWIIDNHVDQVLEDAKINEQAFN 734

  Fly   259 VLNHGDFWSSNLMSSYLPDGTLEKLILIDFQIVMWGSPAMDLLFFLTLSPTNDLRIKEFDHFVRI 323
            ||||||.|.:|:|..|..:|.|::..|:|.|...:|:||.||.:||..|...|:::.|||:.:|.
  Fly   735 VLNHGDAWINNIMFQYDAEGRLKETYLLDHQNAKYGNPAQDLYYFLISSAELDIKVDEFDNLIRF 799

  Fly   324 YWERLVECLKVLKLKKPLPKLRDLQNSMNNKNHSFYAFFSILNHLPIILFPTDKDSNIHNLSANT 388
            |.|.|||..|:||....:|.|.:|...:  ..|..:|..::::.|.:.|  ||:..|.......|
  Fly   800 YHENLVEHTKLLKYNGFVPSLSELHAIL--IEHPAFAVGTVISTLTVCL--TDEGFNPELFFVET 860

  Fly   389 EEGENYRLRLLSNPAFGNVMKDLYPFLYNRGILN 422
            .|.|.:|.:||.|..:...::.:.|:|..||:|:
  Fly   861 PESEAFRTKLLGNERYKAHVEKIMPWLNRRGLLD 894

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31288	NP_733094.1	EcKinase	50..331	CDD:281023	107/290 (37%)
CG6834	NP_650104.2	EcKinase	95..387	CDD:281023
CG6834	NP_650104.2	EcKinase	529..813	CDD:281023	110/296 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442546
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S12411
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D27900at6960
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.800